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CAZyme Information: MGYG000004830_00123

You are here: Home > Sequence: MGYG000004830_00123

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-485 sp900549375
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-485; CAG-485 sp900549375
CAZyme ID MGYG000004830_00123
CAZy Family GH84
CAZyme Description O-GlcNAcase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
593 MGYG000004830_1|CGC1 67272.52 5.7738
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004830 2642212 MAG China Asia
Gene Location Start: 157325;  End: 159106  Strand: -

Full Sequence      Download help

MRFPVYIALL  FAASIAISPV  YGAKKSLPDT  LPVPGKVLDH  EGIPLNPTPV  AVSHPYSGIL60
NLSAGISTSE  IPAEMRGALS  GIKQSACGIP  VKISIDKNSL  AKSKPGTYRL  EIGPDQISIA120
GYDDDGIYYG  LQTLRNIIEE  IEKSDKDDLP  MMVVDDYPEF  KYRGVVEGFY  GRPWSHETRL180
SLIDFMGRNK  MNSYVYGPKD  DPYHRTPDWR  KPYPAEEGKK  IKELAERCRK  NRMRFVWAIH240
PGGDIRWDKA  DYDSLLNKFE  SMYDLGVRQF  AVFFDDIKGE  GTDSKKQAAL  LNSLVRDFVR300
KKGDVGNLIV  CPTDYNQGWA  NPSEKGQLAV  YGRELDPEVE  VFWTGKVVCG  DIENESLEFV360
DSRINRPALV  WWNFPVTDYC  RHNLLLGPVY  GLETTLDSSK  MAGIESNPME  NGEASKGAIY420
GVADYAWNPS  AYNPLDNWNR  SFHVLMPGAS  EEYATFAIHS  ADPPKNYRRN  ESWNVKTFSY480
NNYTPEMFEA  LRKEFQAISE  APGKMFDKGE  NIPLLVEIAP  WLVEFENLGK  RGLMALDLIK540
TYERGDKEKF  EKDYRKLKLI  NDIQRPGYLD  HRSGTLKLQP  FIDNVLKELK  EKI593

Enzyme Prediction      help

No EC number prediction in MGYG000004830_00123.

CAZyme Signature Domains help

Created with Snap295988118148177207237266296326355385415444474504533563163457GH84
Family Start End Evalue family coverage
GH84 163 457 3.8e-106 0.9932203389830508

CDD Domains      download full data without filtering help

Created with Snap295988118148177207237266296326355385415444474504533563163456NAGidase47156Glyco_hydro_20b20218Chb
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam07555 NAGidase 6.48e-160 163 456 1 293
beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam02838 Glyco_hydro_20b 1.54e-07 47 156 6 123
Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
COG3525 Chb 3.14e-06 20 218 100 317
N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism].

CAZyme Hits      help

Created with Snap29598811814817720723726629632635538541544447450453356329589BCI62100.1|GH848589BBL05673.1|GH8429589AHF11939.1|GH8433589ADV43394.1|GH8432589ASB38050.1|GH84
Hit ID E-Value Query Start Query End Hit Start Hit End
BCI62100.1 1.58e-216 29 589 41 604
BBL05673.1 1.76e-210 8 589 7 597
AHF11939.1 4.81e-210 29 589 39 602
ADV43394.1 7.50e-208 33 589 42 601
ASB38050.1 2.91e-205 32 589 45 602

PDB Hits      download full data without filtering help

Created with Snap295988118148177207237266296326355385415444474504533563755935MI4_A755932J4G_A755932J47_A755932CHO_A755932JIW_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MI4_A 1.49e-148 75 593 52 576
BtGH84mutant with covalent modification by MA3 [Bacteroides thetaiotaomicron VPI-5482],5MI5_A BtGH84 mutant with covalent modification by MA3 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482],5MI6_A BtGH84 mutant with covalent modification by MA3 in complex with Thiamet G [Bacteroides thetaiotaomicron VPI-5482],5MI7_A BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482]
2J4G_A 2.09e-148 75 593 40 564
Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482],2J4G_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482]
2J47_A 2.16e-148 75 593 41 565
Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with a imidazole-pugnac hybrid inhibitor [Bacteroides thetaiotaomicron VPI-5482],2W4X_A BtGH84 in complex with STZ [Bacteroides thetaiotaomicron VPI-5482],2W66_A BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W66_B BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W67_A BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2W67_B BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2WCA_A BtGH84 in complex with n-butyl pugnac [Bacteroides thetaiotaomicron VPI-5482],2XJ7_A BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XJ7_B BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XM1_A BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM1_B BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM2_A BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],2XM2_B BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],4UR9_A Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],4UR9_B Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],5FKY_A Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FKY_B Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FL0_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL0_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron]
2CHO_A 2.16e-148 75 593 41 565
Bacteroidesthetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482],2CHO_B Bacteroides thetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482]
2JIW_A 2.16e-148 75 593 41 565
Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with 2- Acetylamino-2-deoxy-1-epivalienamine [Bacteroides thetaiotaomicron VPI-5482],2JIW_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with 2- Acetylamino-2-deoxy-1-epivalienamine [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Created with Snap29598811814817720723726629632635538541544447450453356375593sp|Q89ZI2|OGA_BACTN108551sp|Q0TR53|OGA_CLOP1108551sp|Q8XL08|OGA_CLOPE61530sp|P26831|NAGH_CLOPE164433sp|O60502|OGA_HUMAN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q89ZI2 2.17e-147 75 593 62 586
O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
Q0TR53 1.30e-89 108 551 133 584
O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Q8XL08 3.47e-89 108 551 133 584
O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
P26831 1.44e-54 61 530 85 555
Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
O60502 1.14e-37 164 433 63 337
Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000240 0.999160 0.000153 0.000149 0.000137 0.000126

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004830_00123.