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CAZyme Information: MGYG000004232_00086

You are here: Home > Sequence: MGYG000004232_00086

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Terrisporobacter sp900557165
Lineage Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Terrisporobacter; Terrisporobacter sp900557165
CAZyme ID MGYG000004232_00086
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
404 MGYG000004232_2|CGC1 44666.9 9.7279
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004232 2591540 MAG United Kingdom Europe
Gene Location Start: 42380;  End: 43594  Strand: -

Full Sequence      Download help

MKVLLSGGGT  GGHVYPAIAI  ANKIKEENPD  CEILFVGTEK  GIESEIVPKY  GYELKTVTVQ60
GFRRKIDFEN  VKRVFKLCKG  LEQSRRIVKK  YKPDIVIGTG  GYVSGPVLFN  SALNKNVTIV120
HEQNSFPGVT  NKILSKVVTK  VLTSFEDSHK  RFPEESQSKL  VLTGNPVRKE  ILQARKSVSR180
KKLGISEDKK  MVLCYGGSGG  SEEINEAMLL  VIKNMVREDV  AFIFATGKLY  YNDFIKALGD240
IPLKPYQRVM  PYLDNMADGL  AASDIVIGSA  GAISLAEITA  LGKPSIIIPK  AYTAENHQEY300
NAKSIESQGA  GIAILEKDLT  PERLNEVVFK  LLGDKELLMD  MANASKSIGK  PQAIDLIYDE360
IMKAYNEKQA  FKNNKKEKQV  KKIEKSQEAD  EATKEVKTIG  IKKK404

Enzyme Prediction      help

No EC number prediction in MGYG000004232_00086.

CAZyme Signature Domains help

Created with Snap20406080101121141161181202222242262282303323343363383192353GT28
Family Start End Evalue family coverage
GT28 192 353 1.9e-42 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap204060801011211411611812022222422622823033233433633832360GT28_MurG1364murG1361murG1361MurG2336PRK12446
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03785 GT28_MurG 5.36e-147 2 360 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
PRK00726 murG 2.52e-146 1 364 2 354
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
TIGR01133 murG 2.51e-110 1 361 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0707 MurG 5.72e-110 1 361 1 351
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
PRK12446 PRK12446 6.89e-51 2 336 3 327
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed

CAZyme Hits      help

Created with Snap204060801011211411611812022222422622823033233433633831377QJA09280.1|GT281404QYE97566.1|GT281404CEJ74863.1|GT281404AUN15465.1|GT281404CEK39311.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QJA09280.1 1.21e-221 1 377 1 377
QYE97566.1 3.49e-218 1 404 1 401
CEJ74863.1 4.96e-218 1 404 1 401
AUN15465.1 4.96e-218 1 404 1 401
CEK39311.1 9.99e-218 1 404 1 401

PDB Hits      download full data without filtering help

Created with Snap2040608010112114116118120222224226228230332334336338323593S2U_A33637D1I_A23611F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 3.12e-49 2 359 4 349
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 4.82e-47 3 363 12 364
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 9.21e-47 2 361 8 350
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap204060801011211411611812022222422622823033233433633831375sp|Q182Y6|MURG_CLOD61370sp|A3DE27|MURG_ACET21362sp|A6TS61|MURG_ALKMQ1368sp|A8MH36|MURG_ALKOO1358sp|B0K8K7|MURG_THEP3
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q182Y6 1.22e-216 1 375 2 376
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridioides difficile (strain 630) OX=272563 GN=murG PE=3 SV=1
A3DE27 4.03e-118 1 370 1 368
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
A6TS61 6.23e-114 1 362 1 361
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus metalliredigens (strain QYMF) OX=293826 GN=murG PE=3 SV=1
A8MH36 1.94e-107 1 368 1 366
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Alkaliphilus oremlandii (strain OhILAs) OX=350688 GN=murG PE=3 SV=1
B0K8K7 2.07e-106 1 358 1 357
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000073 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004232_00086.