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CAZyme Information: MGYG000000010_02565

You are here: Home > Sequence: MGYG000000010_02565

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Staphylococcus_A lentus
Lineage Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus_A; Staphylococcus_A lentus
CAZyme ID MGYG000000010_02565
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
355 MGYG000000010_34|CGC1 39902.02 9.0913
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000010 2726400 Isolate United Kingdom Europe
Gene Location Start: 13189;  End: 14256  Strand: -

Full Sequence      Download help

MKKIAFTGGG  TIGHVAVNLA  LIPEAEQRGI  ETVYIGSKNG  IEKDMITDSA  KTTKYIPISS60
GKLRRYLSFE  NLKDVFKVLK  GVLDARKALK  KEKPDLVFSK  GGFVSVPVII  AAKSLKIPTI120
IHESDVTPGL  ANKISMKFAN  KMYTTFEETL  KYVPKEKSDF  IGAIIREDLR  DGKKEEGYKI180
TGFNDKLPVL  LVMGGSLGSK  ILNEAVRDNL  DYLTKKYQII  HLTGKGHKDE  SIENDHYVQY240
EFVSSELMHF  YAISDTVISR  AGANAIYEFA  TLKIPMLLIP  LGLDQSRGDQ  IDNAKIFEKN300
GYAKVIQEKE  VNQNTLVRNL  DQLENERETL  IENMSKFKES  YTKESLFNKI  ESDIQ355

Enzyme Prediction      help

No EC number prediction in MGYG000000010_02565.

CAZyme Signature Domains help

Created with Snap1735537188106124142159177195213230248266284301319337190339GT28
Family Start End Evalue family coverage
GT28 190 339 1.9e-38 0.9490445859872612

CDD Domains      download full data without filtering help

Created with Snap17355371881061241421591771952132302482662843013193371336murG1338PRK124463336GT28_MurG2354MurG2344murG
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 1.33e-136 1 336 1 333
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
PRK12446 PRK12446 1.12e-127 1 338 1 337
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed
cd03785 GT28_MurG 1.24e-109 3 336 1 333
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 7.10e-107 2 354 1 355
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.13e-92 2 344 1 338
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits      help

Created with Snap17355371881061241421591771952132302482662843013193371355QMU11032.1|GT281355QPW11360.1|GT281355QQQ09117.1|GT281355QDR64141.1|GT281355QSN66379.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QMU11032.1 3.35e-247 1 355 1 355
QPW11360.1 1.20e-224 1 355 1 355
QQQ09117.1 1.20e-224 1 355 1 355
QDR64141.1 1.20e-224 1 355 1 355
QSN66379.1 1.20e-224 1 355 1 355

PDB Hits      download full data without filtering help

Created with Snap173553718810612414215917719521323024826628430131933723201F0K_A23087D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 4.50e-26 2 320 7 319
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 1.39e-23 2 308 10 318
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap17355371881061241421591771952132302482662843013193371353sp|Q2YY01|MURG_STAAB1353sp|P65481|MURG_STAAM1353sp|P65482|MURG_STAAN1353sp|Q2FYL5|MURG_STAA81353sp|Q6G9E3|MURG_STAAS
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q2YY01 6.05e-168 1 353 1 353
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) OX=273036 GN=murG PE=3 SV=1
P65481 6.05e-168 1 353 1 353
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) OX=158878 GN=murG PE=3 SV=1
P65482 6.05e-168 1 353 1 353
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus aureus (strain N315) OX=158879 GN=murG PE=1 SV=1
Q2FYL5 6.05e-168 1 353 1 353
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=murG PE=3 SV=1
Q6G9E3 6.05e-168 1 353 1 353
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus aureus (strain MSSA476) OX=282459 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000070 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000010_02565.