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CAZyme Information: MGYG000002418_00066
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Parabacteroides chinchillae | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae; Parabacteroides; Parabacteroides chinchillae | |||||||||||
| CAZyme ID | MGYG000002418_00066 | |||||||||||
| CAZy Family | GH20 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 69133; End: 71310 Strand: - | |||||||||||
Full Sequence Download help
| MQLPKQSFKH VALCMVASAF LMGACTPKQT MRVNLIPKPA EMVVGTGYFQ ADTNLLMGEG | 60 |
| QSGTIRYILH ENFDGGNLEA YRLKVTSKGI EAEAATGAGL FYAKQTLRQL VTPEGIPYVD | 120 |
| IYDTPRFPYR GLHLDVSRHF FPKEEVFKLL DAMAYYKLNT LHFHLTDAGG WRFQSDKYPK | 180 |
| LTAEGAFRTE SDWQKWWDGK DRQYLPEGTP GAYGGYYTKE DIKQMVAYAT ERHINIIPEI | 240 |
| EFPGHSDEVL FAYPELSCSG KPYQNGDFCI GNPKSFAFME DILTEVTDLF SSKYIHIGGD | 300 |
| EAGKGAWKKC PKCQALMAKK GMKSVDELQS YMIHRAEEFL ISKGRKLIGW DEILEGGLAP | 360 |
| EATVMSWRGE NGGIKAARMG HDVIMTPGGY MYFDFYQADP KTQPYAIGGY TPVKHVYSYN | 420 |
| PVPVDSLTAE ESKHIIGVQA NTWTEYIQTT DHLEYMMFPR ALALAEIAWT PQDLRSWEDF | 480 |
| KPRMNANIPV LQKMGINTFT LSDEIEAVMK VDAVKKQIEV VLDAEKYPAE IRYTTDGSVP | 540 |
| TASSTLYKGA IVVKDSAYIK AAIFRDGKLQ GTPTEKKVDY HRGINKPIHY NSKLYSGYMA | 600 |
| GGMNALLDGY RGGLTYLDGR WQGYLNDLDC VVDMEEATDI HKVSIRFMQL IGPGVFQPGE | 660 |
| VELLTSEDGE NFISRGVVPT TISNTDKDLS FQEYTFSGDW KARYIRLKAT EVNNGFIFAD | 720 |
| EIVIW | 725 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH20 | 123 | 472 | 3e-121 | 0.973293768545994 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd06563 | GH20_chitobiase-like | 0.0 | 127 | 484 | 1 | 357 | The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself. |
| pfam00728 | Glyco_hydro_20 | 3.09e-166 | 127 | 471 | 1 | 345 | Glycosyl hydrolase family 20, catalytic domain. This domain has a TIM barrel fold. |
| COG3525 | Chb | 1.12e-130 | 15 | 571 | 116 | 709 | N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]. |
| cd06568 | GH20_SpHex_like | 3.88e-98 | 127 | 484 | 1 | 329 | A subgroup of the Glycosyl hydrolase family 20 (GH20) catalytic domain found in proteins similar to the N-acetylhexosaminidase from Streptomyces plicatus (SpHex). SpHex catalyzes the hydrolysis of N-acetyl-beta-hexosaminides. An Asp residue within the active site plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself. Proteins belonging to this subgroup lack the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. |
| cd06569 | GH20_Sm-chitobiase-like | 1.48e-88 | 123 | 478 | 1 | 421 | The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QCY55921.1 | 0.0 | 1 | 725 | 1 | 725 |
| QUT53805.1 | 0.0 | 1 | 725 | 1 | 725 |
| QIX66554.1 | 0.0 | 1 | 725 | 1 | 725 |
| QUR46985.1 | 0.0 | 1 | 725 | 1 | 725 |
| QJE28072.1 | 0.0 | 1 | 725 | 1 | 725 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6Q63_A | 3.40e-164 | 60 | 724 | 87 | 773 | BT0459[Bacteroides thetaiotaomicron],6Q63_B BT0459 [Bacteroides thetaiotaomicron],6Q63_C BT0459 [Bacteroides thetaiotaomicron] |
| 7CBN_A | 5.50e-104 | 79 | 497 | 78 | 509 | Crystalstructure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila [Akkermansia muciniphila ATCC BAA-835],7CBO_A Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila in complex with GlcNAc [Akkermansia muciniphila ATCC BAA-835] |
| 7DUP_A | 7.80e-92 | 79 | 497 | 79 | 519 | ChainA, Beta-N-acetylhexosaminidase [Bacteroides thetaiotaomicron],7DVA_A Chain A, Beta-N-acetylhexosaminidase [Bacteroides thetaiotaomicron],7DVA_B Chain B, Beta-N-acetylhexosaminidase [Bacteroides thetaiotaomicron] |
| 7DVB_A | 4.21e-91 | 79 | 497 | 79 | 519 | ChainA, Beta-N-acetylhexosaminidase [Bacteroides thetaiotaomicron],7DVB_B Chain B, Beta-N-acetylhexosaminidase [Bacteroides thetaiotaomicron],7DVB_C Chain C, Beta-N-acetylhexosaminidase [Bacteroides thetaiotaomicron],7DVB_D Chain D, Beta-N-acetylhexosaminidase [Bacteroides thetaiotaomicron] |
| 3RCN_A | 2.89e-90 | 65 | 502 | 67 | 517 | CrystalStructure of Beta-N-Acetylhexosaminidase from Arthrobacter aurescens [Paenarthrobacter aurescens TC1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P49008 | 1.49e-122 | 57 | 547 | 89 | 581 | Beta-hexosaminidase OS=Porphyromonas gingivalis (strain ATCC BAA-308 / W83) OX=242619 GN=nahA PE=3 SV=2 |
| B2UQG6 | 4.13e-103 | 79 | 497 | 97 | 528 | Beta-hexosaminidase Amuc_0868 OS=Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) OX=349741 GN=Amuc_0868 PE=1 SV=1 |
| P96155 | 1.14e-82 | 80 | 465 | 209 | 601 | Beta-hexosaminidase OS=Vibrio furnissii OX=29494 GN=exoI PE=1 SV=1 |
| B2UP57 | 7.93e-74 | 79 | 484 | 58 | 462 | Beta-hexosaminidase Amuc_2018 OS=Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) OX=349741 GN=Amuc_2018 PE=1 SV=1 |
| Q04786 | 3.08e-59 | 80 | 479 | 266 | 724 | Beta-hexosaminidase OS=Vibrio vulnificus OX=672 GN=hex PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000000 | 0.000007 | 1.000064 | 0.000000 | 0.000000 | 0.000000 |