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CAZyme Information: MGYG000004138_00858

You are here: Home > Sequence: MGYG000004138_00858

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species QAMH01 sp900544245
Lineage Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; QAMH01; QAMH01; QAMH01 sp900544245
CAZyme ID MGYG000004138_00858
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
369 MGYG000004138_1|CGC4 38946.28 5.37
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004138 1946641 MAG United Kingdom Europe
Gene Location Start: 994331;  End: 995440  Strand: -

Full Sequence      Download help

MYFVISAGGT  AGHINPALAV  ADELRRRGHD  ILFVGTPDHI  ESRLAAQAGF  EFESFAVSGF60
DKAHPLTLLT  SGAKLLKATR  AARRLFAARR  PDAVVTFGAY  VSIPVGRAAF  EMNIPLVIHE120
QNSVPGMANA  YLAKHATAIA  LTYPESAEGL  DGACDPVVLG  NPVRASFEAC  SRHEARKALG180
MPDDALVLLV  MGGSLGAQHV  NTAICAMKDR  LLAIEGLHVI  QSTGQGDYER  VLGQLALSAD240
EEGRWHVSSY  IDSMNEVLAA  SDLVVSRAGA  SSLAEIMTVG  VPAVLIPYPH  ARGDHQTINA300
QSCVTAGAAR  LVSDADVETT  AFSDLLIELL  GDEGCRDTMA  QACKKLSGSD  ARMRLADLVE360
QCARGNDGE369

Enzyme Prediction      help

No EC number prediction in MGYG000004138_00858.

CAZyme Signature Domains help

Created with Snap1836557392110129147166184202221239258276295313332350188350GT28
Family Start End Evalue family coverage
GT28 188 350 3.8e-47 0.9808917197452229

CDD Domains      download full data without filtering help

Created with Snap18365573921101291471661842022212392582762953133323501365murG3358GT28_MurG1365MurG1359murG4361PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 9.64e-120 1 365 2 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 3.03e-116 3 358 2 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.71e-99 1 365 1 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 2.32e-92 1 359 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
PRK12446 PRK12446 1.48e-42 4 361 5 351
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap18365573921101291471661842022212392582762953133323501364QTU84759.1|GT281363AJC12321.1|GT281363QKF07923.1|GT281364QOS67217.1|GT281363ACU94645.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QTU84759.1 4.47e-130 1 364 1 364
AJC12321.1 9.24e-126 1 363 1 363
QKF07923.1 2.38e-122 1 363 1 363
QOS67217.1 1.80e-121 1 364 1 364
ACU94645.1 9.96e-121 1 363 1 363

PDB Hits      download full data without filtering help

Created with Snap183655739211012914716618420222123925827629531333235043653S2U_A43641F0K_A23617D1I_A1582884WYI_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 1.36e-48 4 365 6 357
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.86e-48 4 364 10 355
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 1.60e-45 2 361 11 364
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
4WYI_A 1.37e-07 158 288 182 315
Thecrystal structure of Arabidopsis thaliana galactolipid synthase, MGD1 (apo-form) [Arabidopsis thaliana],4X1T_A The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP [Arabidopsis thaliana]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573921101291471661842022212392582762953133323501366sp|B8CWJ6|MURG_HALOH2356sp|Q2S528|MURG_SALRD1358sp|Q24TE6|MURG_DESHY1360sp|A3DE27|MURG_ACET21364sp|A5D145|MURG_PELTS
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B8CWJ6 2.13e-72 1 366 1 371
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=murG PE=3 SV=1
Q2S528 3.00e-65 2 356 7 357
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Salinibacter ruber (strain DSM 13855 / M31) OX=309807 GN=murG PE=3 SV=1
Q24TE6 1.15e-64 1 358 1 362
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulfitobacterium hafniense (strain Y51) OX=138119 GN=murG PE=3 SV=1
A3DE27 1.15e-64 1 360 1 360
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
A5D145 4.16e-63 1 364 1 369
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) OX=370438 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000059 0.000002 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004138_00858.