You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001681_00181
You are here: Home > Sequence: MGYG000001681_00181
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Ruminococcus sp900761275 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus; Ruminococcus sp900761275 | |||||||||||
| CAZyme ID | MGYG000001681_00181 | |||||||||||
| CAZy Family | GH44 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 12195; End: 14396 Strand: + | |||||||||||
Full Sequence Download help
| MKRILTTVTS VLLMSTFTAP VKPVSAGDSY DLNVTVDTTG YRRSISPYIY GINNSRSGEI | 60 |
| PPVTTFSARQ GGNRFSAYNW ETNASSAGAD YKHYSDAYLI NFNKEKLEIP GSTALDFARD | 120 |
| MAAQNTDYKI TTLQMAGYVS ADMNGEVTDE EVAPSDRWIP VKASKNAPFS LVPDKEDNCV | 180 |
| YMDEYVNYLV QTLGDSGTKT GIQGYCLDNE PSIWSGTHKR MHPEKTTCKE IISKSIEFAS | 240 |
| AVKSVDPGAE IYGGVMYGFN AYRSFNNAVD WETVGKDYNW FISYYLDEMA KAEKQNGRRL | 300 |
| IDVLDLHYYS EAKGQERVTF CQDYTHTDCI EARLQAPRSL WDATYTENSW IGQYNERFLP | 360 |
| LMPLINQSIE QYYPGTKLSF TEYSFGGGGH ISGAIAEADA LGIFAEYGVY MANNWAVASD | 420 |
| ESYTHAAMNL YTNYDGNGAK FGDTLVQAER SDIEKSSVYA SINGTDESKL NVVLMNKSQT | 480 |
| DKQNANIQIT SGADYDSAKV YGITSDSSEI KLLQTVTGIK DNKFTLELPA LSVVQIELTD | 540 |
| DGYSMPGDVN MDETVNVEDV RLLQDWLLAK PDVQLKNWEA ADLYKDNMLD AFDLCLLKRM | 600 |
| IVKWNTEIIL PTEISFIQTK TAQWKIRNGC AEKTVQCTFK GTPGNTLNMA FGYWNPVIAN | 660 |
| EDGTTGKWFN NEDTRLGEYT FDETGTAVIT FTVPKDAINV ELITFNHTVM QDGYKVQLEK | 720 |
| EGFTLEQVVI LNT | 733 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH44 | 30 | 539 | 1e-180 | 0.9922178988326849 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam12891 | Glyco_hydro_44 | 1.10e-67 | 85 | 312 | 1 | 234 | Glycoside hydrolase family 44. This is a family of bacterial glycoside hydrolases formerly known as cellulase family J, and now known as Cel44A. It is one of the major enzymatic components of the cellulosome of Clostridium thermocellum strain F1 and of many other Firmicutes. |
| cd14256 | Dockerin_I | 4.13e-13 | 546 | 602 | 1 | 57 | Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex. |
| pfam00404 | Dockerin_1 | 2.09e-06 | 547 | 601 | 1 | 55 | Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BAV13029.1 | 1.36e-181 | 24 | 568 | 30 | 574 |
| ADL53320.1 | 1.36e-181 | 24 | 568 | 30 | 574 |
| QNU68763.1 | 4.04e-178 | 32 | 568 | 34 | 570 |
| ADZ19966.1 | 1.75e-176 | 28 | 567 | 31 | 571 |
| AEI34285.1 | 1.75e-176 | 28 | 567 | 31 | 571 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2E0P_A | 4.29e-180 | 32 | 538 | 10 | 514 | ChainA, Endoglucanase [Acetivibrio thermocellus],2E4T_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EO7_A Chain A, Endoglucanase [Acetivibrio thermocellus] |
| 2EEX_A | 1.21e-179 | 32 | 538 | 10 | 514 | ChainA, Endoglucanase [Acetivibrio thermocellus],2EJ1_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EQD_A Chain A, Endoglucanase [Acetivibrio thermocellus] |
| 3IK2_A | 1.21e-173 | 31 | 538 | 2 | 509 | CrystalStructure of a Glycoside Hydrolase Family 44 Endoglucanase produced by Clostridium acetobutylium ATCC 824 [Clostridium acetobutylicum ATCC 824] |
| 2YIH_A | 1.68e-158 | 32 | 546 | 10 | 523 | Structureof a Paenibacillus polymyxa Xyloglucanase from GH family 44 with Xyloglucan [Paenibacillus polymyxa],2YJQ_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],2YJQ_B Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa] |
| 2YKK_A | 8.48e-156 | 32 | 539 | 10 | 516 | Structureof a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],3ZQ9_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P29719 | 1.42e-160 | 16 | 559 | 20 | 559 | Endoglucanase A OS=Paenibacillus lautus OX=1401 GN=celA PE=3 SV=1 |
| P22533 | 6.23e-151 | 32 | 539 | 788 | 1303 | Beta-mannanase/endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=manA PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000459 | 0.998467 | 0.000408 | 0.000223 | 0.000202 | 0.000182 |