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CAZyme Information: MGYG000003922_00448

You are here: Home > Sequence: MGYG000003922_00448

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides sp014385165
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides sp014385165
CAZyme ID MGYG000003922_00448
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
374 MGYG000003922_3|CGC2 40676.62 10.2383
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003922 4876803 MAG China Asia
Gene Location Start: 66554;  End: 67678  Strand: -

Full Sequence      Download help

MEKELRIIIS  GGGTGGHIFP  AVSIANAIKE  LRPDARILFV  GAEGRMEMQR  VPDAGYEIIG60
LPVAGFDRKH  LWKNFAVLIK  LARSQWKAKS  IIKKFRPQVA  VGVGGYASGP  TLKMAGMMGI120
PTLIQEQNSY  AGVTNKLLAK  KAQRICVAYD  GMEKFFPKEK  IQMTGNPVRQ  NLLTATRDHE180
SAITSFGLDP  KKKTILILGG  SLGARTINNT  LKAGLQTIKE  TPAIQFIWQT  GKIYHQQVME240
AVKAAGNIPN  LYVTDFIKDM  ATAYSAADLV  ISRAGAGSIS  EFCLLHKPVI  LIPSPNVAED300
HQTKNALALV  NKQAAIYVKD  VEAEEKLLPV  ALATVIDTGK  LKELSDNIAK  LALPDSATII360
AREVIKLGER  RNDK374

Enzyme Prediction      help

No EC number prediction in MGYG000003922_00448.

CAZyme Signature Domains help

Created with Snap1837567493112130149168187205224243261280299317336355194355GT28
Family Start End Evalue family coverage
GT28 194 355 6.8e-46 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap183756749311213014916818720522424326128029931733635519370murG19363GT28_MurG19367MurG19361murG194357Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 2.79e-133 19 370 16 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.66e-120 19 363 14 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 6.65e-89 19 367 15 354
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 7.43e-87 19 361 15 345
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam04101 Glyco_tran_28_C 1.79e-34 194 357 1 163
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap18375674931121301491681872052242432612802993173363551373QUT74043.1|GT282370QCQ35447.1|GT282370AUI49317.1|GT282370QCQ31031.1|GT282370QRM69348.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QUT74043.1 6.63e-229 1 373 1 373
QCQ35447.1 3.88e-225 2 370 11 379
AUI49317.1 3.88e-225 2 370 11 379
QCQ31031.1 3.88e-225 2 370 11 379
QRM69348.1 3.88e-225 2 370 11 379

PDB Hits      download full data without filtering help

Created with Snap183756749311213014916818720522424326128029931733635563681F0K_A63683S2U_A23677D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 5.81e-48 6 368 8 354
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
3S2U_A 1.64e-47 6 368 4 355
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 5.19e-44 2 367 7 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375674931121301491681872052242432612802993173363555370sp|Q5LIJ7|MURG_BACFN5370sp|Q64ZM1|MURG_BACFR1372sp|Q8A258|MURG_BACTN1370sp|A6L071|MURG_PHOV83371sp|A6LEU3|MURG_PARD8
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q5LIJ7 1.43e-221 5 370 14 379
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=murG PE=3 SV=2
Q64ZM1 1.43e-221 5 370 14 379
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=murG PE=3 SV=1
Q8A258 1.95e-217 1 372 1 372
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=murG PE=3 SV=1
A6L071 1.19e-184 1 370 1 369
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) OX=435590 GN=murG PE=3 SV=1
A6LEU3 1.61e-149 3 371 2 368
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152) OX=435591 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000078 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003922_00448.