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CAZyme Information: MGYG000001450_00174

You are here: Home > Sequence: MGYG000001450_00174

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Nesterenkonia massiliensis
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Micrococcaceae; Nesterenkonia; Nesterenkonia massiliensis
CAZyme ID MGYG000001450_00174
CAZy Family GT2
CAZyme Description Glycosyltransferase Gtf1
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
792 MGYG000001450_1|CGC1 87300.79 5.317
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001450 2641047 Isolate not provided Europe
Gene Location Start: 177078;  End: 179456  Strand: +

Full Sequence      Download help

MITWWRTARA  LLSNDGATMQ  DSPQVSIVMP  VFNDEDWIAE  ALESCLSQTL  QEIEVICVDD60
ASTDDTPQII  ERYQEKDPRV  RLVRQPANLS  AFQARRVGIL  ESSAPYILFL  DGDDELDPRA120
AEKAVAKAES  THADLVGFGV  AVLGPNGNAV  LGYQRRLMPK  HSSLEGEEIL  KGLFPVGRPA180
QGQLWRFLFS  TDLLREAYSL  LPEDLVLSRV  NDLPITFLAL  ASAQRYVSMT  DLLYRYHFRR240
GGSGHQVAGL  EQFQFYCRGI  ESLESMVGAV  RTLARKTPDP  EPILDGYETA  RLSIIGNVLG300
YLLASASEEF  YQDYLEHLYS  LVSKADVVLA  AADYAPDAIP  VLAKHSTRAD  LTGREVRNVL360
LTTKVITTGG  VSLVLLAQAK  YLTQAGYQVT  IAAKSRGSVL  DGLPEGVKFV  EITGRRASTR420
LSQWAEICRT  ESIDVIIEHQ  VLYSKSWPSY  ALMAEAVGVP  TIGWIHSFAL  RPVYDLKDMI480
SFIRDQANCL  ASVVTLSPLD  VSFWKLQGVS  HTCYLPNPGS  PMLLESAGSA  AKKSAPEGAL540
KLIWWGRLEE  HTKQVSQLIE  IAAELRQLDV  NFRLTIIGPD  SPELTAADLK  ARAKSRNVED600
LVDLVGPLQG  EDLLNAIDAA  DMFVSTSILE  GYQLTLAEAQ  ARGLPAAMYE  LPWLTLVQEN660
RGIMPAAQGD  AAGLARKIKA  VAGDPDLYAQ  YSQASAEAAQ  RALSLDFSRL  YEQLVTGSLP720
EEYSPEPTLE  DAQQIIDWIV  FFTERHTGIR  GRRGRGPVAG  EKTLLRRALN  RVDRAAPALR780
PVKRRVKRLL  GR792

Enzyme Prediction      help

No EC number prediction in MGYG000001450_00174.

CAZyme Signature Domains help

Created with Snap397911815819823727731635639643547551455459463367371275226162GT2533690GT4
Family Start End Evalue family coverage
GT2 26 162 4.6e-33 0.8235294117647058
GT4 533 690 2.4e-17 0.9625

CDD Domains      download full data without filtering help

Created with Snap3979118158198237277316356396435475514554594633673712752369712GT4_PimA-like26118Glycos_transf_227118Glyco_tranf_GTA_type21119WcaA369718RfaB
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03801 GT4_PimA-like 1.00e-30 369 712 14 366
phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
pfam00535 Glycos_transf_2 8.50e-30 26 118 1 93
Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd00761 Glyco_tranf_GTA_type 8.53e-29 27 118 1 92
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
COG0463 WcaA 1.12e-28 21 119 1 99
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
COG0438 RfaB 3.94e-25 369 718 15 381
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Created with Snap397911815819823727731635639643547551455459463367371275219790SDT47398.1|GT2|GT419750QKJ20351.1|GT2|GT419790QDE35757.1|GT2|GT419791QKJ20348.1|GT2|GT419727QAY60617.1|GT2|GT4
Hit ID E-Value Query Start Query End Hit Start Hit End
SDT47398.1 0.0 19 790 1 798
QKJ20351.1 2.55e-293 19 750 1 732
QDE35757.1 3.19e-279 19 790 1 794
QKJ20348.1 7.36e-278 19 791 1 776
QAY60617.1 4.00e-272 19 727 1 714

PDB Hits      download full data without filtering help

Created with Snap3979118158198237277316356396435475514554594633673712752262565TZE_C262565TZ8_A191145HEA_A151222Z86_A151222Z87_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5TZE_C 2.04e-13 26 256 4 222
Crystalstructure of S. aureus TarS in complex with UDP-GlcNAc [Staphylococcus aureus],5TZE_E Crystal structure of S. aureus TarS in complex with UDP-GlcNAc [Staphylococcus aureus],5TZI_C Crystal structure of S. aureus TarS 1-349 [Staphylococcus aureus],5TZJ_A Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc [Staphylococcus aureus],5TZJ_C Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc [Staphylococcus aureus],5TZK_C Crystal structure of S. aureus TarS 1-349 in complex with UDP [Staphylococcus aureus]
5TZ8_A 4.65e-13 26 256 4 222
Crystalstructure of S. aureus TarS [Staphylococcus aureus],5TZ8_B Crystal structure of S. aureus TarS [Staphylococcus aureus],5TZ8_C Crystal structure of S. aureus TarS [Staphylococcus aureus]
5HEA_A 2.55e-12 19 114 1 95
CgTstructure in hexamer [Streptococcus parasanguinis FW213],5HEA_B CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEA_C CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEC_A CgT structure in dimer [Streptococcus parasanguinis FW213],5HEC_B CgT structure in dimer [Streptococcus parasanguinis FW213]
2Z86_A 6.11e-12 15 122 367 473
Crystalstructure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GlcUA and UDP [Escherichia coli],2Z86_B Crystal structure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GlcUA and UDP [Escherichia coli],2Z86_C Crystal structure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GlcUA and UDP [Escherichia coli],2Z86_D Crystal structure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GlcUA and UDP [Escherichia coli]
2Z87_A 6.11e-12 15 122 366 472
Crystalstructure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GalNAc and UDP [Escherichia coli],2Z87_B Crystal structure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GalNAc and UDP [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap397911815819823727731635639643547551455459463367371275223236sp|P71059|EPSJ_BACSU23150sp|Q57022|Y868_HAEIN22136sp|A0A0H2UR96|GLYG_STRPN24271sp|E0U4V7|TARQ_BACSH19142sp|P71054|EPSE_BACSU
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P71059 2.83e-19 23 236 3 211
Uncharacterized glycosyltransferase EpsJ OS=Bacillus subtilis (strain 168) OX=224308 GN=epsJ PE=2 SV=1
Q57022 2.74e-16 23 150 4 131
Uncharacterized glycosyltransferase HI_0868 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=HI_0868 PE=3 SV=1
A0A0H2UR96 5.43e-14 22 136 2 116
Glycosyltransferase GlyG OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=glyG PE=1 SV=1
E0U4V7 1.63e-12 24 271 2 234
Poly(ribitol-phosphate) beta-glucosyltransferase OS=Bacillus spizizenii (strain ATCC 23059 / NRRL B-14472 / W23) OX=655816 GN=tarQ PE=1 SV=1
P71054 1.89e-12 19 142 1 126
Putative glycosyltransferase EpsE OS=Bacillus subtilis (strain 168) OX=224308 GN=epsE PE=2 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000053 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001450_00174.