logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000002113_00275

You are here: Home > Sequence: MGYG000002113_00275

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Anaerovibrio sp900548165
Lineage Bacteria; Firmicutes_C; Negativicutes; Selenomonadales; Selenomonadaceae; Anaerovibrio; Anaerovibrio sp900548165
CAZyme ID MGYG000002113_00275
CAZy Family GT30
CAZyme Description Tetraacyldisaccharide 4'-kinase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
827 MGYG000002113_9|CGC2 92383.97 8.0749
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002113 1986108 MAG Mongolia Asia
Gene Location Start: 9331;  End: 11814  Strand: +

Full Sequence      Download help

MRLLYNVAAV  LVVILMIPAF  CLRAIREKGF  VNRIKQQLGF  LPKHALDKVA  RKNCIWVHAA60
SVGEIVAASP  LIKEFRREFP  NTPILVSVFT  NSGYEMANRI  IKDADSIIHF  PFDLPWLSAH120
LLYKVRPRVF  MPVETELWPN  FLQAAKKLDI  PVMMVNGRIS  EKSVSRYRYL  HSIWYDMLDT180
IKYFAMQSSV  DAENILRLGA  SKDLVTVTGN  TKFDQTYTNV  SPEEKQQLIK  ELGLEDNDGI240
FLAGSTHKGE  EEQVLAAFGE  IRKTHPKARL  VIAPRAVLRT  GTIQDMCQQG  GFTSATRTQL300
QEKPAQGHDV  VLLNTIGELG  KVYSIGDVIF  VGGSLIPHGG  HNILEPAAHG  KAIIVGPNMF360
NFKDTHILFS  NRKAVVTVQN  QEELIKAASE  LFVNVAERRR  MEQETLKICE  ENRGAARRTA420
VILHDLLNCC  EAKDKVKAID  KLENFQTYFM  QLIHCKEPKG  LGLKAMVAFL  HGCAYIYGFL480
LNIKLSCYKS  GLLTRKKLDC  YVISLGNITV  GGTGKTPTAQ  RLAKAIRDMG  YKVVILNRGY540
RAKWQGEIGV  VSDGHELKMD  AATAGDEAFM  LAKHLPNVPV  LIGPERAKTG  QYAVEHFGAQ600
VAILDDGYQH  WQLKRNLDVV  LIDAVNVFGN  GHILPRGTLR  EPLSHLSRAD  VCLLTKVDQA660
EPGSIAYIRK  KIDEYGKNPV  VVESIHQPQA  CIELGEWVKN  IASEGSPIDI  IKGKKIIALS720
AIGNPASFEQ  TLCNSGAEVI  ESFRFPDHHE  YTLEEIQDAM  DQAIREGAEA  IATTEKDAVK780
LPHLPEREGN  LPIYVITVEV  VMQDEGKQID  QLLKQRIDDF  FRRSEQK827

Enzyme Prediction      help

No EC number prediction in MGYG000002113_00275.

CAZyme Signature Domains help

Created with Snap418212416520624828933037241345449653757862066170274478533215GT30
Family Start End Evalue family coverage
GT30 33 215 1.8e-57 0.9830508474576272

