You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000964_00054
You are here: Home > Sequence: MGYG000000964_00054
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phocaeicola salanitronis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola salanitronis | |||||||||||
| CAZyme ID | MGYG000000964_00054 | |||||||||||
| CAZy Family | GH97 | |||||||||||
| CAZyme Description | Retaining alpha-galactosidase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 60164; End: 62101 Strand: - | |||||||||||
Full Sequence Download help
| MKHFVAGIMM CVAGVSMYAA APEKLEVKSP DGTQQVEFYV SRSASGANVL CYQVYYKGEK | 60 |
| VIGPSRAGLE LDNRVWEMAL GKRSLPQPDC WMDTMEADSV SYGSCDETWH PLYGERGTVR | 120 |
| DRHNSGTLYL SRKDGSGYRM NIEVRAYDEG IAFRYFFPEH PQAIFHKVVG DLTEYTLPEG | 180 |
| TKAWAEQWAQ APFEHVDVNA LKQPVERALT LELPGGTWMA LADADVDDWC LTKFLASQEK | 240 |
| PNTLTSVMYS PVDAVTYFAS PWKVIMVADK PGELLEHNDI IQNLNPPCEI ADVSWIKPGK | 300 |
| IMRETTLTTA GAMETIDFCA AHKIPYMLFD WQWYMPCTSF DGDATQVVSK LDLPKVIAYG | 360 |
| KKKGVGVWLY VNQHALQKQM RELFPLLRKW GVVGVKSGFV QYASHRWAVW LHDMVRYAAE | 420 |
| NRLMINIHDE FRPSGFSRTY PNLLTQEGIH GNEEFPDATH NTILPFTRMI NGAADYTICY | 480 |
| YDKRLKTTHA HQLAASLVFY SPLQTLFWYD KPSFYGGEPE ITWFEQLQTV FDDTKVLGGE | 540 |
| PGKYVSIARR SGKTWFVGLL GNNEASSRQI DLSFLDEGQT YIAYVYADGG EETGTRTQVK | 600 |
| CSEWLVDGKQ ALRFALKPRG GAAVRLVPVS DQDDRKVESY QGQLL | 645 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH97 | 17 | 626 | 1.3e-170 | 0.9857369255150554 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam10566 | Glyco_hydro_97 | 5.42e-64 | 292 | 524 | 1 | 273 | Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands. |
| pfam14508 | GH97_N | 2.17e-63 | 29 | 287 | 1 | 235 | Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole. |
| pfam14509 | GH97_C | 9.82e-33 | 531 | 627 | 1 | 97 | Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADY35564.1 | 0.0 | 1 | 645 | 1 | 645 |
| AII66307.1 | 0.0 | 4 | 645 | 6 | 645 |
| QJR54190.1 | 0.0 | 4 | 645 | 6 | 645 |
| ALA72156.1 | 0.0 | 4 | 645 | 6 | 645 |
| QJR61012.1 | 0.0 | 4 | 645 | 6 | 645 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5E1Q_A | 5.94e-58 | 29 | 626 | 20 | 654 | Mutant(D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482],5E1Q_B Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482] |
| 3A24_A | 4.48e-57 | 29 | 626 | 6 | 640 | Crystalstructure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron],3A24_B Crystal structure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron] |
| 5HQC_A | 1.23e-55 | 27 | 625 | 3 | 657 | AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQ4_A | 1.68e-55 | 27 | 625 | 3 | 657 | AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQB_A | 4.38e-55 | 27 | 625 | 3 | 657 | AGlycoside Hydrolase Family 97 enzyme (E480Q) in complex with Panose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q8A6L0 | 3.63e-57 | 8 | 626 | 7 | 661 | Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1 |
| G8JZS4 | 1.00e-52 | 15 | 636 | 15 | 733 | Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1 |
| D7CFN7 | 9.58e-47 | 8 | 558 | 13 | 560 | Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000271 | 0.999095 | 0.000171 | 0.000159 | 0.000148 | 0.000134 |