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CAZyme Information: MGYG000002830_00176

You are here: Home > Sequence: MGYG000002830_00176

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Veillonella sp900552715
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Veillonellaceae; Veillonella; Veillonella sp900552715
CAZyme ID MGYG000002830_00176
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
369 MGYG000002830_5|CGC1 39543.75 8.0872
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002830 1874743 MAG Singapore Asia
Gene Location Start: 8950;  End: 10059  Strand: -

Full Sequence      Download help

MKRIIISGGG  TGGHIYPAIT  IYKEIMKQNP  DAQVLYVGTE  KGLEATLVPK  EGIEFTTLPV60
QGLQRKLSFG  TLVTLGKTAF  SLVKANTIIS  NFKPDVVIGT  GGYVCGPILM  AAALRNIPTL120
IQEQNVIAGI  TNKILSRFVD  VVAVGYKDAE  ASFSKAKRVV  YTGNPVRPDV  LVDTRADGRN180
YFNLSDDTFT  VLIAGGSRGA  RTINNAMIDV  HKHFQGTKGI  KLIHITGDGE  YKSVLSQLGI240
TDGDGLGDSS  VILPYLHDMP  KALAAADLAV  FRSGAIGLAE  LAVRGIPSVL  VPYPYAAEDH300
QTYNARIFVQ  EGAAHMIVDQ  MLSAHDLIGE  IEMFMANRDL  LSQMGERALQ  LGKPNAAHDI360
AKLALSIAK369

Enzyme Prediction      help

No EC number prediction in MGYG000002830_00176.

CAZyme Signature Domains help

Created with Snap1836557392110129147166184202221239258276295313332350190356GT28
Family Start End Evalue family coverage
GT28 190 356 2e-47 0.9936305732484076

CDD Domains      download full data without filtering help

Created with Snap183655739211012914716618420222123925827629531333235016369murG16363GT28_MurG16369MurG16364murG190360Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 1.82e-128 16 369 16 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 2.61e-123 16 363 14 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 9.28e-105 16 369 15 356
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.42e-92 16 364 15 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam04101 Glyco_tran_28_C 1.30e-37 190 360 1 166
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap18365573921101291471661842022212392582762953133323501369VEG93350.1|GT281369BBU34274.1|GT281369BBU36346.1|GT281369SNV68321.1|GT281369CAB1275410.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
VEG93350.1 5.72e-262 1 369 1 369
BBU34274.1 1.83e-258 1 369 1 369
BBU36346.1 1.83e-258 1 369 1 369
SNV68321.1 8.33e-239 1 369 1 369
CAB1275410.1 2.18e-234 1 369 1 369

PDB Hits      download full data without filtering help

Created with Snap183655739211012914716618420222123925827629531333235023637D1I_A33693S2U_A23691F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 1.91e-53 2 363 10 361
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 1.46e-52 3 369 4 356
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 5.10e-48 2 369 7 355
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573921101291471661842022212392582762953133323503367sp|Q8R9G6|MURG_CALS43367sp|B0K8K7|MURG_THEP33367sp|B0K3H0|MURG_THEPX3368sp|Q24TE6|MURG_DESHY3368sp|B8FT56|MURG_DESHD
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8R9G6 1.46e-110 3 367 2 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1
B0K8K7 1.18e-109 3 367 2 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B0K3H0 1.18e-109 3 367 2 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
Q24TE6 2.92e-106 3 368 2 367
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfitobacterium hafniense (strain Y51) OX=138119 GN=murG PE=3 SV=1
B8FT56 2.36e-105 3 368 2 367
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfitobacterium hafniense (strain DSM 10664 / DCB-2) OX=272564 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000059 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002830_00176.