logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000003303_00104

You are here: Home > Sequence: MGYG000003303_00104

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Senegalimassilia sp900550055
Lineage Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Eggerthellaceae; Senegalimassilia; Senegalimassilia sp900550055
CAZyme ID MGYG000003303_00104
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
369 MGYG000003303_14|CGC1 39165.96 7.8076
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003303 2430566 MAG China Asia
Gene Location Start: 3077;  End: 4186  Strand: +

Full Sequence      Download help

MRIVLSGGGT  AGHINPALAL  ADVLRERGHE  VLFAGTPGGI  ESRLVPAAGI  PYQAFEAAGF60
NRNHPLTLPK  AIMKIQRSTK  LARKWFTEVH  PDCVVGFGGY  VCIPVARAAE  QRGIPVVVHE120
QNSVMGMANK  YLARQARAVC  LTYEHAAQAL  SDKSKVVLTG  NPVRASVFAA  TRAEGRAAFG180
VPEDARMLLV  TGGSLGARHL  NAAIVQRKDM  LLSYPDLHIV  HVTGPKELDS  VAEQLSLTDA240
QAKRWHLMGY  TDQMGLAMAA  ADAIVSRAGA  TSLAEISARH  IPALLVPFPY  ATEDHQTMNA300
RACVEAGAAF  LVADADVEGG  QFTDYLKTLI  EDEGARQRMS  DAAAAAKTRD  AAGLLADVVL360
KACESKSAQ369

Enzyme Prediction      help

No EC number prediction in MGYG000003303_00104.

CAZyme Signature Domains help

Created with Snap1836557392110129147166184202221239258276295313332350187351GT28
Family Start End Evalue family coverage
GT28 187 351 9.7e-48 0.9936305732484076

CDD Domains      download full data without filtering help

Created with Snap18365573921101291471661842022212392582762953133323501362murG2358GT28_MurG1361MurG1341murG2329PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 5.52e-127 1 362 2 354
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 4.57e-121 2 358 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.30e-97 1 361 1 353
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.39e-89 1 341 1 330
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 6.76e-47 2 329 3 322
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18365573921101291471661842022212392582762953133323501366BAK44146.1|GT281366ACV56058.1|GT281366QOS67217.1|GT281368QTU84759.1|GT281367AJC12321.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
BAK44146.1 1.00e-195 1 366 1 366
ACV56058.1 1.85e-193 1 366 1 366
QOS67217.1 5.29e-193 1 366 1 366
QTU84759.1 1.97e-179 1 368 1 368
AJC12321.1 1.93e-159 1 367 1 367

PDB Hits      download full data without filtering help

Created with Snap183655739211012914716618420222123925827629531333235023613S2U_A23097D1I_A23121F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 3.49e-54 2 361 4 353
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 3.73e-48 2 309 11 313
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 1.96e-39 2 312 8 305
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573921101291471661842022212392582762953133323501340sp|B8CWJ6|MURG_HALOH1345sp|Q9K9T0|MURG_ALKHC1362sp|Q03W35|MURG_LEUMM1366sp|B1MXW0|MURG_LEUCK1342sp|A5D145|MURG_PELTS
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B8CWJ6 3.47e-77 1 340 1 345
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=murG PE=3 SV=1
Q9K9T0 5.30e-71 1 345 1 344
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) OX=272558 GN=murG PE=3 SV=1
Q03W35 5.30e-71 1 362 1 360
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) OX=203120 GN=murG PE=3 SV=1
B1MXW0 8.86e-71 1 366 1 367
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Leuconostoc citreum (strain KM20) OX=349519 GN=murG PE=3 SV=1
A5D145 2.95e-70 1 342 1 347
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) OX=370438 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000061 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003303_00104.