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CAZyme Information: MGYG000003171_00332

You are here: Home > Sequence: MGYG000003171_00332

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-180 sp900540295
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; CAG-180; CAG-180 sp900540295
CAZyme ID MGYG000003171_00332
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
371 MGYG000003171_6|CGC1 39515.75 8.2704
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003171 1909791 MAG United States North America
Gene Location Start: 12979;  End: 14094  Strand: +

Full Sequence      Download help

MKIVFAAGGT  GGHINPALAV  AGELRRRDPK  TEILFIGTAD  HMESRLVPAA  GFAFQTIEIA60
GFQRKPTPQN  IVKNIKTVGL  LLKSTGAVKK  ILSDFAPDVA  VGFGGYVSGP  VVRTAAKMGI120
KTAIHEQNAY  PGVTNKALAK  KADKVMLTVE  AAKEHLSCPT  PPIVTGLPVR  REIVSANRDF180
ARAELHVPDD  AVMILSMGGS  LGAKAINEAM  TALIAARYTD  KNLFFLHATG  KYGKWVPEKL240
RENGVDSEKT  SNVVIREYID  NMDVCLAAAD  LVIGRAGASS  LSEIEATGKA  SVLIPSPNVA300
ENHQYHNAMA  LVNQDAAKII  EEKDLTPERL  IAVVDSLTQD  KSALRTLGEN  AKKMAVMDSA360
AVICDILTEL  A371

Enzyme Prediction      help

No EC number prediction in MGYG000003171_00332.

CAZyme Signature Domains help

Created with Snap1837557492111129148166185204222241259278296315333352194357GT28
Family Start End Evalue family coverage
GT28 194 357 1.9e-46 0.9745222929936306

CDD Domains      download full data without filtering help

Created with Snap18375574921111291481661852042222412592782963153333522366GT28_MurG1371murG1367murG1371MurG3146Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03785 GT28_MurG 3.39e-134 2 366 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
PRK00726 murG 1.29e-133 1 371 2 355
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
TIGR01133 murG 1.91e-106 1 367 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0707 MurG 3.74e-104 1 371 1 355
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
pfam03033 Glyco_transf_28 2.25e-40 3 146 1 138
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18375574921111291481661852042222412592782963153333521359QCT06982.1|GT281370CAB1250257.1|GT281370QKO29751.1|GT281370QKN23573.1|GT281370ARP50696.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QCT06982.1 2.54e-135 1 359 1 358
CAB1250257.1 4.60e-134 1 370 1 369
QKO29751.1 4.01e-128 1 370 1 369
QKN23573.1 4.01e-128 1 370 1 369
ARP50696.1 4.01e-128 1 370 1 369

PDB Hits      download full data without filtering help

Created with Snap183755749211112914816618520422224125927829631533335223711F0K_A23713S2U_A33707D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 5.69e-47 2 371 8 354
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
3S2U_A 8.59e-46 2 371 4 355
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 1.68e-45 3 370 12 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574921111291481661852042222412592782963153333521354sp|A4J2B1|MURG_DESRM1370sp|A3DE27|MURG_ACET21370sp|Q812W5|MURG1_BACCR1370sp|Q81JG5|MURG1_BACAN1370sp|Q636B6|MURG1_BACCZ
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A4J2B1 9.33e-90 1 354 1 351
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=murG PE=3 SV=1
A3DE27 4.81e-89 1 370 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
Q812W5 1.68e-85 1 370 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1 OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) OX=226900 GN=murG1 PE=3 SV=1
Q81JG5 2.67e-84 1 370 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1 OS=Bacillus anthracis OX=1392 GN=murG1 PE=3 SV=1
Q636B6 2.67e-84 1 370 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1 OS=Bacillus cereus (strain ZK / E33L) OX=288681 GN=murG1 PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000063 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003171_00332.