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CAZyme Information: MGYG000000767_00682

You are here: Home > Sequence: MGYG000000767_00682

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Paraeggerthella hongkongensis
Lineage Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Eggerthellaceae; Paraeggerthella; Paraeggerthella hongkongensis
CAZyme ID MGYG000000767_00682
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
372 MGYG000000767_33|CGC1 39388.93 5.8925
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000767 2269129 MAG Japan Asia
Gene Location Start: 8326;  End: 9444  Strand: +

Full Sequence      Download help

MLIVLSGGGT  AGHINPALAL  AEELEKRGCT  VRFAGTPTGV  ESRLVPAAGI  EFKAFEAQGF60
DRSHPLTLPK  AIMKIQKSTG  EAKRWFDEIQ  PDAVVGFGGY  VCIPVARAAE  QCDIPVVVHE120
QNSVMGMANK  YLAKRAAAVC  LTYERAAEAL  SDKSRVEVTG  NPVRSSVFGA  TRAEGRAAFG180
VPDDARMLLV  TGGSLGARHL  NQAVTALKDA  LLSYEDLHVV  HVTGPKELDA  VADALSLGEV240
EARRWHLYGY  TDQMGLAMAA  ADAIVSRAGA  TSLAEISARA  LPALLVPFPY  ATEDHQTMNA300
RACVDAGAAF  MVADADVEGP  EFERLLRTLV  EDADVRERMA  CAARAQKTRD  AAALLADAVM360
QAASSRGSKD  AR372

Enzyme Prediction      help

No EC number prediction in MGYG000000767_00682.

CAZyme Signature Domains help

Created with Snap1837557493111130148167186204223241260279297316334353187351GT28
Family Start End Evalue family coverage
GT28 187 351 3.8e-49 0.9936305732484076

CDD Domains      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343531345murG3345GT28_MurG1349MurG1344murG3317PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 3.21e-129 1 345 2 337
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 4.59e-123 3 345 2 337
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.21e-101 1 349 1 341
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.83e-95 1 344 1 333
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 8.87e-44 3 317 4 310
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18375574931111301481671862042232412602792973163343531363ACV56058.1|GT281362BAK44146.1|GT281363QOS67217.1|GT281363QTU84759.1|GT281366BAN77391.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
ACV56058.1 1.88e-203 1 363 1 363
BAK44146.1 1.52e-200 1 362 1 362
QOS67217.1 8.44e-200 1 363 1 363
QTU84759.1 2.23e-186 1 363 1 363
BAN77391.1 2.89e-167 1 366 1 366

PDB Hits      download full data without filtering help

Created with Snap183755749311113014816718620422324126027929731633435333633S2U_A33307D1I_A33121F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 1.70e-51 3 363 5 355
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 5.01e-50 3 330 12 334
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 1.05e-40 3 312 9 305
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343531340sp|B8CWJ6|MURG_HALOH1340sp|A3DE27|MURG_ACET21362sp|B1MXW0|MURG_LEUCK1359sp|Q03W35|MURG_LEUMM1351sp|B8FT56|MURG_DESHD
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B8CWJ6 5.91e-73 1 340 1 345
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=murG PE=3 SV=1
A3DE27 5.43e-70 1 340 1 340
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
B1MXW0 4.27e-69 1 362 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Leuconostoc citreum (strain KM20) OX=349519 GN=murG PE=3 SV=1
Q03W35 2.01e-68 1 359 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) OX=203120 GN=murG PE=3 SV=1
B8FT56 4.72e-68 1 351 1 355
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfitobacterium hafniense (strain DSM 10664 / DCB-2) OX=272564 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000032 0.000034 0.000002 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000767_00682.