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CAZyme Information: MGYG000001538_00150

You are here: Home > Sequence: MGYG000001538_00150

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Collinsella ihuae
Lineage Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Coriobacteriaceae; Collinsella; Collinsella ihuae
CAZyme ID MGYG000001538_00150
CAZy Family GH36
CAZyme Description Bifunctional alpha-galactosidase/sucrose kinase AgaSK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
731 MGYG000001538_2|CGC1 82015.44 4.745
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001538 2836446 Isolate not provided not provided
Gene Location Start: 27466;  End: 29661  Strand: +

Full Sequence      Download help

MPIRIDDATR  TFTLHTLHTT  YQMQVDEVGY  LTHLYYGARS  EGQMSYLPTF  ADRSGCCTTP60
HDVKDRTYSL  DVLPQEFPFQ  GNGDLRSPLL  VVRDAQGTFG  CDLRYARHEV  RCGKYALAGL120
PAAYADADAD  DAQTLSVTLA  DERLGLEVEL  LYGVLPAIDV  ICRAAVVKNR  SEGRVTVEKL180
QSACLDFVHG  NFDVITFNGQ  HCMERKPSRQ  RVLPGSFAVS  SRRGQSSHQY  NPFMILCDRD240
ATETAGRAWS  MTFVYSGNFK  AEVEQTQYQQ  IRMQMGLSDE  LFSYPLEPGD  ELVAPEVIMT300
YSGAGLERLS  HNLHRCIRRH  ICRGPWRDAP  RPVLVNSWEA  HYFNFTGDEL  VRLAAKAADL360
GMDMLVMDDG  WFGDRNDDFR  ALGDWSVNEE  KLGGTLAQLI  EKINALGIKF  GIWMEPEMVN420
EDSDLYRAHP  DWALAVPGKA  PALGRDQLVL  DFSREDVREN  IFAQICSVLD  QGNIEYLKWD480
FNRSMVDIYS  HAATDQGRVV  YDYYLGLYDV  LERLVQRYPN  LLIEGCAAGG  GRFDAGWLHY540
APQFWTSDNT  DGHDRMTIQY  GTSFGYPCST  MGAHVSACPN  EVNGRTVSLS  ARGLVAMAGG600
GFGYELDLLE  LPERACEIIR  NQIAQHRSIE  QLVREGLYYR  LTDPATDDIY  AWEFVSEDGA660
EAIVNAVVAR  AEGYGEARYV  VPRGLTPDAL  YREVNMDQVF  AANALMDMGL  PLPVSSALYM720
SRSFRFVRVD  A731

Enzyme Prediction      help

No EC number prediction in MGYG000001538_00150.

CAZyme Signature Domains help

Created with Snap367310914618221925529232836540243847551154858462165769412710GH36
Family Start End Evalue family coverage
GH36 12 710 7.6e-245 0.9941860465116279

CDD Domains      download full data without filtering help

Created with Snap367310914618221925529232836540243847551154858462165769423726GalA295636Melibiase330627GH3629287Glyco_hydro_36N651726Glyco_hydro_36C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3345 GalA 9.57e-168 23 726 13 679
Alpha-galactosidase [Carbohydrate transport and metabolism].
pfam02065 Melibiase 3.15e-160 295 636 5 347
Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
cd14791 GH36 8.77e-131 330 627 1 298
glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam16875 Glyco_hydro_36N 3.46e-97 29 287 1 256
Glycosyl hydrolase family 36 N-terminal domain. This domain is found at the N-terminus of many family 36 glycoside hydrolases. It has a beta-supersandwich fold.
pfam16874 Glyco_hydro_36C 7.51e-14 651 726 3 78
Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.

CAZyme Hits      help

Created with Snap36731091461822192552923283654024384755115485846216576941730AKT49114.1|GH361719QRT49300.1|GH361719QEK18307.1|GH367728CBL26995.1|GH367728QCU00892.1|GH36
Hit ID E-Value Query Start Query End Hit Start Hit End
AKT49114.1 0.0 1 730 1 728
QRT49300.1 1.28e-304 1 719 1 716
QEK18307.1 4.14e-298 1 719 1 716
CBL26995.1 3.79e-292 7 728 7 728
QCU00892.1 1.29e-289 7 728 7 725

PDB Hits      download full data without filtering help

Created with Snap367310914618221925529232836540243847551154858462165769417292YFN_A17304FNQ_A37302XN0_A17304FNR_A37302XN2_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2YFN_A 1.03e-278 1 729 1 720
galactosidasedomain of alpha-galactosidase-sucrose kinase, AgaSK [[Ruminococcus] gnavus E1],2YFO_A GALACTOSIDASE DOMAIN OF ALPHA-GALACTOSIDASE-SUCROSE KINASE, AGASK, in complex with galactose [[Ruminococcus] gnavus E1]
4FNQ_A 3.11e-199 1 730 1 728
Crystalstructure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
2XN0_A 5.61e-195 3 730 6 732
Structureof alpha-galactosidase from Lactobacillus acidophilus NCFM, PtCl4 derivative [Lactobacillus acidophilus NCFM],2XN0_B Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM, PtCl4 derivative [Lactobacillus acidophilus NCFM],2XN1_A Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM with TRIS [Lactobacillus acidophilus NCFM],2XN1_B Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM with TRIS [Lactobacillus acidophilus NCFM],2XN1_C Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM with TRIS [Lactobacillus acidophilus NCFM],2XN1_D Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM with TRIS [Lactobacillus acidophilus NCFM]
4FNR_A 7.20e-195 1 730 1 728
Crystalstructure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_B Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_C Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_D Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
2XN2_A 1.58e-194 3 730 6 732
Structureof alpha-galactosidase from Lactobacillus acidophilus NCFM with galactose [Lactobacillus acidophilus NCFM]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36731091461822192552923283654024384755115485846216576941729sp|G4T4R7|AGASK_RUMGN3730sp|G1UB44|MELA_LACAC1730sp|Q9ALJ4|AGAA_GEOSE3729sp|P43467|AGAL1_PEDPE75710sp|Q5AU92|AGALC_EMENI
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G4T4R7 8.76e-275 1 729 1 720
Bifunctional alpha-galactosidase/sucrose kinase AgaSK OS=Ruminococcus gnavus OX=33038 GN=agaSK PE=1 SV=1
G1UB44 3.07e-194 3 730 6 732
Alpha-galactosidase Mel36A OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=melA PE=1 SV=1
Q9ALJ4 3.94e-194 1 730 1 728
Alpha-galactosidase AgaA OS=Geobacillus stearothermophilus OX=1422 GN=agaA PE=1 SV=1
P43467 5.30e-184 3 729 4 730
Alpha-galactosidase 1 OS=Pediococcus pentosaceus OX=1255 GN=agaR PE=3 SV=1
Q5AU92 2.86e-154 75 710 97 732
Alpha-galactosidase C OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=aglC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000052 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001538_00150.