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CAZyme Information: MGYG000003808_00138

You are here: Home > Sequence: MGYG000003808_00138

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Pauljensenia culturomici
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Actinomycetaceae; Pauljensenia; Pauljensenia culturomici
CAZyme ID MGYG000003808_00138
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
371 MGYG000003808_3|CGC1 38719.34 6.2506
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003808 2368539 MAG Canada North America
Gene Location Start: 35799;  End: 36914  Strand: +

Full Sequence      Download help

MTRRIVVAGG  GTAGHVNPLL  STAVELRRRG  VDVDVLGTKE  GLEADLVPAA  GFALSVIDKV60
PFPRRPTPSA  LAFPRKWRRA  VVACEDVVRG  ADCVVGFGGY  VSTPAYRAAK  RLGVPIVIHE120
QNARPGLANR  VGARTAALVA  LTFTNTPLTA  ARGRTEVTGL  PLRPAIADLA  RKRQDPASRR180
TAREEAAARL  GVDPDAPTLL  VTGGSLGALH  LNEAMTAAAT  RLPEEARVVH  LTGRGKDAPV240
REAIETAGLT  DRWLVLDYLT  TMEDALAVAD  LVVCRSGAGT  VAEMTALGLP  CVYVPLPIGN300
GEQRLNAHDH  VAAGGALLVD  DADLDADYVA  GTVFPLLGST  DLETMAAASA  GLGRVDAASD360
FCDLIETVID  K371

Enzyme Prediction      help

No EC number prediction in MGYG000003808_00138.

CAZyme Signature Domains help

Created with Snap1837557492111129148166185204222241259278296315333352198356GT28
Family Start End Evalue family coverage
GT28 198 356 1.5e-43 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18375574921111291481661852042222412592782963153333523371murG4364GT28_MurG3369MurG3365murG5140Glyco_transf_28
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 2.51e-117 3 371 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.25e-102 4 364 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 2.98e-89 3 369 1 355
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.73e-81 3 365 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam03033 Glyco_transf_28 1.08e-36 5 140 1 138
Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.

CAZyme Hits      help

Created with Snap18375574921111291481661852042222412592782963153333524364QCT35695.1|GT281371QYB15888.1|GT284364QGS10808.1|GT287365AOS47979.1|GT284364QQC44616.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QCT35695.1 7.18e-172 4 364 3 363
QYB15888.1 2.62e-171 1 371 1 371
QGS10808.1 4.13e-171 4 364 3 363
AOS47979.1 2.49e-168 7 365 1 359
QQC44616.1 2.61e-167 4 364 3 363

PDB Hits      download full data without filtering help

Created with Snap183755749211112914816618520422224125927829631533335233681F0K_A13633S2U_A33667D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 6.59e-44 3 368 7 353
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
3S2U_A 3.87e-41 1 363 1 349
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 4.22e-37 3 366 10 363
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574921111291481661852042222412592782963153333523371sp|A1A2E9|MURG_BIFAA2329sp|B3DQN1|MURG_BIFLD2329sp|Q8CY50|MURG_BIFLO2329sp|B7GQ78|MURG_BIFLS6369sp|A5CS51|MURG_CLAM3
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A1A2E9 5.44e-105 3 371 5 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) OX=367928 GN=murG PE=3 SV=1
B3DQN1 2.57e-100 2 329 5 348
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum (strain DJO10A) OX=205913 GN=murG PE=3 SV=1
Q8CY50 2.57e-100 2 329 5 348
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum (strain NCC 2705) OX=206672 GN=murG PE=3 SV=1
B7GQ78 2.57e-100 2 329 5 348
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) OX=391904 GN=murG PE=3 SV=1
A5CS51 4.71e-97 6 369 5 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) OX=443906 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000057 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003808_00138.