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CAZyme Information: MGYG000001291_00675

You are here: Home > Sequence: MGYG000001291_00675

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Finegoldia magna_H
Lineage Bacteria; Firmicutes_A; Clostridia; Tissierellales; Peptoniphilaceae; Finegoldia; Finegoldia magna_H
CAZyme ID MGYG000001291_00675
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
370 MGYG000001291_1|CGC8 41520.47 8.8783
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001291 1986740 Isolate not provided not provided
Gene Location Start: 681315;  End: 682427  Strand: +

Full Sequence      Download help

MNIIVSGGGT  GGHIYPAISL  IEELKKRDKD  NKILYVGTEK  GLESSIVPKL  GIDFKTIHVR60
GIPRKINANS  FKALKELFQG  LREANKILKE  FKPDLVIGTG  GYVSGPILYK  ATKTKAKVAF120
HEQNSFPGIT  NRILSRYVDK  YFVTFKESIK  YFKNQDKAVV  TGNPIRNRFT  DIEKNKKSAL180
EQYDISENKK  VVFIFGGSNG  SEILNKATLN  MIEKISNQDK  FEIVLATGKL  NYDEFIQQSG240
KEIKNLHVYP  YIDDIDKAYA  VSDLIVTSSG  AITLAELSFL  GKASILVPKA  YTTENHQEHN300
ARAFEKNGAS  KVILEKDLNS  DTLFDQINEI  LSDDNLLNEL  SENSKKMSYP  TACKDIVDEL360
YRLVEQDEKA  370

Enzyme Prediction      help

No EC number prediction in MGYG000001291_00675.

CAZyme Signature Domains help

Created with Snap1837557492111129148166185203222240259277296314333351192351GT28
Family Start End Evalue family coverage
GT28 192 351 4e-46 0.9808917197452229

CDD Domains      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333513359GT28_MurG1365murG1366MurG1360murG3143Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03785 GT28_MurG 2.18e-148 3 359 2 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
PRK00726 murG 8.07e-142 1 365 2 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
COG0707 MurG 1.04e-111 1 366 1 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 4.29e-101 1 360 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 1.54e-44 3 143 1 139
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18375574921111291481661852032222402592772963143333511370BAG08035.1|GT281370QKH79845.1|GT281362QQK07511.1|GT281361AXU11211.1|GT281361AIZ37231.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
BAG08035.1 1.12e-264 1 370 1 370
QKH79845.1 5.30e-263 1 370 1 370
QQK07511.1 1.54e-149 1 362 1 363
AXU11211.1 5.84e-148 1 361 1 363
AIZ37231.1 5.84e-148 1 361 1 363

PDB Hits      download full data without filtering help

Created with Snap183755749211112914816618520322224025927729631433335123583S2U_A23637D1I_A33631F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 4.75e-50 2 358 4 349
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 3.51e-43 2 363 11 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 4.99e-42 3 363 9 353
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333511370sp|B0S0Z5|MURG_FINM21358sp|A3DE27|MURG_ACET21370sp|Q182Y6|MURG_CLOD61365sp|Q8R9G6|MURG_CALS41357sp|A4J2B1|MURG_DESRM
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B0S0Z5 2.23e-265 1 370 1 370
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508) OX=334413 GN=murG PE=3 SV=1
A3DE27 2.96e-114 1 358 1 357
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
Q182Y6 1.90e-106 1 370 2 372
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridioides difficile (strain 630) OX=272563 GN=murG PE=3 SV=1
Q8R9G6 3.82e-103 1 365 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1
A4J2B1 3.97e-102 1 357 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000074 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001291_00675.