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CAZyme Information: MGYG000003409_00010

You are here: Home > Sequence: MGYG000003409_00010

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-110 sp900544945
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; CAG-110; CAG-110 sp900544945
CAZyme ID MGYG000003409_00010
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
373 MGYG000003409_3|CGC1 40411.55 7.5983
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003409 2672842 MAG Fiji Oceania
Gene Location Start: 5712;  End: 6833  Strand: +

Full Sequence      Download help

MNLIFTCGGT  AGHINPAIAV  ANAMREKYPD  CKILFIGAEG  HMEERLVPQA  GYEVRCLPGS60
GLSRKLNAAG  LKQNLHAVKC  VLGAVGECKR  IFRDFQPDAV  IGTGGYASFP  ALYAAQSMKI120
PTCVHESNAV  PGVTTKMAAS  RATRVLVAFE  ESVKHYKHPE  KVEVVGMPVR  KEFLFTTKEQ180
ARKALGVTEP  LVVSAFGSQG  AKVMNETVAD  MMVLEQADGF  PFHHIHATGS  FGKEWMPKRV240
KDNGVDYENC  PAIDIREYIY  DMPTVLTAAD  VVIGRAGSAT  CNEIAASGTP  CILVPSPNVT300
NNHQEKNARV  LESGGGAVVL  LEKDCTAETL  YGLIRQLLAD  ETRRAQMSRK  LHAQLRPDST360
DRICAIVEEI  TGR373

Enzyme Prediction      help

No EC number prediction in MGYG000003409_00010.

CAZyme Signature Domains help

Created with Snap1837557493111130149167186205223242261279298317335354196358GT28
Family Start End Evalue family coverage
GT28 196 358 7.1e-42 0.9554140127388535

CDD Domains      download full data without filtering help

Created with Snap18375574931111301491671862052232422612792983173353541373murG3366GT28_MurG1370MurG1367murG3147Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 2.38e-130 1 373 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 2.49e-125 3 366 2 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 8.84e-99 1 370 1 354
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 3.81e-93 1 367 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 2.50e-36 3 147 1 139
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18375574931111301491671862052232422612792983173353543370QCI58785.1|GT281370QUO35758.1|GT283370BCK83092.1|GT281363BCK80743.1|GT283370QUO37394.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QCI58785.1 3.99e-124 3 370 8 376
QUO35758.1 1.51e-122 1 370 1 370
BCK83092.1 6.03e-121 3 370 8 376
BCK80743.1 6.50e-119 1 363 1 363
QUO37394.1 8.40e-116 3 370 8 376

PDB Hits      download full data without filtering help

Created with Snap183755749311113014916718620522324226127929831733535433701F0K_A23707D1I_A23603S2U_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 2.53e-44 3 370 9 353
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 1.16e-38 2 370 11 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 8.44e-38 2 360 4 344
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574931111301491671862052232422612792983173353541370sp|A3DE27|MURG_ACET21371sp|Q8R9G6|MURG_CALS41371sp|B0K8K7|MURG_THEP31371sp|B0K3H0|MURG_THEPX1370sp|B8I6H3|MURG_RUMCH
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DE27 1.26e-92 1 370 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
Q8R9G6 1.02e-81 1 371 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1
B0K8K7 1.14e-80 1 371 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B0K3H0 1.14e-80 1 371 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
B8I6H3 8.07e-78 1 370 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000066 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003409_00010.