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CAZyme Information: MGYG000000452_00092

You are here: Home > Sequence: MGYG000000452_00092

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Barnesiella sp002159975
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Barnesiellaceae; Barnesiella; Barnesiella sp002159975
CAZyme ID MGYG000000452_00092
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
727 82367.64 5.7741
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000452 2678398 MAG Sweden Europe
Gene Location Start: 108097;  End: 110280  Strand: +

Full Sequence      Download help

MNSIKHLILA  GAMVCIPILS  NGQQLVSPDG  NLVMNFSLTA  NGAPAYDLSY  KGKPVIKTST60
LGLELKREDP  NAQTDFQLSG  PKKIEGLEAK  ANLMNGFTVA  QTQTSSFDET  WTPVWGEESQ120
IRNHYNELAV  TLDQPQNKRQ  IVIRFRLFND  GLGFRYEFPQ  QKELNYFVIK  EEHSQFAMAG180
DHTAFWIPGD  YDTQEYDYTT  SRLSEIRGLM  KQAITPNSSQ  TPFSPTGVQT  ALMMKTDDGL240
YINLHEAALV  DYSCMHLNLD  DKNLVFESWL  TPDAKGDKGY  MQTPCRSPWR  TIIVSDDARD300
ILASRITLNL  NEPCKLTDTS  WIKPTKYIGI  WWDMITGKGT  WAYTNDLYSV  HLDETDYSKT360
KPNGTHSANT  ENVKRYIDFA  AANGFDAVLV  EGWNIGWEDW  FGNSKDYVFD  FVTPYPDFDV420
QEIHRYAAEK  GVEMIMHHET  SSSVRNYERH  MDNAYRFMVD  NGYHAVKSGY  VGDIIPRGEH480
HYGQWMVNHY  LYAVDKAADY  KIMVNAHEAV  RPTGLCRTYP  NLIANESARG  TEYEAFGGNH540
VNHTTILPFT  RLIGGPMDYT  PGIFETDCSK  MTPSNTSRAR  TTLARQLALY  VTMYSPLQMA600
ADIPENYQRF  PDAFQFIKDV  AIDWDESKYL  EAEPGEYITI  ARRAKGTDDW  YIGCTAGYNG660
HKSELVLDFL  TPGKKYEATI  YADAKDAHWE  PNPQAYTITH  KKVTNKSKLK  LTAAVGGGYA720
ISIKEIK727

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap367210914518121825429032736339943647250854558161765469014723GH97
Family Start End Evalue family coverage
GH97 14 723 1e-258 0.9904912836767037

CDD Domains      download full data without filtering help

Created with Snap3672109145181218254290327363399436472508545581617654690318621Glyco_hydro_9727313GH97_N624724GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 4.19e-148 318 621 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 1.03e-102 27 313 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 1.07e-46 624 724 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap367210914518121825429032736339943647250854558161765469020727ADY34774.1|GH974727QRO24575.1|GH975727QRM98896.1|GH975727CBK69612.1|GH975727QIU94095.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
ADY34774.1 0.0 20 727 19 726
QRO24575.1 0.0 4 727 3 726
QRM98896.1 0.0 5 727 3 725
CBK69612.1 0.0 5 727 3 725
QIU94095.1 0.0 5 727 3 725

PDB Hits      download full data without filtering help

Created with Snap3672109145181218254290327363399436472508545581617654690237272D73_A247272JKA_A237273WFA_A277265HQ4_A277265HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 23 727 23 727
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 24 727 13 716
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 23 727 3 707
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 8.23e-174 27 726 5 661
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 8.23e-174 27 726 5 661
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap367210914518121825429032736339943647250854558161765469012727sp|G8JZS4|SUSB_BACTN25724sp|Q8A6L0|AGAL_BACTN146667sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 12 727 11 727
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 2.02e-70 25 724 25 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 4.80e-29 146 667 137 574
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.002979 0.919078 0.076884 0.000329 0.000363 0.000356

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000452_00092.