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CAZyme Information: MGYG000003857_00101

You are here: Home > Sequence: MGYG000003857_00101

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Cyanobacteria; Vampirovibrionia; Gastranaerophilales; Gastranaerophilaceae; RUG841;
CAZyme ID MGYG000003857_00101
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
372 MGYG000003857_4|CGC1 41504.74 9.8236
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003857 1817818 MAG United States North America
Gene Location Start: 8068;  End: 9186  Strand: +

Full Sequence      Download help

MSKKNVYFIS  GGGTGGHIYP  ALSVVQELLK  REDTAKIYYI  GNPKNMEYDI  VKKIANVEFL60
PISVMGMPRK  LSFGLVKFFV  MLAVAVIKAI  LYVKKYKPDA  VFTTGGYVSA  PIALVAPFMN120
VPLMIHDCDA  IPGLVSKLVA  PRAKVVSVAF  ESSKNFLKNK  NIICTGNPVR  SEFLTVTKEQ180
AREKLGLRNK  MTVFLTGGSQ  GAKTLNKTAI  KAAQTMVEEL  DVQFVIQTGK  KKYDDFIKEI240
SAYFPNYSQN  TNLVIRPYFD  EMYYALKAAD  IVIARAGSLS  LSELTLCGSA  CILVPYPYAA300
ADHQRKNARE  AEKMGFALYC  EDKDFERERM  LELVKSLVNN  PDYVKKMSKA  AYMNSRPQAK360
QEIIENLISI  IK372

Enzyme Prediction      help

No EC number prediction in MGYG000003857_00101.

CAZyme Signature Domains help

Created with Snap1837557493111130148167186204223241260279297316334353192358GT28
Family Start End Evalue family coverage
GT28 192 358 6.9e-46 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343533372murG8366GT28_MurG8372MurG9365murG4371PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 2.66e-120 3 372 1 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.87e-112 8 366 3 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 3.65e-97 8 372 4 356
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.68e-87 9 365 5 346
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 1.36e-39 4 371 2 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18375574931111301481671862042232412602792973163343537370AOR38118.1|GT287365AAM24847.1|GT289371ABO49214.1|GT281372ADQ04199.1|GT287372AEM79007.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
AOR38118.1 4.78e-120 7 370 4 362
AAM24847.1 1.74e-75 7 365 3 358
ABO49214.1 4.37e-75 9 371 5 368
ADQ04199.1 7.99e-75 1 372 1 369
AEM79007.1 9.75e-75 7 372 3 361

PDB Hits      download full data without filtering help

Created with Snap183755749311113014816718620422324126027929731633435313657D1I_A33723S2U_A93171F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 4.50e-46 1 365 6 360
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 1.04e-41 3 372 2 356
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.53e-31 9 317 11 302
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343537365sp|Q8R9G6|MURG_CALS49371sp|A4J2B1|MURG_DESRM7370sp|B0K8K7|MURG_THEP37370sp|B0K3H0|MURG_THEPX9364sp|Q24TE6|MURG_DESHY
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8R9G6 3.48e-76 7 365 3 358
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=murG PE=3 SV=1
A4J2B1 8.75e-76 9 371 5 368
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=murG PE=3 SV=1
B0K8K7 3.07e-74 7 370 3 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B0K3H0 3.07e-74 7 370 3 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
Q24TE6 2.46e-71 9 364 5 360
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfitobacterium hafniense (strain Y51) OX=138119 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000034 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
7 29
71 93
100 122