CDD Domains      download full data without filtering help

Created with Snap41821241652062482893303724134544965375786206617027447851429PRK057491423KdtA474814LpxK476818lpxK474814LpxK
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK05749 PRK05749 7.66e-132 1 429 2 423
3-deoxy-D-manno-octulosonic-acid transferase; Reviewed
COG1519 KdtA 8.75e-121 1 423 1 415
3-deoxy-D-manno-octulosonic-acid transferase [Cell wall/membrane/envelope biogenesis].
pfam02606 LpxK 1.62e-90 474 814 9 318
Tetraacyldisaccharide-1-P 4'-kinase. This family consists of tetraacyldisaccharide-1-P 4'-kinase also known as Lipid-A 4'-kinase or Lipid A biosynthesis protein LpxK, EC:2.7.1.130. This enzyme catalyzes the reaction: ATP + 2,3-bis(3-hydroxytetradecanoyl)-D -glucosaminyl-(beta-D-1,6)-2,3-bis(3-hydroxytetradecanoyl)-D-glu cosam inyl beta-phosphate <=> ADP + 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D- glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate. This enzyme is involved in the synthesis of lipid A portion of the bacterial lipopolysaccharide layer (LPS). The family contains a P-loop motif at the N-terminus.
PRK00652 lpxK 1.25e-73 476 818 25 324
tetraacyldisaccharide 4'-kinase; Reviewed
COG1663 LpxK 1.82e-71 474 814 24 330
Tetraacyldisaccharide-1-P 4'-kinase [Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Created with Snap41821241652062482893303724134544965375786206617027447851813AEC00854.1|GT301818BAL84301.1|GT301817QIB60789.1|GT301817BDA10745.1|GT301817SNU94361.1|GT30
Hit ID E-Value Query Start Query End Hit Start Hit End
AEC00854.1 0.0 1 813 1 817
BAL84301.1 0.0 1 818 1 823
QIB60789.1 0.0 1 817 1 820
BDA10745.1 0.0 1 817 1 820
SNU94361.1 0.0 1 817 1 820

PDB Hits      download full data without filtering help

Created with Snap41821241652062482893303724134544965375786206617027447854748074EHX_A4748074EHW_A403922XCI_A2234274BFC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4EHX_A 6.71e-46 474 807 10 305
Crystalstructure of LpxK from Aquifex aeolicus at 1.9 angstrom resolution [Aquifex aeolicus VF5],4EHY_A Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution [Aquifex aeolicus VF5],4ITL_A Crystal structure of LpxK from Aquifex aeolicus in complex with AMP-PCP at 2.1 angstrom resolution [Aquifex aeolicus VF5],4ITM_A Crystal structure of 'apo' form LpxK from Aquifex aeolicus in complex with ATP at 2.2 angstrom resolution [Aquifex aeolicus VF5],4ITN_A Crystal structure of 'compact P-loop' LpxK from Aquifex aeolicus in complex with chloride at 2.2 angstrom resolution [Aquifex aeolicus VF5],4LKV_A Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5],4LKV_B Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5],4LKV_C Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5],4LKV_D Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5]
4EHW_A 7.07e-46 474 807 12 307
Crystalstructure of LpxK from Aquifex aeolicus at 2.3 angstrom resolution [Aquifex aeolicus VF5]
2XCI_A 3.95e-35 40 392 30 344
Membrane-embeddedmonofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCI_B Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCI_C Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCI_D Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCU_A Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus],2XCU_B Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus],2XCU_C Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus],2XCU_D Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus]
4BFC_A 5.38e-17 223 427 28 231
ChainA, 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap4182124165206248289330372413454496537578620661702744785443803sp|B8CZC3|LPXK_HALOH488805sp|A7HDI5|LPXK_ANADF442814sp|A5G6H1|LPXK_GEOUR488790sp|Q2IL55|LPXK_ANADE488781sp|B4UHQ4|LPXK_ANASK
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B8CZC3 1.78e-70 443 803 7 372
Tetraacyldisaccharide 4'-kinase OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=lpxK PE=3 SV=1
A7HDI5 1.17e-64 488 805 42 350
Tetraacyldisaccharide 4'-kinase OS=Anaeromyxobacter sp. (strain Fw109-5) OX=404589 GN=lpxK PE=3 SV=1
A5G6H1 1.61e-63 442 814 1 356
Tetraacyldisaccharide 4'-kinase OS=Geotalea uraniireducens (strain Rf4) OX=351605 GN=lpxK PE=3 SV=1
Q2IL55 1.92e-63 488 790 42 337
Tetraacyldisaccharide 4'-kinase OS=Anaeromyxobacter dehalogenans (strain 2CP-C) OX=290397 GN=lpxK PE=3 SV=1
B4UHQ4 6.85e-62 488 781 42 327
Tetraacyldisaccharide 4'-kinase OS=Anaeromyxobacter sp. (strain K) OX=447217 GN=lpxK PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.805763 0.189166 0.002459 0.000562 0.000444 0.001611

TMHMM  Annotations      download full data without filtering help

start end
3 25