logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000002686_01192

You are here: Home > Sequence: MGYG000002686_01192

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; QAMH01; QAMH01;
CAZyme ID MGYG000002686_01192
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
369 MGYG000002686_81|CGC1 39069.65 5.9942
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002686 1530597 MAG Canada North America
Gene Location Start: 1816;  End: 2925  Strand: -

Full Sequence      Download help

MYYVIAAGGT  AGHINPALAV  ADELRRRGHE  ILFVGTPNHI  ESRLATQAGF  EFMGFAVSGF60
DKAHPLTLVS  SGAKLLKATR  AAKKLFKSKH  PDAVVTFGAY  VSIPVGRAAF  EMGIPLIIHE120
QNSVPGMANA  YLAKHATAIA  LTYAESAQGL  EGACEPVVLG  NPVRASFETC  TRDQARASLG180
IPDDALILLV  MGGSLGAQHV  NKAICDMKER  LLAIDGLHVI  QSTGESDYEN  VLAQLDLGDE240
EQKRWRVSPY  IDSMNEALVA  SDLVVSRSGA  SSVAEIMTVG  VPSVLIPYPY  ARGDHQTLNA300
QSCVAVGAAC  LVADADVESA  GFSDLLIELL  GDKARRDTMT  QACKKLSGSD  ARMRLADMVE360
KCARGNDGS369

Enzyme Prediction      help

No EC number prediction in MGYG000002686_01192.

CAZyme Signature Domains help

Created with Snap1836557392110129147166184202221239258276295313332350188350GT28
Family Start End Evalue family coverage
GT28 188 350 5.1e-47 0.9808917197452229

CDD Domains      download full data without filtering help

Created with Snap18365573921101291471661842022212392582762953133323501365murG4358GT28_MurG4365MurG4357murG4359PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 6.53e-129 1 365 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 9.21e-122 4 358 3 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 2.05e-102 4 365 4 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 3.48e-98 4 357 4 346
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 8.87e-39 4 359 5 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18365573921101291471661842022212392582762953133323501364QTU84759.1|GT281364VEG99762.1|GT281364ACV21932.1|GT281364QOS67217.1|GT281363AJC12321.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QTU84759.1 8.38e-128 1 364 1 364
VEG99762.1 7.56e-123 1 364 1 364
ACV21932.1 7.56e-123 1 364 1 364
QOS67217.1 4.15e-120 1 364 1 364
AJC12321.1 3.00e-119 1 363 1 363

PDB Hits      download full data without filtering help

Created with Snap183655739211012914716618420222123925827629531333235043653S2U_A43641F0K_A23617D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 9.67e-49 4 365 6 357
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.48e-46 4 364 10 355
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 1.52e-46 2 361 11 364
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573921101291471661842022212392582762953133323501366sp|B8CWJ6|MURG_HALOH1358sp|Q24TE6|MURG_DESHY1360sp|A3DE27|MURG_ACET21362sp|B8FT56|MURG_DESHD1363sp|B1I4C4|MURG_DESAP
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B8CWJ6 1.09e-75 1 366 1 371
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=murG PE=3 SV=1
Q24TE6 2.49e-70 1 358 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfitobacterium hafniense (strain Y51) OX=138119 GN=murG PE=3 SV=1
A3DE27 4.95e-70 1 360 1 360
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
B8FT56 2.76e-69 1 362 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfitobacterium hafniense (strain DSM 10664 / DCB-2) OX=272564 GN=murG PE=3 SV=1
B1I4C4 1.06e-66 1 363 1 368
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulforudis audaxviator (strain MP104C) OX=477974 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000047 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002686_01192.