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CAZyme Information: MGYG000003836_00796
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-521 sp900545335 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Burkholderiaceae; CAG-521; CAG-521 sp900545335 | |||||||||||
| CAZyme ID | MGYG000003836_00796 | |||||||||||
| CAZy Family | GT19 | |||||||||||
| CAZyme Description | Lipid-A-disaccharide synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 30260; End: 31396 Strand: + | |||||||||||
Full Sequence Download help
| MARDIVWLAG ETSGDFIASL VLPQVAEAYP DESMLGIGGD RMIAAGLKPW HHASALSVRG | 60 |
| YVEVLKKLPS LLMLRREMKR RVSRLSPRAF IGVDAPDFNL SIEESLRQEG IKTIHFVCPS | 120 |
| IWAWRPERIH QIKRAVDHML LIFPFEKKLM DEAGIDSTYI GHPLAREIPM KPNKDAAREK | 180 |
| LKIDPPGPVF AVLPGSRQAE VAWCGPHFFG ACEKVLEFDA RATFLVPAAD AAREAQIKTL | 240 |
| LQNYPKAQKA TRIISSDSHT VMQASDAILV ASGTATLEAA LFKRPMVVGY SMPGLTGILM | 300 |
| QKKGIIDFVS LPNILAGRRL VPEILQYYCR SETLAYALWH EYQRRNDSEL IESFTQMHES | 360 |
| LLRDTPKLAA EAIQKVCG | 378 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT19 | 5 | 361 | 1.2e-115 | 0.9915254237288136 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK00025 | lpxB | 7.46e-151 | 9 | 378 | 8 | 376 | lipid-A-disaccharide synthase; Reviewed |
| COG0763 | LpxB | 4.11e-127 | 9 | 373 | 8 | 375 | Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis]. |
| pfam02684 | LpxB | 3.79e-105 | 5 | 373 | 1 | 374 | Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. |
| TIGR00215 | lpxB | 9.80e-94 | 5 | 376 | 8 | 382 | lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK01021 | lpxB | 4.75e-49 | 9 | 325 | 233 | 551 | lipid-A-disaccharide synthase; Reviewed |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ANU65980.1 | 2.95e-156 | 2 | 376 | 6 | 380 |
| QQQ97139.1 | 2.95e-156 | 2 | 376 | 6 | 380 |
| QQS88891.1 | 2.52e-137 | 3 | 374 | 12 | 385 |
| QDA54177.1 | 1.98e-134 | 3 | 375 | 13 | 387 |
| BBF22932.1 | 7.69e-132 | 6 | 378 | 16 | 389 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5W8N_A | 1.44e-75 | 5 | 373 | 9 | 377 | LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)] |
| 5W8S_A | 2.87e-75 | 5 | 373 | 9 | 377 | LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| B2JIB3 | 1.22e-112 | 5 | 373 | 10 | 378 | Lipid-A-disaccharide synthase OS=Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) OX=391038 GN=lpxB PE=3 SV=1 |
| Q39F56 | 3.95e-111 | 5 | 376 | 10 | 381 | Lipid-A-disaccharide synthase OS=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) OX=482957 GN=lpxB PE=3 SV=1 |
| A4JF62 | 3.63e-109 | 5 | 376 | 10 | 381 | Lipid-A-disaccharide synthase OS=Burkholderia vietnamiensis (strain G4 / LMG 22486) OX=269482 GN=lpxB PE=3 SV=1 |
| Q13XC9 | 1.03e-108 | 5 | 376 | 10 | 381 | Lipid-A-disaccharide synthase OS=Paraburkholderia xenovorans (strain LB400) OX=266265 GN=lpxB PE=3 SV=1 |
| B2T5I1 | 2.92e-108 | 5 | 376 | 10 | 381 | Lipid-A-disaccharide synthase OS=Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) OX=398527 GN=lpxB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000041 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |