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CAZyme Information: MGYG000002157_00175

You are here: Home > Sequence: MGYG000002157_00175

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Amulumruptor sp001689515
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; Amulumruptor; Amulumruptor sp001689515
CAZyme ID MGYG000002157_00175
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
725 MGYG000002157_2|CGC3 81573.46 5.6594
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002157 2499032 MAG Germany Europe
Gene Location Start: 91535;  End: 93712  Strand: +

Full Sequence      Download help

MEGKMKNLLM  LAAVGVPLAL  GAEQVTSPDG  ALVVDVDIAA  GGIPTYKVDY  KGKPVVLPSR60
LGFTLASESS  RRDFSADAVK  TSADALQMTS  GFAITDIERG  AVDETWAPVW  GEEDSIRCNY120
NEMALKLTQT  DLDRYMIVRF  RVFNDGLGFR  YEFPAQPHMT  YFVIKEENTQ  FAMTGDHWAY180
WIPGDYDTQE  YNYTKSRMSH  IRDSWEQHKK  ESSANASSTL  FSPTGVQTAL  QLKTDDGIYL240
NIHEAGVKDY  PTMHLNLDEA  TNTFTSHLTP  DATGMKGYMQ  TPEETPWRTI  MVVDDARDIL300
ASRLILNLNE  PTAYEDTSWI  KPVKYMGVWW  EMIAGKGDWS  YTNDLASIKL  GETDYTKTKP360
HGHHSANTEN  VKRYIDFAAE  HGFDQVLVEG  WNEGWEDWIG  NSKDYVFDFV  TPYPDFDLEG420
LNKYAKEKGV  KLMMHHETSG  STRNYERHLP  AAYKLMNDLG  YNSVKSGYVG  NIIPRGETHY480
SQWSNNHYLY  AITEAAKHHI  MVNAHEASRP  TGLSRTYPNL  IGNESARGTE  YQAMGGNAKW540
HTSILPFTRL  QGGPMDYTPG  IFEFDLSTFS  RHNNSKIAST  IPGQLALYVT  MYSPLQMAAD600
LPEHYARHMD  AFQFIKDVPV  EWEKSVYLEA  EPMDYVTVAR  KDKNSDEWYV  GSTAGTADRD660
SKITLSFLDP  GRKYTATIYA  EAPDANTVDG  QTRYKITTKT  VTNKSTLKLH  ALAGGGYAIS720
IKPVK725

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap367210814518121725329032636239843547150754358061665268820721GH97
Family Start End Evalue family coverage
GH97 20 721 1.9e-236 0.9809825673534073

CDD Domains      download full data without filtering help

Created with Snap3672108145181217253290326362398435471507543580616652688316619Glyco_hydro_9727311GH97_N622722GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 1.47e-137 316 619 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 7.77e-89 27 311 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 3.29e-38 622 722 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap367210814518121725329032636239843547150754358061665268821724QCD41705.1|GH9723725QCP72455.1|GH9723725QCD38766.1|GH975721ADY35295.1|GH971721QNT67170.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
QCD41705.1 0.0 21 724 21 721
QCP72455.1 0.0 23 725 23 722
QCD38766.1 0.0 23 725 23 722
ADY35295.1 0.0 5 721 1 698
QNT67170.1 0.0 1 721 16 716

PDB Hits      download full data without filtering help

Created with Snap3672108145181217253290326362398435471507543580616652688237252D73_A247252JKA_A237253WFA_A257225HQ4_A257225HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 23 725 23 727
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 24 725 13 716
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 23 725 3 707
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 1.36e-143 25 722 3 659
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 1.36e-143 25 722 3 659
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36721081451812172532903263623984354715075435806166526884725sp|G8JZS4|SUSB_BACTN5722sp|Q8A6L0|AGAL_BACTN21718sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 4 725 3 727
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 3.93e-54 5 722 1 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 1.14e-30 21 718 39 617
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000236 0.999080 0.000191 0.000159 0.000162 0.000143

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002157_00175.