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CAZyme Information: MGYG000003203_00032

You are here: Home > Sequence: MGYG000003203_00032

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Butyricimonas sp900759925
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Marinifilaceae; Butyricimonas; Butyricimonas sp900759925
CAZyme ID MGYG000003203_00032
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
368 MGYG000003203_7|CGC1 40360.57 10.0231
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003203 5334161 MAG United States North America
Gene Location Start: 2160;  End: 3266  Strand: +

Full Sequence      Download help

MKKVIISGGG  TGGHIFPALS  IANALKRLDP  DIDILFVGAE  GKMEMEKVPE  AGYRIVGLPV60
RGLQRKLTLS  NLKVAWNLWR  SLRKAKRLVK  EFKPDVVVGV  GGYASGPIGR  VAAKAGIPLV120
LQEQNSYAGV  TNKLLAKKAE  KICVAYEGME  RFFPKEKIIL  TGNPVRKDLL  NALGEREEGL180
VFYGLDPKKK  TVLVTGGSLG  AGSMNKAMVR  WLERVAGWKD  VQVIWQCGSY  YHKQLEAELK240
DRLPENIKFM  PFLKRMDLAY  ACADLVVARA  GAGTISELCL  LGKAVVLVPS  PNVAEDHQTK300
NAMALVNKQA  AVMVKDSDVV  EQLGDVMERL  LTNDNERKAL  SEHILTLAMK  DSDEVIAKQI360
LKSLKCKV368

Enzyme Prediction      help

No EC number prediction in MGYG000003203_00032.

CAZyme Signature Domains help

Created with Snap1836557392110128147165184202220239257276294312331349191351GT28
Family Start End Evalue family coverage
GT28 191 351 4.1e-49 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18365573921101281471651842022202392572762943123313491365murG3358GT28_MurG2365MurG2360murG4142Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 4.81e-145 1 365 1 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.66e-135 3 358 1 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 7.77e-106 2 365 1 356
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.19e-99 2 360 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 1.47e-41 4 142 1 137
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18365573921101281471651842022202392572762943123313491362AZS29019.1|GT281362QRO49032.1|GT281362SNV32311.1|GT281362ADY32387.1|GT283362CDS92680.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
AZS29019.1 3.01e-235 1 362 1 362
QRO49032.1 8.64e-235 1 362 1 362
SNV32311.1 2.12e-196 1 362 1 362
ADY32387.1 2.12e-196 1 362 1 362
CDS92680.1 3.19e-156 3 362 4 362

PDB Hits      download full data without filtering help

Created with Snap183655739211012814716518420222023925727629431233134933623S2U_A23427D1I_A23601F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 2.61e-53 3 362 4 353
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 7.74e-52 2 342 10 341
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 3.55e-48 2 360 7 350
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573921101281471651842022202392572762943123313493362sp|A6LEU3|MURG_PARD83362sp|Q5LIJ7|MURG_BACFN3362sp|Q64ZM1|MURG_BACFR3364sp|A5FIY3|MURG_FLAJ13362sp|Q8A258|MURG_BACTN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A6LEU3 3.05e-143 3 362 5 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152) OX=435591 GN=murG PE=3 SV=1
Q5LIJ7 2.15e-141 3 362 15 375
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=murG PE=3 SV=2
Q64ZM1 2.15e-141 3 362 15 375
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=murG PE=3 SV=1
A5FIY3 4.24e-139 3 364 5 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 / UW101) OX=376686 GN=murG PE=3 SV=1
Q8A258 1.17e-136 3 362 6 366
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000057 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003203_00032.