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CAZyme Information: MGYG000000998_00017

You are here: Home > Sequence: MGYG000000998_00017

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species TM7x sp900556885
Lineage Bacteria; Patescibacteria; Saccharimonadia; Saccharimonadales; Saccharimonadaceae; TM7x; TM7x sp900556885
CAZyme ID MGYG000000998_00017
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
370 MGYG000000998_1|CGC1 40972.79 10.1095
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000998 635891 MAG China Asia
Gene Location Start: 15345;  End: 16457  Strand: +

Full Sequence      Download help

MVAVFRELQK  TGDHELRFWC  DKKFGVSARG  IFAKFDENIP  VDLIIAGKLR  RYHGKSISLH60
LHPSILFPNL  RDGFKVLIGF  FQSLFKLMKW  RPDVIFIKGG  YVCLPVGYAA  RLLRIPLVLH120
DSDAHPGLTN  RLLSPFAKAI  GTGAPLEYYN  YPPEKASYVG  IPVAPEFHPY  SEAERKELKE180
KLGFNVNKPL  VVITGGGLGA  GRINSAIVAI  RENLLAEASV  FLISGNQQYE  EILEQTDERE240
GWRLQAFVHN  GMAEVLAAAD  IVVTRAGATT  LLELAALHKP  TIIIPNGHLT  GGHQLKNAKV300
YQDALAALIV  SEDELDKDNQ  ILARKIIGVL  KSQKILKGLG  DNFGKFAKPN  AAKDMAKIIL360
TTVRRQGRRK  370

Enzyme Prediction      help

No EC number prediction in MGYG000000998_00017.

CAZyme Signature Domains help

Created with Snap1837557492111129148166185203222240259277296314333351191351GT28
Family Start End Evalue family coverage
GT28 191 351 9.9e-37 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333512365murG2358GT28_MurG2365MurG37315PRK12446190355Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 6.47e-93 2 365 19 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 2.53e-80 2 358 17 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 6.43e-80 2 365 18 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
PRK12446 PRK12446 4.37e-42 37 315 49 310
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed
pfam04101 Glyco_tran_28_C 1.77e-28 190 355 1 166
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap18375574921111291481661852032222402592772963143333511370AJA06770.1|GT281370QCT41397.1|GT281370QHU93683.1|GT281370QHU91979.1|GT281370QLF51712.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
AJA06770.1 2.36e-245 1 370 18 387
QCT41397.1 2.55e-245 1 370 20 389
QHU93683.1 1.70e-201 1 370 18 387
QHU91979.1 6.89e-201 1 370 18 387
QLF51712.1 3.97e-200 1 370 18 387

PDB Hits      download full data without filtering help

Created with Snap183755749211112914816618520322224025927729631433335123597D1I_A753643S2U_A873181F0K_A873514WYI_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 1.15e-22 2 359 27 362
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 2.65e-19 75 364 76 356
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.55e-16 87 318 91 313
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
4WYI_A 7.94e-09 87 351 103 372
Thecrystal structure of Arabidopsis thaliana galactolipid synthase, MGD1 (apo-form) [Arabidopsis thaliana],4X1T_A The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP [Arabidopsis thaliana]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333512359sp|C3L230|MURG_CLOB62359sp|C1FUF9|MURG_CLOBJ2359sp|B1IKH3|MURG_CLOBK2359sp|A7GGX9|MURG_CLOBL2359sp|A5I5J5|MURG_CLOBH
Hit ID E-Value Query Start Query End Hit Start Hit End Description
C3L230 1.91e-44 2 359 19 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain 657 / Type Ba4) OX=515621 GN=murG PE=3 SV=1
C1FUF9 2.68e-44 2 359 19 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Kyoto / Type A2) OX=536232 GN=murG PE=3 SV=1
B1IKH3 3.74e-44 2 359 19 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Okra / Type B1) OX=498213 GN=murG PE=3 SV=1
A7GGX9 3.74e-44 2 359 19 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) OX=441772 GN=murG PE=3 SV=1
A5I5J5 7.33e-44 2 359 19 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) OX=441771 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000056 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000998_00017.