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CAZyme Information: MGYG000000001_01204

You are here: Home > Sequence: MGYG000000001_01204

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species GCA-900066495 sp902362365
Lineage Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; GCA-900066495; GCA-900066495 sp902362365
CAZyme ID MGYG000000001_01204
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
411 MGYG000000001_13|CGC1 45630.63 8.9244
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000001 3219617 Isolate United Kingdom Europe
Gene Location Start: 44459;  End: 45694  Strand: +

Full Sequence      Download help

MRVLLSGGGT  GGHVYPAIAI  ANRIKEQYPD  AEIIFVGTEK  GIESEIVPKY  GYELKTVTVQ60
GFKRKIDFDN  VKRVFKLFKG  LEQSRKVVKK  FKPDVVIGTG  GYVSGPVLFN  AAMSKVPTVI120
HEQNSFPGVT  NKILSKVVTR  VLTSFEDSHE  RFPEGSRDKL  VLTGNPVRKE  ILVARKNIAR180
KNLGISEDKK  MVLCYGGSGG  SEEINDAMKV  VIENMVKEDI  AFIFATGKYY  YEEFTKSIEY240
LNLKPYQQVV  PYLEDMANAL  AASDLVIGSA  GAISLAEITA  LGKPSIIIPK  AYTAENHQEY300
NAKSIESKGA  GIAILEKDLT  PKTLNETVFR  LLGDRELLID  MENASKKIGK  PEAIDLICDE360
IIKIYEEKNK  VKKSNIEDKN  TDIKEKDEKE  SSLDNNNDSK  EQPKVIGIKK  K411

Enzyme Prediction      help

No EC number prediction in MGYG000000001_01204.

CAZyme Signature Domains help

Created with Snap20416182102123143164184205226246267287308328349369390192353GT28
Family Start End Evalue family coverage
GT28 192 353 1.8e-44 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap204161821021231431641842052262462672873083283493693901364murG2360GT28_MurG1364MurG1361murG2361PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 1.91e-153 1 364 2 354
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 9.15e-151 2 360 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 4.19e-115 1 364 1 354
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 3.22e-110 1 361 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 3.32e-53 2 361 3 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap204161821021231431641842052262462672873083283493693901411QJA09280.1|GT281411CEI73801.1|GT281411CED94604.1|GT281365QQY77001.1|GT281365QQY72156.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QJA09280.1 2.43e-246 1 411 1 414
CEI73801.1 4.38e-237 1 411 1 412
CED94604.1 2.58e-231 1 411 1 411
QQY77001.1 8.10e-225 1 365 1 365
QQY72156.1 8.10e-225 1 365 1 365

PDB Hits      download full data without filtering help

Created with Snap2041618210212314316418420522624626728730832834936939023643S2U_A23641F0K_A23647D1I_A1153486KQW_A1153486KQX_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 5.09e-55 2 364 4 354
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.25e-50 2 364 8 353
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 5.44e-48 2 364 11 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
6KQW_A 2.08e-06 115 348 162 368
ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168]
6KQX_A 2.11e-06 115 348 162 368
ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168],7BOV_A Chain A, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168]

Swiss-Prot Hits      download full data without filtering help

Created with Snap204161821021231431641842052262462672873083283493693901365sp|Q182Y6|MURG_CLOD61363sp|A3DE27|MURG_ACET21368sp|A8MH36|MURG_ALKOO1362sp|A6TS61|MURG_ALKMQ1357sp|B0K8K7|MURG_THEP3
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q182Y6 4.81e-225 1 365 2 366
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridioides difficile (strain 630) OX=272563 GN=murG PE=3 SV=1
A3DE27 5.15e-118 1 363 1 360
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
A8MH36 7.94e-114 1 368 1 366
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus oremlandii (strain OhILAs) OX=350688 GN=murG PE=3 SV=1
A6TS61 1.03e-111 1 362 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus metalliredigens (strain QYMF) OX=293826 GN=murG PE=3 SV=1
B0K8K7 4.43e-110 1 357 1 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000069 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000001_01204.