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CAZyme Information: MGYG000004691_00003

You are here: Home > Sequence: MGYG000004691_00003

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA9502 sp900555625
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UBA9502; UBA9502 sp900555625
CAZyme ID MGYG000004691_00003
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
360 MGYG000004691_1|CGC1 39368.63 9.0129
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004691 2701187 MAG China Asia
Gene Location Start: 2292;  End: 3374  Strand: +

Full Sequence      Download help

MKKIILTGGG  TAGHVTPNLA  LLPSLKERGY  EIHYIGTYNG  IERKLVEGAG  IPYDGISSGK60
LRRYFDLKNF  SDPFRVIKGY  MEARSLMKKY  KPDVVFSKGG  FVAVPVVLAA  KHFKIPTIIH120
ESDMTPGLAN  KICIPSAAKV  CCNFPETLQY  LPKEKAVLTG  SPIRRELLEG  DRLTGLQYAG180
LSADKPVILV  IGGSLGAVAV  NNAVRSLLPR  LLPHFQIIHI  CGKGHLDESL  IGQTGYVQYE240
YVDAPLRHLF  ACADLMLSRA  GANSICEILA  LRKPNVLIPL  SAAASRGDQI  LNARSFEKQG300
FSTVLEEETV  TDDTLFDAID  RTYRDRQKFI  DAMSKSAHSD  AVTTIVGLIE  SYAEKSTQKS360
360

Enzyme Prediction      help

No EC number prediction in MGYG000004691_00003.

CAZyme Signature Domains help

Created with Snap1836547290108126144162180198216234252270288306324342188338GT28
Family Start End Evalue family coverage
GT28 188 338 7.1e-39 0.9426751592356688

CDD Domains      download full data without filtering help

Created with Snap18365472901081261441621801982162342522702883063243421349PRK124461355murG3349GT28_MurG2355MurG2349murG
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK12446 PRK12446 2.61e-153 1 349 1 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed
PRK00726 murG 6.33e-151 1 355 1 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.05e-129 3 349 1 347
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.19e-117 2 355 1 357
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 4.36e-99 2 349 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits      help

Created with Snap18365472901081261441621801982162342522702883063243421354QJU22181.1|GT281349CBK75920.1|GT281351ASN93466.1|GT281351QRP41875.1|GT281351QQQ98361.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QJU22181.1 2.66e-206 1 354 1 354
CBK75920.1 3.78e-206 1 349 1 349
ASN93466.1 5.37e-206 1 351 1 351
QRP41875.1 5.37e-206 1 351 1 351
QQQ98361.1 5.37e-206 1 351 1 351

PDB Hits      download full data without filtering help

Created with Snap183654729010812614416218019821623425227028830632434223507D1I_A23151F0K_A33093S2U_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 3.83e-43 2 350 10 363
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 1.54e-40 2 315 7 315
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
3S2U_A 3.16e-39 3 309 4 308
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365472901081261441621801982162342522702883063243421350sp|A9KK83|MURG_LACP71350sp|C4Z1B5|MURG_LACE21354sp|C3L230|MURG_CLOB61354sp|B1KYH7|MURG_CLOBM3352sp|A0Q182|MURG_CLONN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A9KK83 2.27e-178 1 350 1 350
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) OX=357809 GN=murG PE=3 SV=1
C4Z1B5 1.85e-165 1 350 1 350
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4) OX=515620 GN=murG PE=3 SV=1
C3L230 1.93e-148 1 354 1 354
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain 657 / Type Ba4) OX=515621 GN=murG PE=3 SV=1
B1KYH7 1.93e-148 1 354 1 354
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Loch Maree / Type A3) OX=498214 GN=murG PE=3 SV=1
A0Q182 4.31e-148 3 352 5 355
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium novyi (strain NT) OX=386415 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000035 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004691_00003.