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CAZyme Information: MGYG000002807_00397

You are here: Home > Sequence: MGYG000002807_00397

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Eubacterium_R sp900539165
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Eubacterium_R; Eubacterium_R sp900539165
CAZyme ID MGYG000002807_00397
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
379 MGYG000002807_4|CGC1 41462.7 6.5782
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002807 1764558 MAG Peru South America
Gene Location Start: 25105;  End: 26244  Strand: -

Full Sequence      Download help

MRFLFATGGT  AGHINPALAV  ASYIREKYPE  SEILFIGTKD  HMESRLVPNA  GFDFKTIEIN60
GFKRSMAPKA  IVANVKTVFK  LIKSEQASKN  IIKEFNPDVV  IGFGGYVSGP  VLEEAAKLHI120
PCCIHEQNAF  PGITNKQLAK  KVDKVMLTVE  DAVRHLQPKH  EVAVTGLPVR  GELLNKSKAQ180
ARIELGIADD  TPLVLSFGGS  LGAAPLNDAM  FDILKENAIT  SKAYHIHSVG  TNGMEYLKKF240
EAEGFIKRSD  NVLYKGKSEV  RLYIDNMDTC  MAAADLVVGR  AGASSLSEIE  AMGKASVLIP300
SPYVAENHQY  HNAMALVNRN  AARILEEKDL  TTESLKELID  SLLSDKDELH  KIENNARDMA360
ILDSAERISD  IIVSLAKDN379

Enzyme Prediction      help

No EC number prediction in MGYG000002807_00397.

CAZyme Signature Domains help

Created with Snap1837567594113132151170189208227246265284303322341360194361GT28
Family Start End Evalue family coverage
GT28 194 361 1.7e-44 0.9681528662420382

CDD Domains      download full data without filtering help

Created with Snap18375675941131321511701892082272462652843033223413601377murG2371GT28_MurG1377MurG1372murG3146Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 1.37e-137 1 377 2 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.60e-127 2 371 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 3.55e-100 1 377 1 356
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 4.95e-98 1 372 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 4.10e-39 3 146 1 138
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18375675941131321511701892082272462652843033223413601372QCT06982.1|GT281379QEY33586.1|GT281372QNK41610.1|GT281378QKO29751.1|GT281378QKN23573.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QCT06982.1 1.20e-130 1 372 1 366
QEY33586.1 6.82e-123 1 379 1 373
QNK41610.1 6.10e-122 1 372 1 366
QKO29751.1 8.65e-122 1 378 1 372
QKN23573.1 8.65e-122 1 378 1 372

PDB Hits      download full data without filtering help

Created with Snap183756759411313215117018920822724626528430332234136023771F0K_A43727D1I_A43773S2U_A1613054WYI_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 5.74e-44 2 377 8 355
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 1.60e-43 4 372 13 362
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 3.24e-42 4 377 6 356
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
4WYI_A 5.83e-06 161 305 179 317
Thecrystal structure of Arabidopsis thaliana galactolipid synthase, MGD1 (apo-form) [Arabidopsis thaliana],4X1T_A The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP [Arabidopsis thaliana]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375675941131321511701892082272462652843033223413601378sp|A3DE27|MURG_ACET21377sp|A7GRN6|MURG_BACCN1377sp|Q812W5|MURG1_BACCR1375sp|B0K8K7|MURG_THEP31375sp|B0K3H0|MURG_THEPX
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DE27 1.16e-97 1 378 1 365
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
A7GRN6 2.63e-92 1 377 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) OX=315749 GN=murG PE=3 SV=1
Q812W5 5.26e-92 1 377 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1 OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) OX=226900 GN=murG1 PE=3 SV=1
B0K8K7 2.11e-91 1 375 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B0K3H0 2.11e-91 1 375 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000042 0.000008 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002807_00397.