You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000004437_00126
You are here: Home > Sequence: MGYG000004437_00126
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS1224 sp900549775 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UMGS1224; UMGS1224 sp900549775 | |||||||||||
| CAZyme ID | MGYG000004437_00126 | |||||||||||
| CAZy Family | GT35 | |||||||||||
| CAZyme Description | Glycogen phosphorylase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 106093; End: 108516 Strand: + | |||||||||||
Full Sequence Download help
| MTLKEKVDNV RNLIVKKLSH NFGISPENAT YEQFYKAVSL VLQDFMTDCQ SKFLSKMQDQ | 60 |
| RPKQVHYICM EFLLGKSLKN NLTNLKLEKV FSSALKSLGV NLEAVYAKEP DAALGNGGLG | 120 |
| RLAACFLDSL ATNAYPSIGY SLRYEHGVFL QKLIDGWQTE LPDFWLSGGS IWLAPKPEEA | 180 |
| VIVSFDGNVK ESWGEGFHNV KLEKTNDVIA VPYDMSITGY NCNGVSKLRL WAAESRGFNM | 240 |
| ELFNSGNYIR AVEQDAMASV ITKVLYPNDN HPEGKSLRLS QQYFLVSATI QDIVKKHLNI | 300 |
| YNTLDNLPEK ATIHLNDTHP VLAIPELMRL MLDECGYSWE RAFELVQKTF AFTNHTIMSE | 360 |
| ALEMWSEELI KRRLPRIYQI IVEINNRFVY ELKRQNCSDE TIYKTSIVKN GTIHMANLAV | 420 |
| VCSSCVNGVS ELHSNILKTK VFNDFYSITP EKFTNVTNGI AHRRWLCQAN PQLCSLISSL | 480 |
| IGNHFITSPL ELKNFEKFKD DASVLAKLKE IKLKNKTEMA KYVKDSTGIT VDPGSMFDVQ | 540 |
| IKRFHEYKRQ LMNALEILET YIDLKENKIS LAQFVPRTYI FAGKAASSYY FAKQIIKFIY | 600 |
| YLGETINNDK SIEDKMKVVF LENYSVSLAE KLIPASDISE QISLAGTEAS GTSNMKFMLN | 660 |
| GALTLGTLDG SNVEIFDSVG NENIFIFGMN AEEVFNLRKN SYNPMAYYNN SCAKKAIDQL | 720 |
| ALGVGAVRFE DISQYLITRD PYMVLADFSD YKNERQKAIS LYDSWEIWNK MSVVNIANAG | 780 |
| IFSADISIKN YAENIWHIKP LNEKSKS | 807 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT35 | 94 | 799 | 6.4e-257 | 0.9985163204747775 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK14986 | PRK14986 | 0.0 | 7 | 801 | 14 | 813 | glycogen phosphorylase; Provisional |
| COG0058 | GlgP | 0.0 | 2 | 800 | 1 | 750 | Glucan phosphorylase [Carbohydrate transport and metabolism]. |
| PRK14985 | PRK14985 | 0.0 | 22 | 799 | 21 | 797 | maltodextrin phosphorylase; Provisional |
| TIGR02093 | P_ylase | 0.0 | 14 | 798 | 1 | 794 | glycogen/starch/alpha-glucan phosphorylases. This family consists of phosphorylases. Members use phosphate to break alpha 1,4 linkages between pairs of glucose residues at the end of long glucose polymers, releasing alpha-D-glucose 1-phosphate. The nomenclature convention is to preface the name according to the natural substrate, as in glycogen phosphorylase, starch phosphorylase, maltodextrin phosphorylase, etc. Name differences among these substrates reflect differences in patterns of branching with alpha 1,6 linkages. Members include allosterically regulated and unregulated forms. A related family, TIGR02094, contains examples known to act well on particularly small alpha 1,4 glucans, as may be found after import from exogenous sources. [Energy metabolism, Biosynthesis and degradation of polysaccharides] |
| cd04300 | GT35_Glycogen_Phosphorylase | 0.0 | 11 | 798 | 1 | 795 | glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QNO18144.1 | 0.0 | 1 | 805 | 1 | 804 |
| QKO30335.1 | 0.0 | 1 | 801 | 1 | 800 |
| ARP49466.1 | 0.0 | 1 | 801 | 1 | 800 |
| QKN23059.1 | 0.0 | 1 | 801 | 1 | 800 |
| QEY35301.1 | 0.0 | 1 | 804 | 1 | 802 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3CEH_A | 1.09e-221 | 29 | 800 | 24 | 807 | Humanliver glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE5688 [Homo sapiens],3CEH_B Human liver glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE5688 [Homo sapiens],3CEJ_A Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE2865 [Homo sapiens],3CEJ_B Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE2865 [Homo sapiens],3CEM_A Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE9423 [Homo sapiens],3CEM_B Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE9423 [Homo sapiens] |
| 1XOI_A | 1.80e-221 | 29 | 804 | 46 | 833 | HumanLiver Glycogen Phosphorylase A complexed with Chloroindoloyl glycine amide [Homo sapiens],1XOI_B Human Liver Glycogen Phosphorylase A complexed with Chloroindoloyl glycine amide [Homo sapiens] |
| 1FC0_A | 2.54e-221 | 29 | 804 | 46 | 833 | HUMANLIVER GLYCOGEN PHOSPHORYLASE COMPLEXED WITH N-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE [Homo sapiens],1FC0_B HUMAN LIVER GLYCOGEN PHOSPHORYLASE COMPLEXED WITH N-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE [Homo sapiens],2ATI_A Glycogen Phosphorylase Inhibitors [Homo sapiens],2ATI_B Glycogen Phosphorylase Inhibitors [Homo sapiens] |
| 1FA9_A | 2.54e-221 | 29 | 804 | 46 | 833 | HUMANLIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH AMP [Homo sapiens] |
| 2QLL_A | 2.62e-221 | 29 | 804 | 47 | 834 | Humanliver glycogen phosphorylase- GL complex [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P0AC86 | 5.89e-231 | 7 | 801 | 14 | 813 | Glycogen phosphorylase OS=Escherichia coli (strain K12) OX=83333 GN=glgP PE=3 SV=1 |
| P0AC87 | 5.89e-231 | 7 | 801 | 14 | 813 | Glycogen phosphorylase OS=Shigella flexneri OX=623 GN=glgP PE=3 SV=1 |
| Q9CN90 | 6.70e-228 | 7 | 801 | 19 | 817 | Glycogen phosphorylase OS=Pasteurella multocida (strain Pm70) OX=272843 GN=glgP PE=3 SV=1 |
| P45180 | 5.37e-225 | 7 | 801 | 19 | 817 | Glycogen phosphorylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=glgP PE=3 SV=1 |
| O84250 | 3.43e-224 | 4 | 798 | 7 | 809 | Glycogen phosphorylase OS=Chlamydia trachomatis (strain D/UW-3/Cx) OX=272561 GN=glgP PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000035 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |