CAZyme Information: MGYG000003143_00771

Basic Information

• Species: Clostridium_J sp900548455
• Lineage: Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium_J; Clostridium_J sp900548455
• CAZyme ID: MGYG000003143_00771
• CAZy Family: GH29
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
341	MGYG000003143_4|CGC1	39412.51	5.8076

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003143	3911084	MAG	United States	North America

• Gene Location: Start: 27951; End: 28976 Strand: -

Full Sequence      

MNENIEWFKKAKFGMMIHWGLYSLLAGEYKGEKSSVYAEWIQSKFQIPNREYEKLASAFN
PIYFNADEIVTLAKKCGMTYLVVTSKHHDGFAMYHSKVDKYNVYDATPFHRDVMAELSNA
CKKHGLKFGIYYSQDLDWHEPNGGGYLSNHIETAGTTWDNSWDFKGTKDFNICFENKIIP
QIKEIMTNYGEIFTAWFDMPMTLTKKQSEKIYNTVKELQPNCLINSRLGNGKYDYVSLGD
NEIPEKMDILNDTDIDYNSVDGIKPSPYGLYETAATMNNTWGFSYHDQNWKSSDEIYKYK
NHLNSIGINYLLNVGLDGLGRIPMESIKILNSIVERDNEVK

Enzyme Prediction     

No EC number prediction in MGYG000003143_00771.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH29	2	333	8.6e-85	0.8497109826589595

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam01120	Alpha_L_fucos	2.18e-75	6	333	20	324	Alpha-L-fucosidase.
smart00812	Alpha_L_fucos	9.56e-69	6	333	21	326	Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis.
COG3669	AfuC	3.17e-24	18	330	1	305	Alpha-L-fucosidase [Carbohydrate transport and metabolism].
pfam14871	GHL6	1.26e-04	65	131	1	65	Hypothetical glycosyl hydrolase 6. GHL6 is a family of hypothetical glycoside hydrolases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ALB28421.1	5.41e-202	1	338	1	339
AYE37750.1	2.76e-200	1	338	1	339
AKU60913.1	5.65e-196	1	324	1	326
ARE44411.1	5.65e-196	1	324	1	326
QDR74560.1	5.65e-196	1	324	1	326

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6O18_A	1.76e-196	1	324	1	326	ChainA, AlfC [Lacticaseibacillus casei],6O18_B Chain B, AlfC [Lacticaseibacillus casei],6O18_C Chain C, AlfC [Lacticaseibacillus casei],6O18_D Chain D, AlfC [Lacticaseibacillus casei],6O1A_A Chain A, AlfC [Lacticaseibacillus casei],6O1A_B Chain B, AlfC [Lacticaseibacillus casei],6O1A_C Chain C, AlfC [Lacticaseibacillus casei],6O1A_D Chain D, AlfC [Lacticaseibacillus casei]
6O1I_A	1.44e-195	1	324	1	326	ChainA, AlfC [Lacticaseibacillus casei],6O1I_B Chain B, AlfC [Lacticaseibacillus casei],6O1I_C Chain C, AlfC [Lacticaseibacillus casei],6O1I_D Chain D, AlfC [Lacticaseibacillus casei]
6O1J_A	2.90e-195	1	324	1	326	ChainA, AlfC [Lacticaseibacillus casei],6O1J_B Chain B, AlfC [Lacticaseibacillus casei],6O1J_C Chain C, AlfC [Lacticaseibacillus casei],6O1J_D Chain D, AlfC [Lacticaseibacillus casei],6O1J_E Chain E, AlfC [Lacticaseibacillus casei],6O1J_F Chain F, AlfC [Lacticaseibacillus casei],6O1J_G Chain G, AlfC [Lacticaseibacillus casei],6O1J_H Chain H, AlfC [Lacticaseibacillus casei]
6O1C_A	2.90e-195	1	324	1	326	ChainA, AlfC [Lacticaseibacillus casei],6O1C_B Chain B, AlfC [Lacticaseibacillus casei],6O1C_C Chain C, AlfC [Lacticaseibacillus casei],6O1C_D Chain D, AlfC [Lacticaseibacillus casei],6O1C_E Chain E, AlfC [Lacticaseibacillus casei],6O1C_F Chain F, AlfC [Lacticaseibacillus casei],6O1C_G Chain G, AlfC [Lacticaseibacillus casei],6O1C_H Chain H, AlfC [Lacticaseibacillus casei],6OHE_A Chain A, AlfC [Lacticaseibacillus casei],6OHE_B Chain B, AlfC [Lacticaseibacillus casei],6OHE_C Chain C, AlfC [Lacticaseibacillus casei],6OHE_D Chain D, AlfC [Lacticaseibacillus casei]
7DB5_A	2.34e-64	3	333	32	348	ChainA, Alpha-L-fucosidase [Vibrio sp. EJY3]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P17164	1.09e-20	6	141	47	187	Tissue alpha-L-fucosidase OS=Rattus norvegicus OX=10116 GN=Fuca1 PE=1 SV=1
Q2KIM0	1.28e-19	7	141	55	194	Tissue alpha-L-fucosidase OS=Bos taurus OX=9913 GN=FUCA1 PE=2 SV=1
Q99LJ1	5.39e-19	6	156	37	197	Tissue alpha-L-fucosidase OS=Mus musculus OX=10090 GN=Fuca1 PE=1 SV=1
P04066	1.05e-18	7	156	52	211	Tissue alpha-L-fucosidase OS=Homo sapiens OX=9606 GN=FUCA1 PE=1 SV=4
P49713	1.12e-18	6	141	32	173	Putative alpha-L-fucosidase OS=Caenorhabditis elegans OX=6239 GN=W03G11.3 PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999874	0.000142	0.000002	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003143_00771.