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CAZyme Information: MGYG000003729_00288

You are here: Home > Sequence: MGYG000003729_00288

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Peptostreptococcus sp000758885
Lineage Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Peptostreptococcus; Peptostreptococcus sp000758885
CAZyme ID MGYG000003729_00288
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
365 MGYG000003729_9|CGC1 40314.52 6.6546
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003729 1511126 MAG Canada North America
Gene Location Start: 14955;  End: 16052  Strand: +

Full Sequence      Download help

MKVILSGGGT  GGHVYPAIAI  ANKIKEHNPD  AEILFVGTRA  GIESEIVPKY  GYDIEFIDVQ60
GFKRKIDLDN  VKRLLKFLKS  LGDSKKIIKK  FKPDLVIGTG  GYVSGSVVLK  ASKMGISSCI120
HEQNSFPGMT  NKMLSKNVDL  VMTSFEDSHK  RFPDQAKDKL  FFTGNPVRDD  ILKADKMESR180
RILGLTEDEK  MLLVAGGSGG  SEEINDALKK  VMPKLVEDRI  AFTIATGRAY  YDKFMKDYGY240
LKYGPNQKIL  PYLDDMANNL  AAADLVIGSA  GAISMAEMTA  IGVPAIIIPK  AYTAENHQEY300
NAKSLERAGG  AVCITEKELN  EDSLYENIFD  LLYDQDRLDD  MSKASKAFGK  RDAIELIYEC360
ISKFL365

Enzyme Prediction      help

No EC number prediction in MGYG000003729_00288.

CAZyme Signature Domains help

Created with Snap1836547391109127146164182200219237255273292310328346191353GT28
Family Start End Evalue family coverage
GT28 191 353 4.5e-47 0.9936305732484076

CDD Domains      download full data without filtering help

Created with Snap18365473911091271461641822002192372552732923103283462359GT28_MurG1365murG1359MurG1361murG2363PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03785 GT28_MurG 6.22e-148 2 359 1 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
PRK00726 murG 8.25e-147 1 365 2 355
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
COG0707 MurG 2.32e-117 1 359 1 349
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 3.39e-109 1 361 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 2.32e-46 2 363 3 351
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18365473911091271461641822002192372552732923103283461363CEI73801.1|GT281363ALP03736.1|GT281363CDT63800.1|GT281365QEK20347.1|GT281363QQY77001.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
CEI73801.1 3.57e-158 1 363 1 363
ALP03736.1 3.14e-157 1 363 1 363
CDT63800.1 3.14e-157 1 363 1 363
QEK20347.1 4.78e-157 1 365 1 365
QQY77001.1 5.10e-157 1 363 1 363

PDB Hits      download full data without filtering help

Created with Snap183654739110912714616418220021923725527329231032834623593S2U_A23631F0K_A33637D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 1.50e-50 2 359 4 349
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 2.20e-49 2 363 8 352
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 3.35e-41 3 363 12 364
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365473911091271461641822002192372552732923103283461363sp|Q182Y6|MURG_CLOD61365sp|A3DE27|MURG_ACET21358sp|A6TS61|MURG_ALKMQ1358sp|A8MH36|MURG_ALKOO1365sp|Q812W5|MURG1_BACCR
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q182Y6 1.50e-157 1 363 2 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridioides difficile (strain 630) OX=272563 GN=murG PE=3 SV=1
A3DE27 4.33e-115 1 365 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
A6TS61 3.27e-106 1 358 1 357
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus metalliredigens (strain QYMF) OX=293826 GN=murG PE=3 SV=1
A8MH36 4.63e-106 1 358 1 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus oremlandii (strain OhILAs) OX=350688 GN=murG PE=3 SV=1
Q812W5 2.37e-100 1 365 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1 OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) OX=226900 GN=murG1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000070 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003729_00288.