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CAZyme Information: MGYG000003177_00118

You are here: Home > Sequence: MGYG000003177_00118

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Amulumruptor sp900539915
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; Amulumruptor; Amulumruptor sp900539915
CAZyme ID MGYG000003177_00118
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
368 MGYG000003177_2|CGC1 39984.12 8.4004
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003177 2162791 MAG United States North America
Gene Location Start: 10453;  End: 11559  Strand: +

Full Sequence      Download help

MKTDYHILIS  GGGTGGHIFP  ALAIANALKQ  RLPGASIQFV  GADNRMEMER  VPEAGYPIIG60
LPVAGFDRKR  LWRNVGVLLK  LWRSSRMAKK  IVRDFKPDVA  IGVGGYASGP  TLAAAQQAHV120
PTLLQEQNSY  AGVTNKLLAK  DADRICVAYE  GMERFFPADR  IVMTGNPVRK  ALFDCKLTPA180
EAREALGFPA  DEPLVVVVGG  SLGARSVNDA  TYEAMDAITA  TGANLLWQTG  KIYYDEFAEK240
TRGKAKVKTM  AFLPDMATVY  RAATFVISRA  GASTISELQL  LGVPAILIPS  ANVAEDHQRK300
NAMALVDRDA  AMMILDAEAS  QRLKEEAPAL  LNDPERRDTY  AANVRKMALP  EADERIADEV360
ITLLNREK368

Enzyme Prediction      help

No EC number prediction in MGYG000003177_00118.

CAZyme Signature Domains help

Created with Snap1836557392110128147165184202220239257276294312331349195352GT28
Family Start End Evalue family coverage
GT28 195 352 1.4e-45 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18365573921101281471651842022202392572762943123313496366murG6359GT28_MurG7366MurG7360murG7145Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 4.53e-143 6 366 3 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 2.41e-138 6 359 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 2.83e-109 7 366 3 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 7.36e-102 7 360 3 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 7.35e-37 7 145 1 137
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18365573921101281471651842022202392572762943123313492368QCD36825.1|GT287366QCD41887.1|GT287368ASB37665.1|GT287368ANU64241.1|GT287368QQR08394.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QCD36825.1 3.15e-152 2 368 3 370
QCD41887.1 5.50e-152 7 366 17 376
ASB37665.1 2.10e-149 7 368 3 366
ANU64241.1 2.10e-149 7 368 3 366
QQR08394.1 2.10e-149 7 368 3 366

PDB Hits      download full data without filtering help

Created with Snap183655739211012814716518420222023925727629431233134963583S2U_A73601F0K_A63587D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 6.70e-54 6 358 4 349
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.21e-49 7 360 9 350
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 3.42e-49 6 358 11 360
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573921101281471651842022202392572762943123313491366sp|A6L071|MURG_PHOV85367sp|A6LEU3|MURG_PARD87363sp|Q64ZM1|MURG_BACFR7363sp|Q5LIJ7|MURG_BACFN1367sp|Q8A258|MURG_BACTN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A6L071 3.83e-131 1 366 1 369
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) OX=435590 GN=murG PE=3 SV=1
A6LEU3 1.93e-129 5 367 4 368
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152) OX=435591 GN=murG PE=3 SV=1
Q64ZM1 1.65e-128 7 363 16 376
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=murG PE=3 SV=1
Q5LIJ7 1.65e-128 7 363 16 376
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=murG PE=3 SV=2
Q8A258 2.53e-128 1 367 1 371
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000043 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003177_00118.