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CAZyme Information: MGYG000002736_00500

You are here: Home > Sequence: MGYG000002736_00500

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UMGS403 sp900541565
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UMGS403; UMGS403 sp900541565
CAZyme ID MGYG000002736_00500
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
375 MGYG000002736_4|CGC1 40613.15 9.6918
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002736 2234011 MAG Netherlands Europe
Gene Location Start: 39066;  End: 40193  Strand: -

Full Sequence      Download help

MRVLFAGGGT  AGHINPALAV  AGYIRKKEPD  VQILYVGAKG  GMEERLVPQA  GFAFEGISVS60
GFKRSFSPSA  VKDNIITVKK  ALQAGTVSKR  IIRDFKPDIC  MGTGGYVSGP  VIRAAAKLSI120
PTVIHEQNAF  PGVTTKMLSR  YVKRVMLAMP  EAKQYLSDGC  RCVTTGNPVR  QEILTADKTA180
CRKKLGLDSR  PVVLSFGGSL  GARKINENVA  GMIARSAKDG  KYQIIHAYGQ  YGKWFPDLLR240
KMGADPDGCE  NLDIREYIDD  MPVCLAAADL  VICRAGAITL  SELQAQGKPA  ILIPSPNVAE300
NHQYHNAMAM  ANRQAARVLK  EEELTQEAVM  QAVDDMVSDP  EKLRKYSENA  KRLAITDANE360
RIYSVIKKVL  GTAAV375

Enzyme Prediction      help

No EC number prediction in MGYG000002736_00500.

CAZyme Signature Domains help

Created with Snap1837567593112131150168187206225243262281300318337356193358GT28
Family Start End Evalue family coverage
GT28 193 358 5.6e-50 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18375675931121311501681872062252432622813003183373562365GT28_MurG1371murG1369MurG1366murG2369PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03785 GT28_MurG 8.17e-144 2 365 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
PRK00726 murG 1.05e-141 1 371 2 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
COG0707 MurG 2.48e-114 1 369 1 354
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.22e-107 1 366 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 1.53e-50 2 369 3 352
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18375675931121311501681872062252432622813003183373561371QCT06982.1|GT281370CAB1239505.1|GT281371QEY33586.1|GT281370QAT50143.1|GT281371QNK41610.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QCT06982.1 9.84e-182 1 371 1 371
CAB1239505.1 4.22e-170 1 370 1 370
QEY33586.1 2.93e-167 1 371 1 371
QAT50143.1 1.25e-164 1 370 1 370
QNK41610.1 1.25e-164 1 371 1 371

PDB Hits      download full data without filtering help

Created with Snap183756759311213115016818720622524326228130031833735623693S2U_A23691F0K_A23697D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 7.13e-51 2 369 4 354
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.37e-50 2 369 8 353
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 3.64e-45 2 369 11 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375675931121311501681872062252432622813003183373561374sp|A3DE27|MURG_ACET21370sp|B8I6H3|MURG_RUMCH1369sp|B0K3H0|MURG_THEPX1369sp|B0K8K7|MURG_THEP31370sp|O07670|MURG_ENTHR
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DE27 3.26e-112 1 374 1 367
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
B8I6H3 3.81e-99 1 370 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=murG PE=3 SV=1
B0K3H0 8.96e-95 1 369 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
B0K8K7 8.96e-95 1 369 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
O07670 2.54e-93 1 370 1 358
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Enterococcus hirae OX=1354 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000061 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002736_00500.