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CAZyme Information: MGYG000002954_00200
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UBA1191 sp900543485 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Anaerovoracaceae; UBA1191; UBA1191 sp900543485 | |||||||||||
| CAZyme ID | MGYG000002954_00200 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Surfactin synthase subunit 2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 39945; End: 46883 Strand: - | |||||||||||
Full Sequence Download help
| MRREDLEYWN TVLGETYESD GFYTDRPRVT PLRERTQTYI DLGTGGGDFA SDGKWPFAVS | 60 |
| FAAAVSFVMS KNLMKNDVMI GLSAGKESQK GAALTGYVAN LSADMQVAEL KRQIAARREE | 120 |
| ALNHSETFSE ALEHFEMKGN EYVPGLKTII REDGLYPEAQ DTYDADVVFY LCSEKGSVRC | 180 |
| GFAEELYDEG TIDSIASQIR KFMACDGSAR LSEVEVLSDS EIQRIKGMEH GEPHGCISGT | 240 |
| VIDVMREHAV AYASNTAVEE GDVRLTYREF DERTNQVAQK LYSHLGVRGG YVGVYMDNCI | 300 |
| DQAVAIVGIQ KAGCAYIPID EELPAERTRQ IIEDADVSVV FCLEKNMAEL LKLQQACANL | 360 |
| REIICMDSSG YRTEELSKQP VGAVVGPEDT AYAIYTSGTT GKPKGVAVSH GALMELCSSS | 420 |
| DIYDIDETSR SLRYVKVGFD PSVLEVFPFW MRGAAVVNMP GELRTDLDGL SDFMREKRIT | 480 |
| HVTLPTQVCE QMQGYDNEFL KVMITGGDKL KAFRKTSPYR LLNNYGPTEN TVSTTIFEVD | 540 |
| RGYKSIPIGR PFGNTAVYIV DQYGRRQAEG VPGELWIGGG RLAEGYINNR ELTDSVFFSS | 600 |
| DLLEEKRVYR SGDIARWLPD GNLDFAGRID NQVKISAFRI ETEEVEAVMS AIGGVESTVV | 660 |
| SAISGNDGQK ALCAYYTGNP ELSEAWLRDE LKRTLPPFMI PKYFVHLQEI PLTLNGKIDY | 720 |
| RKLPVPGIRA SELLKPENER EEKMWRLWRD VLGTDKFGVT DDFFQAGGNS IQAMRLISEW | 780 |
| NRSGEPAIAF SEMTAEPSVR AMCMKIAERA HNDETPEGDE RRVPALDLKE RYEPFNLSQM | 840 |
| QQAYFVGRRG EMHLGQVPTH SYIEFTCEDY DSSRFLCAVK KLMERHDMLH ARFLEDGRQF | 900 |
| VMEHYDVRID EEDLSSLPQE EQQRRVEEIR REMSGMARDC FRESLVTVRV SLLGGERALI | 960 |
| HFYSDGLIID GWSLELLMRD MEYFYEDIAR DMPDTPLLFR NYVEFMESRR HTAEYRKSEA | 1020 |
| FWLKKIPELP EAPALPMKQT GKGAETIEVC KHTGTLSKDE WNRFEAACRK FGFTSFTGLL | 1080 |
| TAFGEVVGAW SKKKDFCINV PTFNRMAAGG MADNTVGECA SFFLFAMEHS RSSFIEKAER | 1140 |
| NRRELALLME HDSYTGIDVQ RKISQMKGSV GDYSIPVVFT SLLDIPAVEQ KHFKKTFVMT | 1200 |
| HTSQVWIDAV AQYCNDRIEF SWDCVDNLFE DGVAENMVRA FVSRLKQLGE REEAWHEAAG | 1260 |
| LDVPEAREAA ERINNVRMDL GNMTLGQLLA EGRRKFGSRI AAVQGNDALT YDMFYDLVRG | 1320 |
| HAAEMKRAGV KPGDVVAIAI EKSFDQLAAT VAAVMTGAVY LPLDVHLNEE RIRYCIEEAG | 1380 |
| SKAAVFDSDT KHLMKNISEN VRSYNADEVT PPDGGCELHV ESRTMDDLFC IIYTSGSTGR | 1440 |
| PKGVMIQQRG LINALLYTNR YYDVTEDDKV LTVTNLSHDM SMYDLFGMLI AGGCIVLPDK | 1500 |
| RDVKNPKHWI ELINRHGVSI WNSAPALMEM MLEIMSLENI SGLQTVRLAI MGGDVMRKTV | 1560 |
| PASLWKHNPD MKVVNVGGPT ETTLWNIHHE VTREDLERNR IPYGLPMANT KYYILNEILE | 1620 |
| ICPVYTEGIM YVEGVGVTRG YLNDEEQTAA KYITNPYTGN RMYCTGDVGR YLESGEIDII | 1680 |
| GRDDLQIKIN GKRIELEEIE QVVYENKDIA FAAAVLLREE NAISLYCRCI SDIREEDVRK | 1740 |
| ELEKKLPDYM LPKYITFIES VPLSRNGKVD RKALAQIRIS NAAAEVTRDD EYVTDGERKL | 1800 |
| IALYNRVIGT QRTMPESNFF SLGGDSLKAI KLLYEVNSEF NTALTLTDIF NNPSVRGLAS | 1860 |
| YIQTISEEDM DKLTIRKCQD TGGIPLGLAQ EGIWFVNRSV EDQDCGQRYN LVGSMEIGAS | 1920 |
| LDVENFAEAI NKTVDCCRGL RAEIYEDDYR PYQRTVDELT IDLTCEDRSG ESAEDVRRSF | 1980 |
