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CAZyme Information: MGYG000002269_00693

You are here: Home > Sequence: MGYG000002269_00693

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Anaerococcus nagyae
Lineage Bacteria; Firmicutes_A; Clostridia; Tissierellales; Peptoniphilaceae; Anaerococcus; Anaerococcus nagyae
CAZyme ID MGYG000002269_00693
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
361 MGYG000002269_2|CGC4 39695.46 9.1011
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002269 1825027 Isolate China Asia
Gene Location Start: 274304;  End: 275389  Strand: +

Full Sequence      Download help

MRVIISGGGT  GGHIYPAIAI  AQKIEENISN  TKVLYVGIKG  GPEESIAEKY  GYEFRPIDGM60
GMPRKINKKF  FKSLSRNMKG  FKAARKIVKD  FKPDIAIGTG  GYVCGPIIFQ  AAKAGVPTLI120
HESNSYPGVT  SKFLSNKVDA  LCISYKEAKK  YFKHKENIIV  TGNPVRTNFS  SYYTNEDLES180
LGIKKDIPVV  FSFGGSNGSY  AMNKAVKEMA  NSLKGDFYLL  HQTGKKNYDD  FISNLDQNSY240
LKVFPYIDNI  DLFYAVSDLV  IASSGAMSLA  EISSVKKPSI  LIPKAYTTEN  HQQHNAQTYV300
DNGAAMMILE  KDLNGKILYD  NIISVITNND  KLTEMGEASS  KLSNDGASDT  IFELIVDLTA360
R361

Enzyme Prediction      help

No EC number prediction in MGYG000002269_00693.

CAZyme Signature Domains help

Created with Snap1836547290108126144162180198216234252270288306324342190344GT28
Family Start End Evalue family coverage
GT28 190 344 6.3e-45 0.9681528662420382

CDD Domains      download full data without filtering help

Created with Snap18365472901081261441621801982162342522702883063243421361murG2354GT28_MurG1355MurG1355murG3140Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 6.92e-131 1 361 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.27e-129 2 354 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.93e-101 1 355 1 351
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.16e-98 1 355 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 1.02e-41 3 140 1 136
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18365472901081261441621801982162342522702883063243421358ACV29227.1|GT281355QQN56060.1|GT281355QQB61390.1|GT281357AXU11211.1|GT281357AIZ37231.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
ACV29227.1 8.22e-180 1 358 1 358
QQN56060.1 7.26e-178 1 355 1 355
QQB61390.1 7.26e-178 1 355 1 355
AXU11211.1 4.32e-113 1 357 1 364
AIZ37231.1 4.32e-113 1 357 1 364

PDB Hits      download full data without filtering help

Created with Snap183654729010812614416218019821623425227028830632434223557D1I_A23583S2U_A23131F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 8.54e-40 2 355 11 362
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 9.20e-36 2 358 4 354
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 2.43e-35 2 313 8 310
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365472901081261441621801982162342522702883063243421361sp|B0S0Z5|MURG_FINM21358sp|A3DE27|MURG_ACET21361sp|A8MH36|MURG_ALKOO1358sp|B8I6H3|MURG_RUMCH1359sp|B0K8K7|MURG_THEP3
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B0S0Z5 2.90e-112 1 361 1 366
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508) OX=334413 GN=murG PE=3 SV=1
A3DE27 1.11e-98 1 358 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
A8MH36 4.59e-97 1 361 1 365
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus oremlandii (strain OhILAs) OX=350688 GN=murG PE=3 SV=1
B8I6H3 9.80e-96 1 358 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=murG PE=3 SV=1
B0K8K7 7.87e-95 1 359 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000083 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002269_00693.