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CAZyme Information: MGYG000002284_00758

You are here: Home > Sequence: MGYG000002284_00758

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Megamonas funiformis
Lineage Bacteria; Firmicutes_C; Negativicutes; Selenomonadales; Selenomonadaceae; Megamonas; Megamonas funiformis
CAZyme ID MGYG000002284_00758
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
372 MGYG000002284_7|CGC1 40600.3 9.6633
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002284 2244659 Isolate China Asia
Gene Location Start: 11800;  End: 12918  Strand: -

Full Sequence      Download help

MRIIVSGGGT  GGHIYPAITL  INNIKKLVPN  AEFLYVGTKK  GLEADIIPRE  QIPFVTLDIS60
GFERHLTMKN  FVVAGKALRA  VMKARSIVKN  FKPDVAIGTG  GYVCGPILMA  ASLMGIPALI120
QEQNAIPGVT  NKILARFVDK  IAVGYKRALS  YFPENKVVFT  GNPIRDDILL  STRNEGLMEF180
SLDTTKKTIL  VSGGSRGAHS  INKAMLEVHK  HFANNYRVQI  MHVTGKNEYD  FVKNGLADLG240
VNLDKVDNLA  VYPYLYDMPK  ALAATDIAVF  RAGATSLAEL  TARGVPAVLI  PYPFAAENHQ300
EFNARELEKN  GAAKVILNRE  LTGEKLINVL  EEMLASENRL  QEMVEASRNM  GKPSAALAIA360
EMVVDLAKKT  NY372

Enzyme Prediction      help

No EC number prediction in MGYG000002284_00758.

CAZyme Signature Domains help

Created with Snap1837557493111130148167186204223241260279297316334353188355GT28
Family Start End Evalue family coverage
GT28 188 355 1e-52 0.9936305732484076

CDD Domains      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343531369murG2362GT28_MurG1369MurG1361murG2333PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 9.33e-150 1 369 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.61e-141 2 362 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.82e-119 1 369 1 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.03e-111 1 361 1 346
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 4.06e-50 2 333 3 322
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18375574931111301481671862042232412602792973163343531372BDA09789.1|GT281372QIB59632.1|GT281368SNU99494.1|GT281309CBL06308.1|GT281372QJW46500.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
BDA09789.1 6.46e-265 1 372 1 372
QIB59632.1 2.63e-264 1 372 1 372
SNU99494.1 2.57e-225 1 368 1 368
CBL06308.1 4.62e-217 1 309 1 309
QJW46500.1 1.21e-156 1 372 1 373

PDB Hits      download full data without filtering help

Created with Snap183755749311113014816718620422324126027929731633435323723S2U_A23721F0K_A23697D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 6.94e-55 2 372 4 360
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 2.17e-52 2 372 8 359
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 2.38e-51 2 369 11 364
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343531368sp|A5D145|MURG_PELTS1363sp|A4J2B1|MURG_DESRM1366sp|A8FCY1|MURG_BACP21368sp|P37585|MURG_BACSU1369sp|Q812W5|MURG1_BACCR
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A5D145 4.25e-121 1 368 1 369
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) OX=370438 GN=murG PE=3 SV=1
A4J2B1 4.41e-120 1 363 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=murG PE=3 SV=1
A8FCY1 2.21e-118 1 366 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacillus pumilus (strain SAFR-032) OX=315750 GN=murG PE=3 SV=1
P37585 2.81e-116 1 368 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacillus subtilis (strain 168) OX=224308 GN=murG PE=3 SV=3
Q812W5 3.33e-115 1 369 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1 OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) OX=226900 GN=murG1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000057 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002284_00758.