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CAZyme Information: MGYG000000929_00211

You are here: Home > Sequence: MGYG000000929_00211

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-273 sp000437855
Lineage Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-273; CAG-273 sp000437855
CAZyme ID MGYG000000929_00211
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
370 MGYG000000929_3|CGC1 41145.78 9.8252
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000929 1183274 MAG Germany Europe
Gene Location Start: 34714;  End: 35826  Strand: -

Full Sequence      Download help

MRVIIAAAGT  GGHINPGIAI  ANEIKRQEPN  SEIIFVGTNR  GLENDLVPRA  GYKLEHINAY60
GFDRTISIEN  IKKIYQTFHS  IKEAKKIIEQ  FKPDVVIGTG  GYICVPIGIA  AQKRKVPVVL120
HESNAFPGVA  VKILSNKAKK  VLVGFEDTKK  RLPKAKQVVV  TGTPTKVKKV  KISEERKKEL180
LKENKLNDNK  PIVLFFGGSQ  GAKSINDSLL  EIISKKQNQN  YQILWAAGPA  QYEKIKNELK240
EKYSIEIDNI  EDVSIVPYIY  NMEEIMNIVD  LVVSRSGAMT  ITEIANVGVP  AIFIPFPFAT300
ENHQEYNAKV  LENVGAAKII  LDKNLTSNEL  NSTITNLVEN  KNALKDMGKK  ANQVAIQNVE360
EKIYKEIKEL  370

Enzyme Prediction      help

No EC number prediction in MGYG000000929_00211.

CAZyme Signature Domains help

Created with Snap1837557492111129148166185203222240259277296314333351193357GT28
Family Start End Evalue family coverage
GT28 193 357 3e-50 0.9745222929936306

CDD Domains      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333511370murG2366GT28_MurG1370MurG1367murG192363Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 5.58e-140 1 370 2 354
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.54e-131 2 366 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.38e-110 1 370 1 354
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.76e-109 1 367 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam04101 Glyco_tran_28_C 3.06e-43 192 363 1 166
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap18375574921111291481661852032222402592772963143333511370ABY94470.1|GT281370ABY93281.1|GT281370ADV79423.1|GT281370AEV68995.1|GT281370ADU74308.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
ABY94470.1 7.03e-100 1 370 1 363
ABY93281.1 7.03e-100 1 370 1 363
ADV79423.1 7.03e-100 1 370 1 363
AEV68995.1 7.26e-100 1 370 1 362
ADU74308.1 3.31e-99 1 370 1 362

PDB Hits      download full data without filtering help

Created with Snap183755749211112914816618520322224025927729631433335123587D1I_A23553S2U_A23671F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 9.93e-49 2 358 11 353
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 2.18e-46 2 355 4 339
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 3.57e-42 2 367 8 350
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333511370sp|B0K8K7|MURG_THEP31370sp|B0K3H0|MURG_THEPX1370sp|A3DE27|MURG_ACET21368sp|Q8R9G6|MURG_CALS41354sp|A4J2B1|MURG_DESRM
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B0K8K7 1.41e-100 1 370 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B0K3H0 1.41e-100 1 370 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
A3DE27 6.62e-100 1 370 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
Q8R9G6 1.51e-94 1 368 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1
A4J2B1 3.89e-94 1 354 1 351
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000058 0.000003 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000929_00211.