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CAZyme Information: MGYG000000296_00689

You are here: Home > Sequence: MGYG000000296_00689

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Peptostreptococcus anaerobius
Lineage Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Peptostreptococcus; Peptostreptococcus anaerobius
CAZyme ID MGYG000000296_00689
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
367 MGYG000000296_6|CGC2 40276.6 9.3607
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000296 1868390 MAG Sweden Europe
Gene Location Start: 44513;  End: 45616  Strand: -

Full Sequence      Download help

MRVILSGGGT  GGHVYPAIAI  ANKIKENNPD  AEILFVGTKE  GIESEIVPKY  GYDIEYIRVK60
GFKRKIDFEN  VKRVLMFIKS  LSDSKRIIKK  FKPDMVIGTG  GYVSGSVVLR  ASKMGIKTCI120
HEQNSFPGMT  NKMLSKNVDF  VMTSFVDSHK  RFAEGVRGKL  RLTGNPVRDD  ILTTKKEDAR180
KKLGIDTDKR  MVLVSGGSGG  SEEINDALKL  ALPKMVEDKI  AFMVATGRTY  YDKFMADYGH240
LKLGQDQKIV  PYLDDMANNL  VAADLTIGSA  GAISLAEITA  VGIPAIIVPK  AYTAENHQEY300
NAKSLEAAGA  GICITEKELN  PESLDRAIFS  LINDGDRLKK  MSEASKEFGK  PDALEKIYKH360
VEDALNK367

Enzyme Prediction      help

No EC number prediction in MGYG000000296_00689.

CAZyme Signature Domains help

Created with Snap1836557391110128146165183201220238256275293311330348191353GT28
Family Start End Evalue family coverage
GT28 191 353 2.3e-46 0.9936305732484076

CDD Domains      download full data without filtering help

Created with Snap18365573911101281461651832012202382562752933113303481367murG2360GT28_MurG1367MurG1359murG3143Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 9.78e-143 1 367 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.63e-142 2 360 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.48e-113 1 367 1 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.70e-106 1 359 1 346
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 8.64e-42 3 143 1 139
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18365573911101281461651832012202382562752933113303481367AUN15465.1|GT281365QEK20347.1|GT281367CEJ74863.1|GT281367CEK39311.1|GT281365QQQ86033.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
AUN15465.1 2.17e-162 1 367 1 367
QEK20347.1 4.99e-162 1 365 1 365
CEJ74863.1 6.18e-162 1 367 1 367
CEK39311.1 1.24e-161 1 367 1 367
QQQ86033.1 1.43e-161 1 365 1 365

PDB Hits      download full data without filtering help

Created with Snap183655739111012814616518320122023825627529331133034823573S2U_A23611F0K_A23677D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 8.62e-50 2 357 4 347
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 2.47e-48 2 361 8 350
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 8.54e-44 2 367 11 364
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573911101281461651832012202382562752933113303481366sp|Q182Y6|MURG_CLOD61367sp|A8MH36|MURG_ALKOO1361sp|A6TS61|MURG_ALKMQ1365sp|A3DE27|MURG_ACET21361sp|Q8R9G6|MURG_CALS4
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q182Y6 4.90e-159 1 366 2 367
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridioides difficile (strain 630) OX=272563 GN=murG PE=3 SV=1
A8MH36 2.55e-111 1 367 1 365
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus oremlandii (strain OhILAs) OX=350688 GN=murG PE=3 SV=1
A6TS61 2.17e-107 1 361 1 360
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus metalliredigens (strain QYMF) OX=293826 GN=murG PE=3 SV=1
A3DE27 4.79e-107 1 365 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
Q8R9G6 5.09e-100 1 361 1 360
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000046 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000296_00689.