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CAZyme Information: MGYG000000122_00035

You are here: Home > Sequence: MGYG000000122_00035

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Staphylococcus epidermidis
Lineage Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus epidermidis
CAZyme ID MGYG000000122_00035
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
357 MGYG000000122_1|CGC1 40233.31 8.2605
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000122 2560588 Isolate Canada North America
Gene Location Start: 36686;  End: 37759  Strand: -

Full Sequence      Download help

MTKIAYTGGG  TVGHVSVNLS  LIPTSIEKGH  EAFYIGSKHG  IEREMIESQL  PDIQYYPISS60
GKLRRYLSFE  NAKDVFKVLK  GILDARKILK  KQKPDLLFSK  GGFVSVPVVI  AARSLKIPTI120
IHESDLTPGL  ANKISLKFAK  KIYTTFEDTL  TYLPKDKADF  VGATVREDLK  QGNKERGYQL180
TDFDKNKKVL  LVMGGSLGSK  KLNNIIRQNI  EALLHDYQII  HLTGKGLVDD  SINKKGYVQF240
EFVKDDLTDL  LAITDTVVSR  AGSNAIYEFL  TLRIPMLLIP  LGLDQSRGDQ  IDNAKNFESK300
GYGRHIPEDQ  LTEVNLLQEL  NDIELHRESI  IKQMETYQES  YTKEDLFDKI  IHDALNK357

Enzyme Prediction      help

No EC number prediction in MGYG000000122_00035.

CAZyme Signature Domains help

Created with Snap1735537189107124142160178196214232249267285303321339190340GT28
Family Start End Evalue family coverage
GT28 190 340 1.3e-33 0.9490445859872612

CDD Domains      download full data without filtering help

Created with Snap17355371891071241421601781962142322492672853033213391351murG1350PRK124463351MurG3351GT28_MurG3350murG
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 3.46e-135 1 351 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
PRK12446 PRK12446 1.15e-129 1 350 1 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed
COG0707 MurG 1.46e-107 3 351 2 348
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
cd03785 GT28_MurG 8.77e-104 3 351 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
TIGR01133 murG 3.72e-83 3 350 2 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits      help

Created with Snap17355371891071241421601781962142322492672853033213391357QQE97308.1|GT281357ARG66655.1|GT281357QRJ51230.1|GT281357AAT19637.1|GT281357QGY84881.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QQE97308.1 8.04e-256 1 357 1 357
ARG66655.1 8.04e-256 1 357 1 357
QRJ51230.1 8.04e-256 1 357 1 357
AAT19637.1 8.04e-256 1 357 1 357
QGY84881.1 8.04e-256 1 357 1 357

PDB Hits      download full data without filtering help

Created with Snap173553718910712414216017819621423224926728530332133933121F0K_A103127D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 3.65e-23 3 312 8 311
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 2.26e-19 10 312 18 322
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap17355371891071241421601781962142322492672853033213391357sp|Q8CMM3|MURG_STAES1357sp|Q5HPC0|MURG_STAEQ1355sp|Q4L6C8|MURG_STAHJ1357sp|Q49XM9|MURG_STAS11356sp|Q2YY01|MURG_STAAB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8CMM3 6.54e-256 1 357 1 357
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=murG PE=3 SV=1
Q5HPC0 6.54e-256 1 357 1 357
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=murG PE=3 SV=1
Q4L6C8 1.31e-218 1 355 1 355
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus haemolyticus (strain JCSC1435) OX=279808 GN=murG PE=3 SV=1
Q49XM9 3.68e-205 1 357 1 358
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41) OX=342451 GN=murG PE=3 SV=1
Q2YY01 9.80e-205 1 356 1 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) OX=273036 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000040 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000122_00035.