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CAZyme Information: MGYG000001908_00090

You are here: Home > Sequence: MGYG000001908_00090

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Ruminococcus_D sp900543145
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus_D; Ruminococcus_D sp900543145
CAZyme ID MGYG000001908_00090
CAZy Family GH94
CAZyme Description Cellobiose phosphorylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
816 92193.28 4.8841
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001908 2355088 MAG Denmark Europe
Gene Location Start: 96631;  End: 99081  Strand: +

Full Sequence      Download help

MKFGFFDDVN  KEYVITNPKT  PYPWINYLGT  QEFFSLISNT  AGGYHFFKDA  RLRRITRYRY60
NNVPVDMGGR  YFYINDGDTI  WSPGWSPVKT  ELDAYSCRHG  MGYTIIKGEK  NGIEAEVTFF120
VPQNFNGEVQ  KVVLKNTSDK  SKSFKLFSFI  EWCLWNAQDD  STNFQRNFNT  GEVEIEGSTI180
YHKTEYKERR  DHFAFYTVNA  DICGFDTDRE  SFIGLYNGFE  NPQAVAAGKA  NNSVADGWSP240
IASHCLDMTL  GAGEEKTLVF  LLGYVENGAD  KWNADGSMNK  SKAYEMIESM  NTAEKADKAL300
AELKETWDAL  LSQYHVETGD  DKLNRMVNIW  NQYQCMVTFN  MSRSASYFES  GIGRGMGFRD360
SNQDLLGFVH  QIPERARERI  LDLAATQLED  GGCYHQYQPL  TKKGNNEIGG  DFSDDPLWMI420
LSTAQYIKET  GDYSILDEMV  PYDNDESKAQ  TMMHHLKQSF  WHVAKFVGPH  GLPLAMRADW480
NDCLNLSCHS  DIPGESFQTY  TSPKYGEDKF  SRVAESVMVA  AMMSFIGPEY  VALCKFKGLE540
EEASTAQSEI  DKMNENTMKY  GWDGEWFLRA  YDDFGNKVGS  HECEEGKIFI  EPQGFAVMGG600
LGKDSGKDIL  TLNSVKKYLD  SKYGLVLNNP  AFTKYYKEYG  EISTYPGGYK  ENAGIFCHNN660
AWIICAEAAI  GRGDQAFEYY  SKIAPAYLEE  ISDLHRTEPY  VYAQMIAGKD  AGRHGEAKNS720
WLTGTAAWNF  VAVSQYILGI  IPDYDGLKVD  PSIPEAWDGY  KLTRKFRGNT  YNITFKNPDH780
VSKGVKSVTV  DGVKINGNVL  PVFDEGTVHE  VEVVLG816

Enzyme Prediction      help

EC 2.4.1.20 2.4.1.49

CAZyme Signature Domains help

Created with Snap40811221632042442853263674084484895305716126526937347752813GH94
Family Start End Evalue family coverage
GH94 2 813 2.3e-303 0.7461389961389961

CDD Domains      download full data without filtering help

Created with Snap40811221632042442853263674084484895305716126526937347751302GH94N_CBP_like307740Glyco_hydro_361816COG345921263Glyco_transf_361302GH94N_ChBP_like
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11754 GH94N_CBP_like 0.0 1 302 1 303
N-terminal domain of cellobiose phosphorylase (CBP) and similar proteins. The glycoside hydrolase family 94 (previously known as glycosyltransferase family 36) includes cellobiose phosphorylase (EC:2.4.1.20) or cellobiose:phosphate alpha-D-glucosyltransferase, or CepA. This N-terminal domain is involved in oligomerization and may play a role in catalysis, but it is separate from the catalytic domain [an (alpha/alpha)(6) barrel]. Cellobiose phosphorylase participates in the degradation of cellulose, it catalyzes the phosphate dependent hydrolysis of cellobiose into alpha-D-glucose-1-phosphate and D-glucose, a reversible reaction.
pfam17167 Glyco_hydro_36 0.0 307 740 2 424
Glycosyl hydrolase 36 superfamily, catalytic domain. This is the catalytic region of the superfamily of enzymes referred to as GH36. UniProtKB:Q76IQ9 is a chitobiose phosphorylase that catalyzes the reversible phosphorolysis of chitobiose into alpha-GlcNAc-1-phosphate and GlcNAc with inversion of the anomeric configuration. The full-length enzyme comprises a beta sandwich domain and an (alpha/alpha)(6) barrel domain. The alpha-helical barrel component of the domain, this family, is the catalytic region.
COG3459 COG3459 0.0 1 816 271 1054
Cellobiose phosphorylase [Carbohydrate transport and metabolism].
pfam06165 Glyco_transf_36 1.76e-108 21 263 1 247
Glycosyltransferase family 36. The glycosyltransferase family 36 includes cellobiose phosphorylase (EC:2.4.1.20), cellodextrin phosphorylase (EC:2.4.1.49), chitobiose phosphorylase (EC:2.4.1.-). Many members of this family contain two copies of this domain.
cd11755 GH94N_ChBP_like 4.51e-101 1 302 1 300
N-terminal domain of chitobiose phosphorylase (ChBP) and similar proteins. The glycoside hydrolase family 94 (previously known as glycosyltransferase family 36) includes chitobiose phosphorylase (EC:2.4.1.-). This N-terminal domain is involved in oligomerization and may play a role in catalysis, but it is separate from the catalytic domain [an (alpha/alpha)(6) barrel]. Chitobiose phosphorylase catalyzes the reversible phosphate dependent hydrolysis of chitobiose [(GlcNAc)2] into alpha-GlcNAc-1-phosphate and GlcNAc. In some organisms, ChBP may be involved in the production of GlcNac-6-phosphate in intracellular pathways.

