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CAZyme Information: MGYG000003710_00371

You are here: Home > Sequence: MGYG000003710_00371

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Loigolactobacillus coryniformis
Lineage Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; Loigolactobacillus; Loigolactobacillus coryniformis
CAZyme ID MGYG000003710_00371
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
363 MGYG000003710_21|CGC1 39865.06 9.6096
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003710 2331695 MAG Russia Europe
Gene Location Start: 2507;  End: 3598  Strand: +

Full Sequence      Download help

MRVIFSGGGT  GGHIYPALAV  LERLKERDLL  DEVLYIGTEK  GLESRIIRQK  QIPFEAIELQ60
GFKRSLSLEN  LKTIKLFLQS  TRRAKQILRD  FKPDVVVGTG  GYVSSAVLFA  AARLHIPTVI120
NEQNSVAGIT  NRFLGRYVDR  ISIAFPEVAE  QFPKAKVVLT  GNPRAQQVAG  IQPNQRLTDF180
KLQPTIPTLL  IFGGSRGAER  INAAFLEALP  ELNQKDYQVL  FVSGRVHYAK  IQKALAEQTV240
AANVAVVPYI  NDMQTVLPDI  AVILGRAGAT  SLAEITALGI  PSILVPSPYV  TNDHQTKNAQ300
SLVSHQAAEM  ITENELTGTS  LLKVTDHLMQ  DQSLRQAMGE  QARQLGVPDA  ADRFIKVMQD360
LIH363

Enzyme Prediction      help

No EC number prediction in MGYG000003710_00371.

CAZyme Signature Domains help

Created with Snap1836547290108127145163181199217235254272290308326344188350GT28
Family Start End Evalue family coverage
GT28 188 350 6.7e-49 0.9936305732484076

CDD Domains      download full data without filtering help

Created with Snap18365472901081271451631811992172352542722903083263441363murG2357GT28_MurG1362MurG1357murG3143Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 6.64e-151 1 363 2 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 2.69e-143 2 357 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 3.38e-117 1 362 1 355
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.52e-114 1 357 1 347
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 9.34e-49 3 143 1 139
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18365472901081271451631811992172352542722903083263441363QEA54043.1|GT281363ATO55255.1|GT281363ATO43575.1|GT281361SFZ87879.1|GT281362ANK66814.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QEA54043.1 1.56e-256 1 363 1 363
ATO55255.1 6.36e-256 1 363 1 363
ATO43575.1 3.68e-255 1 363 1 363
SFZ87879.1 8.62e-204 1 361 1 361
ANK66814.1 2.62e-197 1 362 1 361

PDB Hits      download full data without filtering help

Created with Snap183654729010812714516318119921723525427229030832634423617D1I_A23633S2U_A23531F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 2.10e-54 2 361 11 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 3.43e-52 2 363 4 360
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.10e-42 2 353 8 345
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365472901081271451631811992172352542722903083263444362sp|Q38XM8|MURG_LATSS1362sp|Q88V81|MURG_LACPL1363sp|Q1WTA0|MURG_LIGS11361sp|Q03QH5|MURG_LEVBA1362sp|Q039R7|MURG_LACP3
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q38XM8 4.44e-162 4 362 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Latilactobacillus sakei subsp. sakei (strain 23K) OX=314315 GN=murG PE=3 SV=1
Q88V81 3.42e-159 1 362 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) OX=220668 GN=murG PE=3 SV=1
Q1WTA0 1.63e-155 1 363 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Ligilactobacillus salivarius (strain UCC118) OX=362948 GN=murG PE=3 SV=1
Q03QH5 1.07e-148 1 361 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Levilactobacillus brevis (strain ATCC 367 / BCRC 12310 / CIP 105137 / JCM 1170 / LMG 11437 / NCIMB 947 / NCTC 947) OX=387344 GN=murG PE=3 SV=1
Q039R7 1.96e-146 1 362 1 359
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441) OX=321967 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000080 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003710_00371.