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CAZyme Information: MGYG000001633_00009

You are here: Home > Sequence: MGYG000001633_00009

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species RC9 sp000435075
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; UBA932; RC9; RC9 sp000435075
CAZyme ID MGYG000001633_00009
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
708 MGYG000001633_1|CGC1 80894.09 5.5183
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001633 2721018 MAG China Asia
Gene Location Start: 16224;  End: 18350  Strand: -

Full Sequence      Download help

MKRFLLFFVF  IASGIFTLSA  NEVENAFSPD  GKIRLSFSLS  EEGRPQYSLD  YGELPAVLTS60
GMGFEMMGKS  DDLKSHLDRE  FEMTGTSRAE  SDETWSPVWG  EETSIRNHYN  ELVVNLKQRQ120
TGRKMNIRFR  VYDDGVGFRY  EFPQQESLVY  FVVKEEHTQF  AMPGDITAWW  IPGDYYTQEY180
DYTCCRLSQI  RDVNSKRMNT  NMFSPTGVQT  SLQLKTDQGL  YVNIHEAALV  DYACMHLNLD240
DSNFVFESFL  NPDATGAKGY  LQAPLNTPWR  TVIVSDDARD  ILASRMTLNL  NEPCKIEDTS300
WIRPIKYVGV  WWEMITGKSQ  WSYTWDLPSV  QLGVTDYTKV  RPHGHHGATT  ENVKKYIDFA360
SENGFDAVLV  EGWNEGWEDW  FGHLKDYVFD  FVTPYPDFNL  EEIRDYAKSK  GVEMIMHHET420
SASVRNYERH  LDTAYTFMKN  NGYNAVKSGY  VGNMLPRGEQ  HYSQWMVNHY  LYAVTEAAKY480
KIMVNAHEAV  RPTGLCRTWP  NLIGNESARG  TEYQAFGGSK  PGHVCILPFT  RLLGGPMDYT540
PGIFEMNISK  FSPGNKSHVN  ATIANQLALY  VTMYSPLQMA  ADLPENYERF  PDAFQFIKNV600
AMEWSESKYL  EAEPFEYVTT  ARRVKDSGDW  FVGSTAGADG  HISKIAFSFL  EPGKKYEATL660
YADAPDADYK  TNPQAYVIRK  MKIDHKSKLV  QKCAAGGGYA  IEIREIKN708

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap357010614117721224728331835438942446049553156660163767219703GH97
Family Start End Evalue family coverage
GH97 19 703 1.7e-242 0.9841521394611727

CDD Domains      download full data without filtering help

Created with Snap3570106141177212247283318354389424460495531566601637672298601Glyco_hydro_9728293GH97_N604704GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 1.61e-145 298 601 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 3.23e-98 28 293 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 1.83e-40 604 704 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap357010614117721224728331835438942446049553156660163767228704AMP99644.1|GH9724706AHF13486.1|GH976707QSB26993.1|GH971707AOZ99332.1|GH971705QEE48456.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
AMP99644.1 0.0 28 704 24 700
AHF13486.1 0.0 24 706 22 719
QSB26993.1 0.0 6 707 4 704
AOZ99332.1 0.0 1 707 1 704
QEE48456.1 0.0 1 705 1 702

PDB Hits      download full data without filtering help

Created with Snap3570106141177212247283318354389424460495531566601637672127082D73_A287082JKA_A287083WFA_A287065HQ4_A287065HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 12 708 11 728
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 28 708 16 717
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 28 708 7 708
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 2.00e-157 28 706 5 661
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 2.00e-157 28 706 5 661
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap357010614117721224728331835438942446049553156660163767220708sp|G8JZS4|SUSB_BACTN17704sp|Q8A6L0|AGAL_BACTN122645sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 20 708 19 728
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 2.74e-61 17 704 16 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 2.42e-32 122 645 129 572
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000377 0.998806 0.000267 0.000179 0.000178 0.000165

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001633_00009.