CAZyme Information: MGYG000001015_00114

Basic Information

• Species: Gemmiger sp900556255
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Gemmiger; Gemmiger sp900556255
• CAZyme ID: MGYG000001015_00114
• CAZy Family: GH33
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
386		42954.32	4.8313

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001015	1427844	MAG	United Kingdom	Europe

• Gene Location: Start: 3538; End: 4698 Strand: +

Full Sequence      

MTYAKLPGLTWDGTVYENEEMGTLEALLPTGGYPTAHAPAMVELPDGDLLCCWFAGTYEG
CADIHIICSCLPHDGTAWLPPVDISKDPTRSEQNPSLFYGPDNAVWAMYTAQLDRQAGKD
NMQYTAVVRCQKSTDGGKTWGDYTTVFPEEGTFCRQPIQILSNGRWIFANWLCTDSVDGL
SGDPTAFRISDDEGETWKMVMMPKSNGHVHANVVELEPGHLVAFMRNREAWRIHRSESFD
YGDTWTEPAPTPLPNNNSSISALKLQSGRIAIAYNPTCTPDPQPGKAAWPGLRCPVAVAL
SEDGGLTFPILRWMERGEGYMGDENKTNNKQYEYPYLMQSRDGMLHLAYAARTRQGIKYV
RFSEQDVLGVKRETVGLYNPTAAQAR

Enzyme Prediction     

No EC number prediction in MGYG000001015_00114.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH33	30	363	1.1e-34	0.9473684210526315

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd15482	Sialidase_non-viral	5.95e-63	30	363	8	339	Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
pfam13088	BNR_2	2.82e-58	47	347	1	280	BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
COG4692	COG4692	4.80e-36	22	362	20	371	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AXB29891.1	6.94e-283	1	386	1	386
CBL01983.1	1.40e-282	1	386	1	386
CBK76990.1	6.83e-274	1	386	1	386
BCN29768.1	5.38e-271	1	386	1	386
CAB1239511.1	1.04e-268	1	386	1	386

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6MYV_A	9.80e-07	100	247	273	414	Sialidase26co-crystallized with DANA-Gc [bacterium],6MYV_B Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_C Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_D Sialidase26 co-crystallized with DANA-Gc [bacterium]
6MRV_A	1.01e-06	100	247	294	435	Sialidase26co-crystallized with DANA [bacterium],6MRV_B Sialidase26 co-crystallized with DANA [bacterium],6MRX_A Sialidase26 apo [bacterium],6MRX_B Sialidase26 apo [bacterium],6MRX_C Sialidase26 apo [bacterium],6MRX_D Sialidase26 apo [bacterium]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P31206	4.12e-06	121	308	308	494	Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000059	0.000004	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001015_00114.