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CAZyme Information: MGYG000002934_00720

You are here: Home > Sequence: MGYG000002934_00720

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Caproiciproducens sp900546895
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Caproiciproducens; Caproiciproducens sp900546895
CAZyme ID MGYG000002934_00720
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
373 MGYG000002934_37|CGC1 40888.44 9.5929
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002934 2823222 MAG Russia Europe
Gene Location Start: 5576;  End: 6697  Strand: -

Full Sequence      Download help

MKVLFAGGGT  AGHINPALAI  AGYLREKEPD  AQILYVGAKG  GMEERLVPAA  GFDFESITIS60
GFQRKLSWKN  IKKNVKTVVR  VFTSSREARK  IIGGFQPDLC  VGTGGYVAGP  VLREAMKMKI120
PAVIHEQNAF  PGVTNKMLSK  HADRTMLAVL  DAQKYLDPTA  RCVLTGNPVR  QAVIRANREE180
SRKALHLDER  PMILSFGGSL  GARKINEAVA  DLLVKSARTD  RFQHIHGYGQ  WGGWFPDLLK240
EKGLNLSEHP  RIDVREYINN  MPECLAAADL  VICRAGAISL  SELQAQGKAA  ILVPSPNVAE300
NHQYHNAMAM  VSRKAAAILE  EKDLSGPALC  KMVDDLFRQP  ETIRLLGENA  HSMAILDTNE360
RIYKIMKEVL  AGT373

Enzyme Prediction      help

No EC number prediction in MGYG000002934_00720.

CAZyme Signature Domains help

Created with Snap1837557493111130149167186205223242261279298317335354193355GT28
Family Start End Evalue family coverage
GT28 193 355 1.4e-43 0.9681528662420382

CDD Domains      download full data without filtering help

Created with Snap18375574931111301491671862052232422612792983173353541372murG2365GT28_MurG1372MurG1365murG2342PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 1.49e-131 1 372 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 9.61e-131 2 365 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.26e-107 1 372 1 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 5.46e-97 1 365 1 347
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 6.95e-45 2 342 3 328
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18375574931111301491671862052232422612792983173353541372QEY33586.1|GT281370QAT50143.1|GT281370CAB1239505.1|GT281370QNK41610.1|GT281370QKO29751.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QEY33586.1 7.09e-226 1 372 1 372
QAT50143.1 5.46e-203 1 370 1 370
CAB1239505.1 1.49e-200 1 370 1 370
QNK41610.1 2.33e-197 1 370 1 370
QKO29751.1 9.48e-197 1 370 1 370

PDB Hits      download full data without filtering help

Created with Snap183755749311113014916718620522324226127929831733535423621F0K_A23723S2U_A33397D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 1.21e-51 2 362 8 346
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
3S2U_A 5.80e-48 2 372 4 357
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 8.60e-36 3 339 12 336
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574931111301491671862052232422612792983173353541370sp|A3DE27|MURG_ACET21369sp|B0K3H0|MURG_THEPX1369sp|B0K8K7|MURG_THEP31370sp|B8I6H3|MURG_RUMCH1369sp|Q8R9G6|MURG_CALS4
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DE27 4.37e-104 1 370 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
B0K3H0 1.90e-93 1 369 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
B0K8K7 1.90e-93 1 369 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B8I6H3 2.15e-92 1 370 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=murG PE=3 SV=1
Q8R9G6 4.30e-92 1 369 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000067 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002934_00720.