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CAZyme Information: MGYG000001015_00039

You are here: Home > Sequence: MGYG000001015_00039

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Gemmiger sp900556255
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Gemmiger; Gemmiger sp900556255
CAZyme ID MGYG000001015_00039
CAZy Family GH67
CAZyme Description Xylan alpha-(1->2)-glucuronosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
652 MGYG000001015_2|CGC1 73314.56 5.1928
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001015 1427844 MAG United Kingdom Europe
Gene Location Start: 15501;  End: 17459  Strand: +

Full Sequence      Download help

MAFTKCWLAY  PEIRGCHCDA  ISLHTELTGE  TIDRAKAELA  EGFKGLYGAA  LTEGDDITLA60
LDMALDPEGY  RLKAADGHCT  IEGGSEVGVL  YGVFALLRNL  QTAGKAWAQF  TADEEKAPSN120
RLRMLNHWDN  MDGSIERGYS  GDSFFFKDSE  ILIDVPRLTA  YARMLASVGI  NGITINNVNV180
KDAASWLITD  RYFGALQEYL  KIFTPYGVKL  YLSINFAAPM  ELGGMDSADP  CDPAVAKWWA240
DKAQEVWANL  PGLGGFLVKA  DSEGRPGPFT  YGRNQADGAN  MLADAVAPCG  GHIVWRCFVY300
NCQQDWRNTK  IDRARAGYDY  FMPLDGTFRD  NVTLQIKNGP  MDFQVREPVS  PLIGGLQHTH360
IAVEFQIAQE  YTGQQRHVCY  LMPWFRQILD  FDMHTRPNGD  AHVRALIQGA  GNGMVAVTNT420
GNDENWTGHD  LAAANLYGFG  RLSYDTTLDP  AVIAGEWLRL  TFGNNEPVEK  TLHRILMQSW480
PTYEKYNAPL  GVGWMVNPNY  HYGPNVDGYE  YSRWGCYHRA  SFDGIGIDRS  PTGSDYCHQY540
APELAEMYAN  VETCPEELLL  FFHHMPYNYV  LKSGKTILQH  IYDTHFEGAE  DAARFYDEVV600
TLKPYLDPAV  YARLEARFAH  QKEHACEWRD  VINTYFYRKT  GIGDAHGRKI  YE652

Enzyme Prediction      help

EC 3.2.1.139 3.2.1.131

CAZyme Signature Domains help

Created with Snap3265971301631952282602933263583914234564895215545866195648GH67
Family Start End Evalue family coverage
GH67 5 648 1.9e-257 0.9940209267563528

CDD Domains      download full data without filtering help

Created with Snap3265971301631952282602933263583914234564895215545866196651AguA2111425Glyco_hydro_67M427649Glyco_hydro_67C696Glyco_hydro_67N2093Glyco_hydro_20b
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3661 AguA2 0.0 6 651 10 682
Alpha-glucuronidase [Carbohydrate transport and metabolism].
pfam07488 Glyco_hydro_67M 0.0 111 425 10 324
Glycosyl hydrolase family 67 middle domain. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the central catalytic domain of alpha-glucuronidase.
pfam07477 Glyco_hydro_67C 2.93e-128 427 649 1 223
Glycosyl hydrolase family 67 C-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the C terminal region of alpha-glucuronidase which is mainly alpha-helical. It wraps around the catalytic domain (pfam07488), making additional interactions both with the N-terminal domain (pfam03648) of its parent monomer and also forming the majority of the dimer-surface with the equivalent C-terminal domain of the other monomer of the dimer.
pfam03648 Glyco_hydro_67N 6.00e-09 6 96 1 120
Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).
pfam02838 Glyco_hydro_20b 3.16e-05 20 93 19 101
Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.

CAZyme Hits      help

Created with Snap3265971301631952282602933263583914234564895215545866191469CCG34873.1|GH671651QHQ60902.1|GH673651QJU15649.1|GH673651QQQ91839.1|GH673651ASU31294.1|GH67
Hit ID E-Value Query Start Query End Hit Start Hit End
CCG34873.1 0.0 1 469 1 469
QHQ60902.1 1.76e-287 1 651 1 672
QJU15649.1 5.33e-279 3 651 5 661
QQQ91839.1 5.33e-279 3 651 5 661
ASU31294.1 5.33e-279 3 651 5 661

PDB Hits      download full data without filtering help

Created with Snap326597130163195228260293326358391423456489521554586619676511MQP_A676511MQR_A676511K9D_A676511K9E_A236411GQI_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1MQP_A 4.22e-242 67 651 88 678
TheCrystal Structure Of Alpha-D-Glucuronidase From Bacillus Stearothermophilus T-6 [Geobacillus stearothermophilus]
1MQR_A 1.20e-241 67 651 88 678
ChainA, ALPHA-D-GLUCURONIDASE [Geobacillus stearothermophilus]
1K9D_A 2.41e-241 67 651 88 678
The1.7 A crystal structure of alpha-D-glucuronidase, a family-67 glycoside hydrolase from Bacillus stearothermophilus T-1 [Geobacillus stearothermophilus],1L8N_A The 1.5A crystal structure of alpha-D-glucuronidase from Bacillus stearothermophilus T-1, complexed with 4-O-methyl-glucuronic acid and xylotriose [Geobacillus stearothermophilus],1MQQ_A THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE FROM BACILLUS STEAROTHERMOPHILUS T-1 COMPLEXED WITH GLUCURONIC ACID [Geobacillus stearothermophilus]
1K9E_A 2.41e-241 67 651 88 678
ChainA, alpha-D-glucuronidase [Geobacillus stearothermophilus],1K9F_A Chain A, alpha-D-glucuronidase [Geobacillus stearothermophilus]
1GQI_A 3.18e-144 23 641 29 668
Structureof Pseudomonas cellulosa alpha-D-glucuronidase [Cellvibrio japonicus],1GQI_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase [Cellvibrio japonicus],1GQJ_A Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with xylobiose [Cellvibrio japonicus],1GQJ_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with xylobiose [Cellvibrio japonicus],1GQK_A Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid [Cellvibrio japonicus],1GQK_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid [Cellvibrio japonicus],1GQL_A Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid and xylotriose [Cellvibrio japonicus],1GQL_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid and xylotriose [Cellvibrio japonicus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap32659713016319522826029332635839142345648952155458661967651sp|Q09LY5|AGUA_GEOSE55651sp|P96105|AGUA_THEMA7648sp|Q0CJP9|AGUA_ASPTN65648sp|A1CC12|AGUA_ASPCL7648sp|Q5AQZ4|AGUA_EMENI
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q09LY5 2.31e-241 67 651 88 678
Xylan alpha-(1->2)-glucuronosidase OS=Geobacillus stearothermophilus OX=1422 GN=aguA PE=1 SV=1
P96105 4.97e-224 55 651 73 673
Xylan alpha-(1->2)-glucuronosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=aguA PE=1 SV=2
Q0CJP9 2.76e-165 7 648 26 693
Probable alpha-glucuronidase A OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=aguA PE=3 SV=1
A1CC12 7.54e-165 65 648 110 692
Probable alpha-glucuronidase A OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=aguA PE=3 SV=1
Q5AQZ4 1.83e-164 7 648 24 699
Alpha-glucuronidase A OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=aguA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000034 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001015_00039.