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CAZyme Information: MGYG000001764_00209

You are here: Home > Sequence: MGYG000001764_00209

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA1206 sp000433115
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-382; UBA1206; UBA1206 sp000433115
CAZyme ID MGYG000001764_00209
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
370 MGYG000001764_4|CGC1 40737.19 9.8502
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001764 1921530 MAG Denmark Europe
Gene Location Start: 28900;  End: 30012  Strand: -

Full Sequence      Download help

MRVLMCGGGT  GGHINPALAI  ANEIKRREPD  SVIEFVGTTH  GLEGKLVPEA  GYKLHTVKVQ60
GFRRKLTLKN  VKALVYAATS  VFEARRIIKK  FNPDVVIGTG  GYASWPTVKA  ATELHIPTLI120
QEQNAFPGVT  TKKLSKYVDK  VCISFEGSEQ  YFDQAVRGKL  VLTGNPVKPN  CFEKAEARRK180
LGIKDDEIYI  LSSGGSLGAD  KVNTFVLDAM  NIYRDKKGIR  QTHAVGHIGW  EKFSAVIKEK240
KLDECPQFEI  LEYIYDMQLR  QAAADVVISR  AGAITTAELA  LIGRATIFIP  SPNVAEDHQY300
KNAMVLKNAD  AADVIKESVL  DGRILAKTVM  DLSADGEKRR  RMENNMRAFG  KPNATKKIVD360
LIFELTASGK  370

Enzyme Prediction      help

No EC number prediction in MGYG000001764_00209.

CAZyme Signature Domains help

Created with Snap1837557492111129148166185203222240259277296314333351190354GT28
Family Start End Evalue family coverage
GT28 190 354 1.2e-39 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333511368murG2361GT28_MurG1362MurG1362murG3141Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 7.67e-134 1 368 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 2.41e-125 2 361 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 8.98e-106 1 362 1 351
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 5.57e-99 1 362 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 1.14e-37 3 141 1 137
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18375574921111291481661852032222402592772963143333511365AUS96129.1|GT281365QAT50143.1|GT281360QIB70094.1|GT281365ADU74308.1|GT281365ABN52206.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
AUS96129.1 1.00e-92 1 365 1 362
QAT50143.1 3.53e-92 1 365 1 369
QIB70094.1 3.54e-92 1 360 1 360
ADU74308.1 8.03e-92 1 365 1 362
ABN52206.1 8.03e-92 1 365 1 362

PDB Hits      download full data without filtering help

Created with Snap183755749211112914816618520322224025927729631433335123653S2U_A23627D1I_A23601F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 5.04e-54 2 365 4 354
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 3.36e-44 2 362 11 362
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 4.60e-44 2 360 8 348
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574921111291481661852032222402592772963143333511365sp|A3DE27|MURG_ACET21362sp|A4J2B1|MURG_DESRM1366sp|B0K8K7|MURG_THEP31366sp|B0K3H0|MURG_THEPX1366sp|Q8R9G6|MURG_CALS4
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DE27 1.61e-92 1 365 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
A4J2B1 2.07e-85 1 362 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=murG PE=3 SV=1
B0K8K7 9.15e-85 1 366 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B0K3H0 9.15e-85 1 366 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
Q8R9G6 1.83e-84 1 366 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000060 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001764_00209.