CAZyme Hits      help

Created with Snap40811221632042442853263674084484895305716126526937347751816CCO05478.1|GH941816ADU20744.1|GH94|2.4.1.201816CBL33370.1|GH941816CBK97022.1|GH941816ADU75001.1|GH94
Hit ID E-Value Query Start Query End Hit Start Hit End
CCO05478.1 0.0 1 816 1 819
ADU20744.1 0.0 1 816 1 827
CBL33370.1 0.0 1 816 1 833
CBK97022.1 0.0 1 816 1 833
ADU75001.1 0.0 1 816 1 811

PDB Hits      download full data without filtering help

Created with Snap408112216320424428532636740844848953057161265269373477518132CQS_A18133ACS_A18133ACT_A18133AFJ_A18163QDE_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2CQS_A 0.0 1 813 21 840
CrystalStructure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Ammonium Sulfate [Cellulomonas gilvus],2CQS_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Ammonium Sulfate [Cellulomonas gilvus],2CQT_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Sodium/Potassium Phosphate [Cellulomonas gilvus],2CQT_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Sodium/Potassium Phosphate [Cellulomonas gilvus],3QFY_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and Isofagomine [Cellulomonas gilvus],3QFY_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and Isofagomine [Cellulomonas gilvus],3QFZ_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and 1-Deoxynojirimycin [Cellulomonas gilvus],3QFZ_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and 1-Deoxynojirimycin [Cellulomonas gilvus],3QG0_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Phosphate and 1-Deoxynojirimycin [Cellulomonas gilvus],3QG0_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Phosphate and 1-Deoxynojirimycin [Cellulomonas gilvus]
3ACS_A 0.0 1 813 21 840
CrystalStructure of Cellvibrio gilvus Cellobiose Phosphorylase W488F mutant [Cellulomonas gilvus ATCC 13127],3ACS_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase W488F mutant [Cellulomonas gilvus ATCC 13127]
3ACT_A 0.0 1 813 21 840
CrystalStructure of Cellvibrio gilvus Cellobiose Phosphorylase Histidine mutant [Cellulomonas gilvus ATCC 13127],3ACT_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Histidine mutant [Cellulomonas gilvus ATCC 13127]
3AFJ_A 0.0 1 813 21 840
CrystalStructure of Cellvibrio gilvus Cellobiose Phosphorylase triple mutant [Cellulomonas gilvus ATCC 13127],3AFJ_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase triple mutant [Cellulomonas gilvus ATCC 13127]
3QDE_A 0.0 1 816 1 811
ChainA, Cellobiose phosphorylase [Acetivibrio thermocellus],3QDE_B Chain B, Cellobiose phosphorylase [Acetivibrio thermocellus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap40811221632042442853263674084484895305716126526937347751816sp|B9K7M6|CBPA_THENN1816sp|Q76IQ9|CHBP_VIBPR1816sp|Q9F8X1|CHBP_VIBFU3788sp|P20471|NDVB_RHIME69790sp|Q7S0S2|CELAP_NEUCR
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B9K7M6 0.0 1 816 1 813
Cellobiose phosphorylase OS=Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E) OX=309803 GN=cbpA PE=1 SV=1
Q76IQ9 3.63e-165 1 816 1 801
N,N'-diacetylchitobiose phosphorylase OS=Vibrio proteolyticus OX=671 GN=chbP PE=1 SV=1
Q9F8X1 2.22e-152 1 816 1 800
N,N'-diacetylchitobiose phosphorylase OS=Vibrio furnissii OX=29494 GN=chbP PE=1 SV=1
P20471 1.79e-72 3 788 2052 2818
Cyclic beta-(1,2)-glucan synthase NdvB OS=Rhizobium meliloti (strain 1021) OX=266834 GN=ndvB PE=1 SV=2
Q7S0S2 3.43e-46 69 790 84 763
Cellobionic acid phosphorylase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=NCU09425 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000061 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001908_00090.