You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001659_00291
You are here: Home > Sequence: MGYG000001659_00291
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Paraprevotella sp900760455 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella; Paraprevotella sp900760455 | |||||||||||
| CAZyme ID | MGYG000001659_00291 | |||||||||||
| CAZy Family | GH84 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 110668; End: 113550 Strand: - | |||||||||||
Full Sequence Download help
| MRIKTLASLG LLVGSLGLTA NAQTATISPI PQSAEWGTKA FDKTTSFTLT GAETADPDAV | 60 |
| NVLKKHFTTT GGDIEIIIGE RGDEAVAAYG NLIPEKNEGY YLKVEPGKVI IAGNDEQGTF | 120 |
| YGVQSFLQVA AQPEVMSVTV TDWPMTIKRG VIEGFYGNPW SFEDRKSQFE FYGANKMNIY | 180 |
| IYGPKDDVYH HSRWYEPYPE AEARRMQELV KCATDNKVKF VWAMHPSNSI TSDSDKQKAL | 240 |
| AKFEQMYGLG VRAFAIFFDD ISANSVNDQV AYLNFLTDEF VNKKGDVESM IVCPTQYNKA | 300 |
| WSGGDYLSIM GAQLYPEIEI MWTGNSVCDM IQKTDTDWIK GQTGRKPFIW LNYPVNDYGQ | 360 |
| HNLLMGPLVD NGTDIYDQVS AFCSNPMQYA EASKVVLYSI ADYTWNPSAF EPLPAWDRAI | 420 |
| AYLMPEHAEA FDIFCKSNVD VASSVHGLRI YHETPEFKSL IEKHTELVNS ETAAALAAYF | 480 |
| AKTRAAAEEL LALEGESAMV DEIKEFLQYF HYQAIRGEKI AEMSAALIDN KPENFIEAYT | 540 |
| EYKTADESAD QLVSRDFQGS IQSVKPHTAT LYVEPFIKKS ILELVTLFKE SGAEYPDDLF | 600 |
| PKMLLENGTY FIKVNGKYLT NLAGSSMPTF QTEVDDINEG RQRWMISLDI TTERYKILNE | 660 |
| WDKRYINEYG VFSAGENNPY EAIWHTYNLY RMNGKYAIQN AGRSGDKFWT ANNTRISQSS | 720 |
| SNELKYSNFI FEIIPTSGPA EHPVITDGKT DFYYIMDAEG RCLTNTNPNK SGGNPTFKPR | 780 |
| ETPAVRSQLW TFSIDNASGR FKILNASDNR YINELGNFGT NAYDAAWNSY TMTEFDGLFS | 840 |
| IQNGGEAGTN YWYINGDRIS KKEMDRSESY QFRIVHYKNA TGISNPAAKD ADIDIVVEGG | 900 |
| KVIVKSASAV KSITVNSLDG KKMAESKNSP ELTISNLPRN TYIVNAVCAD GQQTAKIQLP | 960 |
| 960 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH84 | 149 | 435 | 2.5e-100 | 0.9932203389830508 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam07555 | NAGidase | 2.75e-143 | 149 | 434 | 1 | 293 | beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity. |
| pfam02838 | Glyco_hydro_20b | 1.06e-13 | 29 | 142 | 6 | 123 | Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold. |
| pfam03648 | Glyco_hydro_67N | 0.009 | 68 | 123 | 56 | 117 | Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488). |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QFQ13183.1 | 8.78e-233 | 4 | 738 | 3 | 737 |
| QUB43766.1 | 1.19e-144 | 78 | 735 | 73 | 736 |
| QKH86239.1 | 1.34e-128 | 1 | 594 | 1 | 607 |
| QRM68690.1 | 1.88e-128 | 1 | 594 | 1 | 607 |
| QCQ48131.1 | 1.88e-128 | 1 | 594 | 1 | 607 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2VVN_A | 3.73e-128 | 18 | 607 | 17 | 619 | BtGH84in complex with NH-Butylthiazoline [Bacteroides thetaiotaomicron VPI-5482],2VVN_B BtGH84 in complex with NH-Butylthiazoline [Bacteroides thetaiotaomicron VPI-5482],2VVS_A BtGH84 structure in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482],2X0H_A BtGH84 Michaelis complex [Bacteroides thetaiotaomicron VPI-5482],2X0H_B BtGH84 Michaelis complex [Bacteroides thetaiotaomicron VPI-5482],4AIS_A A complex structure of BtGH84 [Bacteroides thetaiotaomicron VPI-5482],4AIS_B A complex structure of BtGH84 [Bacteroides thetaiotaomicron VPI-5482],7OU8_AAA Chain AAA, O-GlcNAcase BT_4395 [Bacteroides thetaiotaomicron VPI-5482],7OU8_BBB Chain BBB, O-GlcNAcase BT_4395 [Bacteroides thetaiotaomicron VPI-5482] |
| 7K41_A | 1.72e-127 | 22 | 607 | 3 | 601 | ChainA, O-GlcNAcase BT_4395 [Escherichia coli K-12] |
| 2WZI_A | 2.01e-127 | 18 | 607 | 17 | 619 | BtGH84D243N in complex with 5F-oxazoline [Bacteroides thetaiotaomicron VPI-5482],2WZI_B BtGH84 D243N in complex with 5F-oxazoline [Bacteroides thetaiotaomicron VPI-5482] |
| 2WZH_A | 2.01e-127 | 18 | 607 | 17 | 619 | BtGH84D242N in complex with MeUMB-derived oxazoline [Bacteroides thetaiotaomicron VPI-5482],4AIU_A A complex structure of BtGH84 [Bacteroides thetaiotaomicron VPI-5482] |
| 2J47_A | 2.21e-127 | 23 | 607 | 1 | 598 | Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with a imidazole-pugnac hybrid inhibitor [Bacteroides thetaiotaomicron VPI-5482],2W4X_A BtGH84 in complex with STZ [Bacteroides thetaiotaomicron VPI-5482],2W66_A BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W66_B BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W67_A BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2W67_B BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2WCA_A BtGH84 in complex with n-butyl pugnac [Bacteroides thetaiotaomicron VPI-5482],2XJ7_A BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XJ7_B BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XM1_A BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM1_B BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM2_A BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],2XM2_B BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],4UR9_A Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],4UR9_B Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],5FKY_A Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FKY_B Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FL0_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL0_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q89ZI2 | 2.04e-127 | 18 | 607 | 17 | 619 | O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1 |
| Q0TR53 | 4.01e-89 | 27 | 503 | 46 | 558 | O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1 |
| Q8XL08 | 1.04e-88 | 27 | 503 | 46 | 558 | O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1 |
| P26831 | 6.65e-42 | 95 | 406 | 129 | 464 | Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2 |
| O60502 | 5.85e-36 | 150 | 408 | 63 | 334 | Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000237 | 0.999069 | 0.000170 | 0.000180 | 0.000160 | 0.000139 |