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CAZyme Information: MGYG000001625_00370

You are here: Home > Sequence: MGYG000001625_00370

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Eikenella corrodens
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Neisseriaceae; Eikenella; Eikenella corrodens
CAZyme ID MGYG000001625_00370
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
356 MGYG000001625_22|CGC1 37317.17 8.8134
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001625 1812730 MAG China Asia
Gene Location Start: 4938;  End: 6008  Strand: -

Full Sequence      Download help

MGVKTFLLMA  GGTGGHIFPA  LAVAAALRER  GHKVVWLGSE  GAMETRIVPQ  HGIEIETLAI60
KGVRGNGLKR  KLMLPFTLWH  TIRAARSIIR  KHQVDGAIGF  GGFVTVPGGV  AAKLCGVPLV120
IHEQNAVAGL  SNRILAKLAS  RVLYAFPKAF  GDENGLVGNP  VRADIAALPA  PEERFAERLG180
SLKLLVTGGS  LGADILNRLL  PEALALLPAE  QRPEVRHQSG  RGKLEGLRQR  YDEAGVQAEC240
SEFIDDMAAA  YGTADLVVCR  SGALTIAELA  AAGVGALLVP  YPYAVDDHQT  ANARFVAAGE300
AGLLLPQSEL  TAEKLASVLG  GLNRDTCRQW  AQNARQMAKP  DSAAKVAEAA  LAAVGG356

Enzyme Prediction      help

No EC number prediction in MGYG000001625_00370.

CAZyme Signature Domains help

Created with Snap1735537189106124142160178195213231249267284302320338184341GT28
Family Start End Evalue family coverage
GT28 184 341 1.6e-48 0.9808917197452229

CDD Domains      download full data without filtering help

Created with Snap17355371891061241421601781952132312492672843023203384342murG4342murG6342GT28_MurG4342MurG6143Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 9.00e-154 4 342 2 343
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
TIGR01133 murG 7.72e-134 4 342 1 340
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
cd03785 GT28_MurG 7.15e-132 6 342 2 343
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 8.41e-123 4 342 1 343
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
pfam03033 Glyco_transf_28 2.94e-45 6 143 1 138
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap17355371891061241421601781952132312492672843023203381356QED91463.1|GT281356SNW07245.1|GT281356AZR59298.1|GT281354QMT40752.1|GT281353ASP18024.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QED91463.1 3.24e-250 1 356 1 356
SNW07245.1 7.01e-245 1 356 1 356
AZR59298.1 1.41e-244 1 356 1 356
QMT40752.1 2.30e-199 1 354 1 354
ASP18024.1 6.13e-186 1 353 1 353

PDB Hits      download full data without filtering help

Created with Snap173553718910612414216017819521323124926728430232033873513S2U_A43471F0K_A43487D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 9.28e-101 7 351 6 352
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 2.33e-98 4 347 7 347
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 9.59e-87 4 348 10 360
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap17355371891061241421601781952132312492672843023203381352sp|A9M2H3|MURG_NEIM01352sp|Q9JSZ7|MURG_NEIMA1352sp|Q9K0Y2|MURG_NEIMB1352sp|Q5F6L8|MURG_NEIG11352sp|B4RQC5|MURG_NEIG2
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A9M2H3 1.67e-179 1 352 1 352
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Neisseria meningitidis serogroup C (strain 053442) OX=374833 GN=murG PE=3 SV=1
Q9JSZ7 4.79e-179 1 352 1 352
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491) OX=122587 GN=murG PE=3 SV=1
Q9K0Y2 9.65e-179 1 352 1 352
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=murG PE=3 SV=1
Q5F6L8 2.76e-178 1 352 1 352
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) OX=242231 GN=murG PE=3 SV=1
B4RQC5 2.76e-178 1 352 1 352
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Neisseria gonorrhoeae (strain NCCP11945) OX=521006 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000087 0.000002 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001625_00370.