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CAZyme Information: MGYG000001958_00441

You are here: Home > Sequence: MGYG000001958_00441

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; Intestinimonas;
CAZyme ID MGYG000001958_00441
CAZy Family GH36
CAZyme Description Bifunctional alpha-galactosidase/sucrose kinase AgaSK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
727 81766.36 5.764
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001958 1726878 MAG Denmark Europe
Gene Location Start: 661;  End: 2844  Strand: +

Full Sequence      Download help

MIGYDASQRT  ITLNTRSTSY  QMKIDGTGVL  LHTYYGPRLR  RGDLSRLICP  EDRGFSPNPD60
EVGLDRTWSL  DTQPQEYSSS  GVGDFRLPSL  EADLADGSHT  ADFRYVRHTV  TEGKYALEGL120
PAFYGDGVTA  QTLTVELHDR  CSGLTVELLY  GVLEEYDMIT  RAVRVRNDGA  TPVRLTRVAS180
ACLDFPVGEH  DFITLGGAYA  REREPVRAAL  TQGVHSAGSV  RGSSSHQQNP  FLVLCDRDTT240
EDAGRCWAMA  LVYSGNFLAS  VEHTQFHETR  MTLGIHPFHF  AWRLEPGETF  TAPEAAMVFS300
ARGLGHMSRL  FHRAIRLNLC  RGPWKDQRRP  ILINNWEATL  FHFDADKIFS  IAQAASRVGV360
EMMVMDDGWF  GERNDDFGGL  GDWNVNQKKL  PGGLAPLAER  INGLGMKFGL  WVEPEMVNEN420
SDLYRAHPDW  AFQVPGRPLT  RGRYQLVLDL  TRPEVKQYVL  DNLRSTLKSA  PIAYVKWDMN480
RSLTDVWSAA  LPAQRQGEVY  HRFVLAVYEI  LEALHREFPD  LLIEGCSGGG  GRFDCGMLYY540
TPQIWCSDNT  DAMDRLRIQY  GTSFCYPCCT  MGAHVSAVPN  GLTHRSTPFH  TRGVVAAAGT600
FGYELDLNEL  TTEELDQVRE  QIAAFRTDWE  LVMRGDYYRL  GDPFRAEEPF  CAWMHVAPDK660
SRALVGLVQT  QRHANPIRPL  LRLKGLDPDR  DYRVNGQVYG  GDELMYAGLA  LPFLDECEAV720
QYHIEAV727

Enzyme Prediction      help

EC 3.2.1.22

CAZyme Signature Domains help

Created with Snap367210914518121825429032736339943647250854558161765469011710GH36
Family Start End Evalue family coverage
GH36 11 710 5.1e-267 0.9956395348837209

CDD Domains      download full data without filtering help

Created with Snap367210914518121825429032736339943647250854558161765469013716GalA289635Melibiase328627GH3628285Glyco_hydro_36N651724Glyco_hydro_36C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3345 GalA 0.0 13 716 6 672
Alpha-galactosidase [Carbohydrate transport and metabolism].
pfam02065 Melibiase 0.0 289 635 1 347
Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
cd14791 GH36 3.39e-138 328 627 1 299
glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam16875 Glyco_hydro_36N 9.18e-112 28 285 1 256
Glycosyl hydrolase family 36 N-terminal domain. This domain is found at the N-terminus of many family 36 glycoside hydrolases. It has a beta-supersandwich fold.
pfam16874 Glyco_hydro_36C 1.05e-24 651 724 2 78
Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.

CAZyme Hits      help

Created with Snap36721091451812182542903273633994364725085455816176546902727QIX93423.1|GH362727ANU49477.1|GH362727QQR01604.1|GH362727QRP38527.1|GH362727ASN96678.1|GH36
Hit ID E-Value Query Start Query End Hit Start Hit End
QIX93423.1 2.91e-274 2 727 3 733
ANU49477.1 1.67e-273 2 727 3 733
QQR01604.1 1.67e-273 2 727 3 733
QRP38527.1 9.55e-273 2 727 3 733
ASN96678.1 9.55e-273 2 727 3 733

PDB Hits      download full data without filtering help

Created with Snap367210914518121825429032736339943647250854558161765469027134FNQ_A47222YFN_A27134FNR_A27134FNU_A27134FNT_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FNQ_A 1.45e-249 2 713 3 712
Crystalstructure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
2YFN_A 8.62e-249 4 722 5 715
galactosidasedomain of alpha-galactosidase-sucrose kinase, AgaSK [[Ruminococcus] gnavus E1],2YFO_A GALACTOSIDASE DOMAIN OF ALPHA-GALACTOSIDASE-SUCROSE KINASE, AGASK, in complex with galactose [[Ruminococcus] gnavus E1]
4FNR_A 3.82e-247 2 713 3 712
Crystalstructure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_B Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_C Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_D Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNU_A 3.54e-245 2 713 3 712
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus]
4FNT_A 5.01e-245 2 713 3 712
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36721091451812182542903273633994364725085455816176546902713sp|Q9ALJ4|AGAA_GEOSE4722sp|G4T4R7|AGASK_RUMGN1727sp|G1UB44|MELA_LACAC1727sp|P43467|AGAL1_PEDPE2713sp|Q9UUZ4|AGALC_ASPNG
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9ALJ4 2.09e-246 2 713 3 712
Alpha-galactosidase AgaA OS=Geobacillus stearothermophilus OX=1422 GN=agaA PE=1 SV=1
G4T4R7 5.91e-245 4 722 5 715
Bifunctional alpha-galactosidase/sucrose kinase AgaSK OS=Ruminococcus gnavus OX=33038 GN=agaSK PE=1 SV=1
G1UB44 1.90e-216 1 727 5 731
Alpha-galactosidase Mel36A OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=melA PE=1 SV=1
P43467 3.40e-209 1 727 3 730
Alpha-galactosidase 1 OS=Pediococcus pentosaceus OX=1255 GN=agaR PE=3 SV=1
Q9UUZ4 2.31e-176 2 713 26 733
Alpha-galactosidase C OS=Aspergillus niger OX=5061 GN=aglC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000026 0.000003 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001958_00441.