| EDEEMRRRYV LEKAPLFNFR LGRAEEGIYV FTMGIHHILV DAYSVNLILR KIKEIYFDLE | 2040 |
| EGRNREYAED VSFQDFASWQ TDAYRDGLFD GDIDYWKEKL AGELTRIELS ETELSTWDHF | 2100 |
| EGGVCDLPLD ADELSRLKEL CSNMEMTVFA GLTTIYYMFL AWLCGADDIC LGSASSGRVR | 2160 |
| SEIRSTVGNF ANVLLLRTTV RPDDSFSSLA RRVKETMDGA YAHQSLPFEK VAERACLSYE | 2220 |
| YRDLPYKLLI DYIDLEDDSR RGIFGDFEYT RQLSAADLDL FIQSVNDEFQ FQFYYKKRLF | 2280 |
| AEDEIEEFAG LIQDILSAAV EAPDKPWNDY DL | 2312 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK12467 | PRK12467 | 0.0 | 2 | 2104 | 236 | 2388 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 0.0 | 174 | 2301 | 1934 | 4064 | peptide synthase; Provisional |
| PRK05691 | PRK05691 | 4.10e-157 | 6 | 2115 | 866 | 3006 | peptide synthase; Validated |
| cd05930 | A_NRPS | 7.67e-148 | 255 | 723 | 3 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
| PRK12467 | PRK12467 | 7.11e-144 | 882 | 2312 | 96 | 1550 | peptide synthase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QND46664.1 | 1.14e-169 | 262 | 1882 | 1032 | 2682 |
| ACX49739.1 | 1.97e-95 | 185 | 1528 | 403 | 1818 |
| BAY90071.1 | 9.05e-84 | 6 | 779 | 2426 | 3256 |
| BAY30132.1 | 1.19e-83 | 6 | 808 | 2437 | 3296 |
| BAZ00088.1 | 7.77e-81 | 6 | 779 | 2435 | 3265 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6MFZ_A | 2.61e-191 | 255 | 1862 | 221 | 1797 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
| 6MFY_A | 1.04e-182 | 255 | 1785 | 221 | 1723 | Crystalstructure of a 5-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis],6MG0_A Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis],6MG0_B Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis] |
| 7LY7_A | 7.12e-143 | 833 | 1866 | 9 | 1020 | ChainA, BmdB, Bacillamide NRPS [Thermoactinomyces vulgaris] |
| 7LY4_E | 7.30e-143 | 833 | 1866 | 9 | 1020 | ChainE, BmdB, bacillamide NRPS [Thermoactinomyces vulgaris] |
| 6LTA_A | 2.13e-128 | 816 | 1862 | 36 | 1098 | ChainA, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTB_A Chain A, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTC_A Chain A, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTD_A Chain A, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTD_B Chain B, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O68006 | 1.28e-268 | 240 | 2312 | 38 | 2101 | Bacitracin synthase 1 OS=Bacillus licheniformis OX=1402 GN=bacA PE=3 SV=1 |
| Q04747 | 2.59e-235 | 160 | 2306 | 383 | 2511 | Surfactin synthase subunit 2 OS=Bacillus subtilis (strain 168) OX=224308 GN=srfAB PE=1 SV=3 |
| P0C064 | 4.19e-234 | 182 | 2312 | 1445 | 3564 | Gramicidin S synthase 2 OS=Brevibacillus brevis OX=1393 GN=grsB PE=1 SV=2 |
| P0C063 | 1.03e-228 | 182 | 2312 | 1445 | 3565 | Gramicidin S synthase 2 OS=Aneurinibacillus migulanus OX=47500 GN=grsB PE=3 SV=2 |
| O30409 | 1.67e-224 | 182 | 2300 | 1439 | 3539 | Tyrocidine synthase 3 OS=Brevibacillus parabrevis OX=54914 GN=tycC PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999832 | 0.000168 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |