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CAZyme Information: MGYG000001088_00211
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Haemophilus_D parainfluenzae_L | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Pasteurellaceae; Haemophilus_D; Haemophilus_D parainfluenzae_L | |||||||||||
| CAZyme ID | MGYG000001088_00211 | |||||||||||
| CAZy Family | GT19 | |||||||||||
| CAZyme Description | Lipid-A-disaccharide synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 84284; End: 85453 Strand: + | |||||||||||
Full Sequence Download help
| MIKENPTIAI IAGEVSGDIL GAGLIQALKR HYPQAKFVGI GGERMIVQGF ESFFDMEELS | 60 |
| VMGLVEVLKH LPRLLKIRRS IIDQLSDIKP DVFIGIDAPD FNLTVELKLK EKGIKTIHYV | 120 |
| SPSVWAWRQN RIYKIAKATH QVLAFLPFEK AFYDRFNVPC RFIGHTMADA IPLKPNRTEA | 180 |
| CQTLGIDEKG RYLAILVGSR GSEVGFLTEP FLKTALLLKE KYPDLQFLVP LVNEKRRQQF | 240 |
| EEIKAQIAPD LDMHLIDGKA RQVMIAAEAT LLASGTAALE AMLCKSPMVV GYRMKPFTYF | 300 |
| LAKRLVKTKY ISLPNLLADE MLVPEMIQED CEPQKLAEQL SQYLGDDESA VKSRSVLIQR | 360 |
| FTELHKLIQC DADSQAAQAV IDLLEQKHD | 389 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT19 | 8 | 369 | 3.9e-139 | 0.9943502824858758 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR00215 | lpxB | 0.0 | 1 | 383 | 1 | 385 | lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| COG0763 | LpxB | 0.0 | 6 | 386 | 2 | 381 | Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis]. |
| PRK00025 | lpxB | 0.0 | 5 | 387 | 1 | 378 | lipid-A-disaccharide synthase; Reviewed |
| pfam02684 | LpxB | 1.14e-178 | 8 | 380 | 1 | 374 | Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. |
| PRK01021 | lpxB | 4.29e-46 | 5 | 340 | 226 | 566 | lipid-A-disaccharide synthase; Reviewed |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QOR16198.1 | 1.90e-277 | 1 | 389 | 1 | 389 |
| QOR25549.1 | 2.58e-275 | 1 | 389 | 1 | 389 |
| VEI30784.1 | 7.40e-275 | 1 | 389 | 1 | 389 |
| QOR20127.1 | 1.05e-274 | 1 | 389 | 1 | 389 |
| QOR10737.1 | 1.49e-274 | 1 | 389 | 1 | 389 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5W8N_A | 9.03e-164 | 1 | 385 | 1 | 382 | LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)] |
| 5W8S_A | 1.82e-163 | 1 | 385 | 1 | 382 | LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P45011 | 2.37e-224 | 1 | 387 | 1 | 387 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=lpxB PE=3 SV=2 |
| A5UD44 | 3.36e-224 | 1 | 385 | 1 | 385 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain PittEE) OX=374930 GN=lpxB PE=3 SV=1 |
| Q4QLM6 | 3.91e-223 | 1 | 385 | 1 | 385 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain 86-028NP) OX=281310 GN=lpxB PE=3 SV=1 |
| A5UII8 | 1.12e-222 | 1 | 387 | 1 | 387 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain PittGG) OX=374931 GN=lpxB PE=3 SV=1 |
| Q65VI1 | 2.93e-215 | 1 | 387 | 8 | 394 | Lipid-A-disaccharide synthase OS=Mannheimia succiniciproducens (strain MBEL55E) OX=221988 GN=lpxB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000054 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |